Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| CORSE J et al. | Alpha-Amino-beta-mercapto-n-valeric acid hydrochloride. | 1948 | J. Am. Chem. Soc. | pmid:18918849 |
| Khenkin AM and Neumann R | Oxidative C-C bond cleavage of primary alcohols and vicinal diols catalyzed by H5PV2Mo10O40 by an electron transfer and oxygen transfer reaction mechanism. | 2008 | J. Am. Chem. Soc. | pmid:18841966 |
| Rishel MJ et al. | Conformationally constrained analogues of bleomycin A5. | 2003 | J. Am. Chem. Soc. | pmid:12926941 |
| Dangel BD et al. | Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation. | 2001 | J. Am. Chem. Soc. | pmid:11506585 |
| Kristensen NB and Harmon DL | Effects of adding valerate, caproate, and heptanoate to ruminal buffers on splanchnic metabolism in steers under washed-rumen conditions. | 2005 | J. Anim. Sci. | pmid:16024710 |
| Arrizon A et al. | Feeding value of dried shredded sugarbeets as a partial replacement for steam-flaked corn in finishing diets for feedlot cattle. | 2012 | J. Anim. Sci. | pmid:22648752 |
| Kerr KR et al. | Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. | 2012 | J. Anim. Sci. | pmid:22003235 |
| Baisden LA et al. | n-Valeric acid in stomachs and on unwashed hair of swine. | 1972 | J. Anim. Sci. | pmid:5039919 |
| Barry KA et al. | Adaptation of healthy adult cats to select dietary fibers in vivo affects gas and short-chain fatty acid production from fiber fermentation in vitro. | 2011 | J. Anim. Sci. | pmid:21531846 |
| Barry KA et al. | Dietary cellulose, fructooligosaccharides, and pectin modify fecal protein catabolites and microbial populations in adult cats. | 2010 | J. Anim. Sci. | pmid:20495116 |
| Goiri I et al. | Use of chitosans to modulate ruminal fermentation of a 50:50 forage-to-concentrate diet in sheep. | 2010 | J. Anim. Sci. | pmid:19854994 |
| Varel VH et al. | Odorant production and persistence of Escherichia coli in manure slurries from cattle fed zero, twenty, forty, or sixty percent wet distillers grains with solubles. | 2008 | J. Anim. Sci. | pmid:18676716 |
| Robles V et al. | Effects of feeding frequency on intake, ruminal fermentation, and feeding behavior in heifers fed high-concentrate diets. | 2007 | J. Anim. Sci. | pmid:17609471 |
| Kim SC et al. | Effects of dietary n-6:n-3 fatty acid ratio on feed intake, digestibility, and fatty acid profiles of the ruminal contents, liver, and muscle of growing lambs. | 2007 | J. Anim. Sci. | pmid:17121972 |
| Cardozo PW et al. | Effects of natural plant extracts on ruminal protein degradation and fermentation profiles in continuous culture. | 2004 | J. Anim. Sci. | pmid:15542469 |
| Manzanilla EG et al. | Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. | 2004 | J. Anim. Sci. | pmid:15542467 |
| Kristensen NB and Harmon DL | Effect of increasing ruminal butyrate absorption on splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. | 2004 | J. Anim. Sci. | pmid:15537776 |
| Kristensen NB and Harmon DL | Splanchnic metabolism of volatile fatty acids absorbed from the washed reticulorumen of steers. | 2004 | J. Anim. Sci. | pmid:15309950 |
| Kristensen NB | Rumen microbial sequestration of [2-(13)C]acetate in cattle. | 2001 | J. Anim. Sci. | pmid:11583438 |
| Bandyk CA et al. | Effect of ruminal vs postruminal administration of degradable protein on utilization of low-quality forage by beef steers. | 2001 | J. Anim. Sci. | pmid:11204704 |