Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Choi GG et al. | Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69. | 2003 | Biotechnol. Lett. | pmid:12882163 |
| Wallace RJ et al. | Eubacterium pyruvativorans sp. nov., a novel non-saccharolytic anaerobe from the rumen that ferments pyruvate and amino acids, forms caproate and utilizes acetate and propionate. | 2003 | Int. J. Syst. Evol. Microbiol. | pmid:12892112 |
| Bernard JK et al. | Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea. | 2003 | J. Dairy Sci. | pmid:14672196 |
| Tsukahara T et al. | Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa. | 2003 | J. Nutr. Sci. Vitaminol. | pmid:14974732 |
| Voelker JA and Allen MS | Pelleted beet pulp substituted for high-moisture corn: 3. Effects on ruminal fermentation, pH, and microbial protein efficiency in lactating dairy cows. | 2003 | J. Dairy Sci. | pmid:14672186 |
| Simons CT et al. | Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation. | 2003 | Brain Res. | pmid:14575899 |
| Donzello MP et al. | Synthesis, X-ray crystal structure, UV/visible linear and nonlinear (optical limiting) spectral properties of symmetrical and unsymmetrical porphyrazines with annulated 1,2,5-thiadiazole and 1,4-diamyloxybenzene moieties. | 2003 | Chemistry | pmid:12953187 |
| Mancuso G et al. | Efficacy of betamethasone valerate foam formulation in comparison with betamethasone dipropionate lotion in the treatment of mild-to-moderate alopecia areata: a multicenter, prospective, randomized, controlled, investigator-blinded trial. | 2003 | Int. J. Dermatol. | pmid:12839615 |
| Simons CT et al. | Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis. | 2003 | Chem. Senses | pmid:12714448 |
| Schroeder JW | Optimizing the level of wet corn gluten feed in the diet of lactating dairy cows. | 2003 | J. Dairy Sci. | pmid:12703621 |
| Song R et al. | Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates. | 2003 | J. Inorg. Biochem. | pmid:12888269 |
| Lakshman K and Shamala TR | Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti. | 2003 | Biotechnol. Lett. | pmid:12882285 |
| Batstone DJ et al. | Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. | 2003 | Biotechnol. Bioeng. | pmid:12966576 |
| Rishel MJ et al. | Conformationally constrained analogues of bleomycin A5. | 2003 | J. Am. Chem. Soc. | pmid:12926941 |
| Nadeau JA et al. | Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. | 2003 | Am. J. Vet. Res. | pmid:12693529 |
| Jacob TJ et al. | Psychophysical evaluation of responses to pleasant and mal-odour stimulation in human subjects; adaptation, dose response and gender differences. | 2003 | Int J Psychophysiol | pmid:12694902 |
| Vuotto ML et al. | Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution. | 2003 | J. Pharm. Pharmacol. | pmid:12724048 |
| Embleton JK and Tighe BJ | Polymers for biodegradable medical devices XI. Microencapsulation studies: characterization of hydrocortisone-loaded poly-hydroxybutyrate-hydroxyvalerate microspheres. | 2002 Nov-Dec | J Microencapsul | pmid:12569022 |
| Sanjuán A et al. | Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits. | 2002 Jul-Aug | Menopause | pmid:12082364 |
| Cherry N et al. | Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial. | 2002 Dec 21-28 | Lancet | pmid:12504395 |