Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uterine Hemorrhage | D014592 | 6 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hand KV et al. | Examining acute and chronic effects of short- and long-chain fatty acids on peptide YY (PYY) gene expression, cellular storage and secretion in STC-1 cells. | 2013 | Eur J Nutr | pmid:22926626 |
| Jaschonek K et al. | Desensitization of platelets to iloprost. Loss of specific binding sites and heterologous desensitization of adenylate cyclase. | 1988 | Eur. J. Pharmacol. | pmid:2452749 |
| Youdim MB et al. | The glycine-prodrug, milacemide, increases the seizure threshold due to hyperbaric oxygen; prevention by 1-deprenyl. | 1988 | Eur. J. Pharmacol. | pmid:3138141 |
| Range SP et al. | Selectivity of cyclo-oxygenase inhibitors in human pulmonary epithelial and smooth muscle cells. | 2000 | Eur. Respir. J. | pmid:10780769 |
| van den Meerschaut L and Sünder A | The homeopathic preparation Nervoheel N can offer an alternative to lorazepam therapy for mild nervous disorders. | 2009 | Evid Based Complement Alternat Med | pmid:18955261 |
| Mueller A et al. | Body composition and bone mineral density in male-to-female transsexuals during cross-sex hormone therapy using gonadotrophin-releasing hormone agonist. | 2011 | Exp. Clin. Endocrinol. Diabetes | pmid:20625973 |
| Sigel H | The coordinating properties of d-biotin. | 1981 | Experientia | pmid:7286129 |
| Kuznetsov DD et al. | Intravesical valrubicin in the treatment of carcinoma in situ of the bladder. | 2001 | Expert Opin Pharmacother | pmid:11585003 |
| Kumar A et al. | Redox homeostasis in mycobacteria: the key to tuberculosis control? | 2011 | Expert Rev Mol Med | pmid:22172201 |
| Sorokin DY et al. | Propionate and butyrate dependent bacterial sulfate reduction at extremely haloalkaline conditions and description of Desulfobotulus alkaliphilus sp. nov. | 2010 | Extremophiles | pmid:19888546 |
| de Bernard M et al. | TPA and butyrate increase cell sensitivity to the vacuolating toxin of Helicobacter pylori. | 1998 | FEBS Lett. | pmid:9781682 |
| Guan LL et al. | Linkage of microbial ecology to phenotype: correlation of rumen microbial ecology to cattle's feed efficiency. | 2008 | FEMS Microbiol. Lett. | pmid:18785930 |
| Kendall MM et al. | Butyrate- and propionate-degrading syntrophs from permanently cold marine sediments in Skan Bay, Alaska, and description of Algorimarina butyrica gen. nov., sp. nov. | 2006 | FEMS Microbiol. Lett. | pmid:16907746 |
| Ghanem ME et al. | The effect of luteal phase support protocol on cycle outcome and luteal phase hormone profile in long agonist protocol intracytoplasmic sperm injection cycles: a randomized clinical trial. | 2009 | Fertil. Steril. | pmid:19464001 |
| Adaikan PG et al. | Efficacy of red clover isoflavones in the menopausal rabbit model. | 2009 | Fertil. Steril. | pmid:18973881 |
| Chen X and Chen SL | A woman with premature ovarian failure induced by Tripterygium wilfordii Hook.f. gives birth to a healthy child. | 2011 | Fertil. Steril. | pmid:21640345 |
| Seelig AS et al. | Comparison of cryopreservation outcome with gonadotropin-releasing hormone agonists or antagonists in the collecting cycle. | 2002 | Fertil. Steril. | pmid:11872197 |
| Serhal PF and Craft IL | Ovum donation--a simplified approach. | 1987 | Fertil. Steril. | pmid:2440730 |
| Seidman DS et al. | Estradiol valerate as a possible endocrine reproductive disruptor: evidence from an in vivo rat model. | 2009 | Fertil. Steril. | pmid:18973879 |
| Yang JH et al. | Hormone replacement therapy reverses the decrease in natural killer cytotoxicity but does not reverse the decreases in the T-cell subpopulation or interferon-gamma production in postmenopausal women. | 2000 | Fertil. Steril. | pmid:10927042 |