Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yen PM and Tashjian AH | Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells. | 1981 | Endocrinology | pmid:7238401 |
| Sigel H | The coordinating properties of d-biotin. | 1981 | Experientia | pmid:7286129 |
| Shimo T et al. | [Irritation test of dexamethasone valerate (DV-17) and other steroid ointments in rabbits. Skin and eye primary irritation tests, and skin cumulative irritation test]. | 1982 | J Toxicol Sci | pmid:7154133 |
| Shimo T et al. | [Comparative toxicity test of dexamethasone valerate (DV-17) and other steroid ointments in rats]. | 1982 | J Toxicol Sci | pmid:7154134 |
| Brown NA et al. | Chain length dependency of fatty acid and carbamate binding to serum albumin. | 1982 | Biochem. Pharmacol. | pmid:7159478 |
| Chang SC and Lee VH | Influence of chain length on the in vitro hydrolysis of model ester prodrugs by ocular esterases. | 1982-1983 | Curr. Eye Res. | pmid:7186434 |
| Guggino SE et al. | Specificity and modes of the anion exchanger in dog renal microvillus membranes. | 1983 | Am. J. Physiol. | pmid:6859253 |
| Vilska S et al. | Long-term post-menopausal hormone therapy and serum HDL-C, total cholesterol and triglycerides. | 1983 | Maturitas | pmid:6415365 |
| Ishizawa H et al. | Effects of betamethasone 17 valerate on the cyclic AMP system of the pig skin epidermis. | 1983 | J. Dermatol. | pmid:6321577 |
| Borenstein DG et al. | Gas-liquid chromatographic analysis of synovial fluid: volatile short-chain fatty acids in septic arthritis. | 1983 | Ann. Rheum. Dis. | pmid:6882030 |
| Perlman BJ and Goldstein DB | Membrane-disordering potency and anticonvulsant action of valproic acid and other short-chain fatty acids. | 1984 | Mol. Pharmacol. | pmid:6431262 |
| Verschoyle RD et al. | The toxicity and neuropathology of 2,4,5-tribromoimidazole and its derivatives in rats. | 1984 | Arch. Toxicol. | pmid:6532374 |
| Stone TW | Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. | 1984 | Br. J. Pharmacol. | pmid:6546701 |
| Woodworth JR et al. | Quantitative analysis of phencyclidine and metabolites by capillary column gas chromatography. | 1984 Jan-Feb | J Anal Toxicol | pmid:6708471 |
| Ikeda Y et al. | Mechanism of action of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases. Direct evidence for carbanion formation as an intermediate step using enzyme-catalyzed C-2 proton/deuteron exchange in the absence of C-3 exchange. | 1985 | J. Biol. Chem. | pmid:3968064 |
| Peirce-Sandner SB et al. | Supplementation of dairy cow diets with ammonium salts of volatile fatty acids. | 1985 | J. Dairy Sci. | pmid:4078120 |
| De Lignieres B et al. | Biological effects of estradiol-17 beta in postmenopausal women: oral versus percutaneous administration. | 1986 | J. Clin. Endocrinol. Metab. | pmid:3080464 |
| Telford N et al. | The increase of anterior pituitary dopamine in aging C57BL/6J female mice is caused by ovarian steroids, not intrinsic pituitary aging. | 1986 | Neuroendocrinology | pmid:3724983 |
| Arvanov VL et al. | The effects of short-chain fatty acids on the neuronal membrane functions of Helix pomatia. II. Cholinoreceptive properties. | 1986 | Cell. Mol. Neurobiol. | pmid:3731214 |
| Saghyan AA et al. | The effects of short-chain fatty acids on the neuronal membrane functions of Helix pomatia. III. 22Na efflux from the cells. | 1986 | Cell. Mol. Neurobiol. | pmid:3829102 |