Valeric acid

Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.

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Introduction

To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Valeric acid?

Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Valeric acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Body Weight D001835 333 associated lipids
Glioma D005910 112 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Psoriasis D011565 47 associated lipids
Reye Syndrome D012202 14 associated lipids
Uterine Hemorrhage D014592 6 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Valeric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Valeric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Valeric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Valeric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Valeric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Valeric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Valeric acid

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Authors Title Published Journal PubMed Link
Iadevaia S and Mantzaris NV Genetic network driven control of PHBV copolymer composition. 2006 J. Biotechnol. pmid:16219380
Diwan AD et al. Nitric oxide modulates fracture healing. 2000 J. Bone Miner. Res. pmid:10703937
Snyder SE et al. Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity. 2001 J. Cereb. Blood Flow Metab. pmid:11176278
Njagi PG and Torto B Evidence for a compound in Comstock-Kellog glands modulating premating behavior in male desert locust, Schistocerca gregaria. 2002 J. Chem. Ecol. pmid:12049227
Mukabana WR et al. A novel synthetic odorant blend for trapping of malaria and other African mosquito species. 2012 J. Chem. Ecol. pmid:22426893
Smallegange RC et al. The effect of aliphatic carboxylic acids on olfaction-based host-seeking of the malaria mosquito Anopheles gambiae sensu stricto. 2009 J. Chem. Ecol. pmid:19626371
Zhao G et al. Determination of short-chain fatty acids in serum by hollow fiber supported liquid membrane extraction coupled with gas chromatography. 2007 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:17070116
De Lignieres B et al. Biological effects of estradiol-17 beta in postmenopausal women: oral versus percutaneous administration. 1986 J. Clin. Endocrinol. Metab. pmid:3080464
Idkowiak J et al. Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. 2011 J. Clin. Endocrinol. Metab. pmid:21190981
Valerio F et al. Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients: a pilot study. 2010 J. Clin. Gastroenterol. pmid:20495470
Johnson BA and Leon M Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration. 2000 J. Comp. Neurol. pmid:10861522
German DP Do herbivorous minnows have "plug-flow reactor" guts? Evidence from digestive enzyme activities, gastrointestinal fermentation, and luminal nutrient concentrations. 2009 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:19363616
Chung YH et al. Ruminal and blood responses to propylene glycol during frequent feeding. 2009 J. Dairy Sci. pmid:19700718
Karnati SK et al. Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. I. Fermentation, biohydrogenation, and microbial protein synthesis. 2009 J. Dairy Sci. pmid:19620669
Bernard JK et al. Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea. 2003 J. Dairy Sci. pmid:14672196
Penner GB et al. Effect of dietary forage to concentrate ratio on volatile fatty acid absorption and the expression of genes related to volatile fatty acid absorption and metabolism in ruminal tissue. 2009 J. Dairy Sci. pmid:19448011
Rico DE et al. Effects of partially replacing dietary starch with dry glycerol in a lactating cow diet on ruminal fermentation during continuous culture. 2012 J. Dairy Sci. pmid:22612964
Taylor CC and Allen MS Corn grain endosperm type and brown midrib 3 corn silage: ruminal fermentation and N partitioning in lactating cows. 2005 J. Dairy Sci. pmid:15778312
Voelker JA and Allen MS Pelleted beet pulp substituted for high-moisture corn: 3. Effects on ruminal fermentation, pH, and microbial protein efficiency in lactating dairy cows. 2003 J. Dairy Sci. pmid:14672186
Schroeder JW Optimizing the level of wet corn gluten feed in the diet of lactating dairy cows. 2003 J. Dairy Sci. pmid:12703621
Khalili H and Huhtanen P Effect of casein infusion in the rumen, duodenum or both sites on factors affecting forage intake and performance of dairy cows fed red clover-grass silage. 2002 J. Dairy Sci. pmid:12018436
Ahvenjärvi S et al. Effects of replacing grass silage with barley silage in dairy cow diets. 2006 J. Dairy Sci. pmid:16606738
Klusmeyer TH et al. Effects of feeding or infusing ammonium salts of volatile fatty acids on ruminal fermentation, plasma characteristics, and milk production of cows. 1987 J. Dairy Sci. pmid:3571626
Kone P et al. Effect of the combination of monensin and isoacids on rumen fermentation in vitro. 1989 J. Dairy Sci. pmid:2600235
Peirce-Sandner SB et al. Supplementation of dairy cow diets with ammonium salts of volatile fatty acids. 1985 J. Dairy Sci. pmid:4078120
Resende Júnior JC et al. Comparison of techniques to determine the clearance of ruminal volatile fatty acids. 2006 J. Dairy Sci. pmid:16840627
Martínez ME et al. Effects of dilution rate and retention time of concentrate on efficiency of microbial growth, methane production, and ruminal fermentation in Rusitec fermenters. 2009 J. Dairy Sci. pmid:19620676
Soder KJ et al. Effect of incremental flaxseed supplementation of an herbage diet on methane output and ruminal fermentation in continuous culture. 2012 J. Dairy Sci. pmid:22720950
