Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Laerke HN and Jensen BB | D-tagatose has low small intestinal digestibility but high large intestinal fermentability in pigs. | 1999 | J. Nutr. | pmid:10222392 |
| Täuber VU | [Percutaneous absorption of diflucortolone valerate in guinea pigs and man (author's transl)]. | 1976 | Arzneimittelforschung | pmid:1036943 |
| Täuber VU et al. | [Comparative studies in man on the percutaneous absorption of diflucortolone valerate, betamethasone-17-valerate, beclomethasone dipropionate and fluocinolone acetonide]. | 1976 | Arzneimittelforschung | pmid:1036945 |
| Redden PR et al. | Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. | 1999 | Int J Pharm | pmid:10370185 |
| Erskine PT et al. | The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid. | 1999 | Protein Sci. | pmid:10386874 |
| Mitomo H et al. | Biosynthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) produced by Burkholderia cepacia D1. | 1999 | Int. J. Biol. Macromol. | pmid:10408637 |
| Lotti M and Moretto A | Promotion of organophosphate induced delayed polyneuropathy by certain esterase inhibitors. | 1999 | Chem. Biol. Interact. | pmid:10421491 |
| Varela A et al. | Effects of pentanoate, 4-pentenoate, 3-hydroxybutyrate and insulin on the tissue-levels of long-chain acyl CoA and acylcarnitine in the oxygenated and hypoxic rat atria. | 1999 | Arch. Physiol. Biochem. | pmid:10455555 |
| Sakata T et al. | Probiotic preparations dose-dependently increase net production rates of organic acids and decrease that of ammonia by pig cecal bacteria in batch culture. | 1999 | Dig. Dis. Sci. | pmid:10489936 |
| Gysler A et al. | Skin penetration and metabolism of topical glucocorticoids in reconstructed epidermis and in excised human skin. | 1999 | Pharm. Res. | pmid:10496654 |
| Gadda G et al. | Identification of an essential tyrosine residue in nitroalkane oxidase by modification with tetranitromethane. | 2000 | Biochemistry | pmid:10653664 |
| Gadda G and Fitzpatrick PF | Mechanism of nitroalkane oxidase: 2. pH and kinetic isotope effects. | 2000 | Biochemistry | pmid:10684621 |
| Diwan AD et al. | Nitric oxide modulates fracture healing. | 2000 | J. Bone Miner. Res. | pmid:10703937 |
| Paassilta M et al. | Insulin-like growth factor binding protein-1 (IGFBP-1) and IGF-I during oral and transdermal estrogen replacement therapy: relation to lipoprotein(a) levels. | 2000 | Atherosclerosis | pmid:10704627 |
| Bui CT et al. | Comparative study of reductive amination reaction on 5-(4-formyl-3,5-dimethoxyphenoxy)valeric acid and its monomethoxy analog using the Multipin approach. | 1998 | Mol. Divers. | pmid:10729900 |
| Range SP et al. | Selectivity of cyclo-oxygenase inhibitors in human pulmonary epithelial and smooth muscle cells. | 2000 | Eur. Respir. J. | pmid:10780769 |
| Wächtershäuser A et al. | PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833422 |
| Palmeira CM et al. | Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833431 |
| Propper DJ et al. | Phase II study of the oxygen saturation curve left shifting agent BW12C in combination with the hypoxia activated drug mitomycin C in advanced colorectal cancer. | 2000 | Br. J. Cancer | pmid:10839290 |