Martínez ME et al. Comparison of fermentation of diets of variable composition and microbial populations in the rumen of sheep and Rusitec fermenters. I. Digestibility, fermentation parameters, and microbial growth. 2010 J. Dairy Sci. pmid:20655438
Lingaas F and Tveit B Etiology of acetonemia in Norwegian cattle. 2. Effect of butyric acid, valeric acid, and putrescine. 1992 J. Dairy Sci. pmid:1452847
Brito AF et al. Alfalfa cut at sundown and harvested as baleage improves milk yield of late-lactation dairy cows. 2008 J. Dairy Sci. pmid:18832221
Bramley E et al. The definition of acidosis in dairy herds predominantly fed on pasture and concentrates. 2008 J. Dairy Sci. pmid:18096953
Felix A et al. Effect of feeding isoacids with urea on growth and nutrient utilization by lactating cows. 1980 J. Dairy Sci. pmid:7192295
Hall MB et al. Carbohydrate source and protein degradability alter lactation, ruminal, and blood measures. 2010 J. Dairy Sci. pmid:20059929
Miller-Webster T et al. Influence of yeast culture on ruminal microbial metabolism in continuous culture. 2002 J. Dairy Sci. pmid:12214993
Kristensen NB et al. Metabolism of silage alcohols in lactating dairy cows. 2007 J. Dairy Sci. pmid:17297111
Sutton JD et al. Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows. 2003 J. Dairy Sci. pmid:12647961
Cannon SJ et al. Inclusion of psyllium in milk replacer for neonatal calves. 2. Effects on volatile fatty acid concentrations, microbial populations, and gastrointestinal tract size. 2010 J. Dairy Sci. pmid:20855009
Boudon A et al. Effects of rumen or duodenal glucose infusions on intake in dairy cows fed fresh perennial ryegrass indoors. 2007 J. Dairy Sci. pmid:17699060
Besong S et al. Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. 2001 J. Dairy Sci. pmid:11467818
Golder HM et al. Effects of grain, fructose, and histidine on ruminal pH and fermentation products during an induced subacute acidosis protocol. 2012 J. Dairy Sci. pmid:22459843
Ishizawa H et al. Effects of betamethasone 17 valerate on the cyclic AMP system of the pig skin epidermis. 1983 J. Dermatol. pmid:6321577
Bassett JM et al. Regulation of insulin secretion in the ovine foetus in utero. Effects of sodium valerate on secretion and of adrenocorticotrophin-induced premature parturition on the insulin secretory response to glucose. 1973 J. Endocrinol. pmid:4345761
Dafopoulos K et al. The effect of estrogens on plasma ghrelin concentrations in women. 2010 J. Endocrinol. Invest. pmid:20348837
Punnonen R et al. Demonstration of estrogen receptors in the skin. 1980 Jul-Sep J. Endocrinol. Invest. pmid:7430556
Gadda G et al. Evidence for an essential arginine in the flavoprotein nitroalkane oxidase. 2001 J. Enzym. Inhib. pmid:11342284
Zanor MI et al. Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. 2009 J. Exp. Bot. pmid:19346240
Sakurazawa T and Ohkusa T Cytotoxicity of organic acids produced by anaerobic intestinal bacteria on cultured epithelial cells. 2005 J. Gastroenterol. pmid:16007394
Sentürk E et al. Treatment efficiency and VFA composition of a thermophilic anaerobic contact reactor treating food industry wastewater. 2010 J. Hazard. Mater. pmid:20022175
Saha SP et al. Incorporation of polyethylene glycol in polyhydroxyalkanoic acids accumulated by Azotobacter chroococcum MAL-201. 2006 J. Ind. Microbiol. Biotechnol. pmid:16550437
Khanna S and Srivastava AK Production of poly(3-hydroxybutyric-co-3-hydroxyvaleric acid) having a high hydroxyvalerate content with valeric acid feeding. 2007 J. Ind. Microbiol. Biotechnol. pmid:17268758
Song R et al. Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates. 2003 J. Inorg. Biochem. pmid:12888269
Hölzle E and Plewig G Effects of dermatitis, stripping, and steroids on the morphology of corneocytes. A new bioassay. 1977 J. Invest. Dermatol. pmid:864272
Pinto O et al. Synthesis of tetrahydronaphthalene lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition of human tumor cell lines. 2011 J. Med. Chem. pmid:21504224
Tomiyama T et al. Synthesis and biological activity of novel carbacyclins having bicyclic substituents on the omega-chain. 1989 J. Med. Chem. pmid:2666669
Jiracek J et al. S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase. 2006 J. Med. Chem. pmid:16789755
Bourel-Bonnet L et al. Solid-phase total synthesis of kahalalide A and related analogues. 2005 J. Med. Chem. pmid:15743176
Potu RB et al. The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. 2011 J. Microbiol. pmid:21538241
Brady GP and Sharp KA Decomposition of interaction free energies in proteins and other complex systems. 1995 J. Mol. Biol. pmid:7473761
Merrouche R et al. Dithiolopyrrolone antibiotic formation induced by adding valeric acid to the culture broth of Saccharothrix algeriensis. 2010 J. Nat. Prod. pmid:20507156
Crublet ML et al. Acylated triterpenoid saponins from the stem bark of Foetidia africana. 2002 J. Nat. Prod. pmid:12444677
Castillo P et al. Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera. 2002 J. Nat. Prod. pmid:11975504
Mahran A et al. Mortality of Pratylenchus penetrans by Volatile Fatty Acids from Liquid Hog Manure. 2008 J. Nematol. pmid:19259528
Manni L et al. Effect of exercise on ovarian morphology and expression of nerve growth factor and alpha(1)- and beta(2)-adrenergic receptors in rats with steroid-induced polycystic ovaries. 2005 J. Neuroendocrinol. pmid:16280032
Lapid H et al. Odorant concentration dependence in electroolfactograms recorded from the human olfactory epithelium. 2009 J. Neurophysiol. pmid:19657081
Dessirier JM et al. Sensitization, desensitization and stimulus-induced recovery of trigeminal neuronal responses to oral capsaicin and nicotine. 2000 J. Neurophysiol. pmid:11024077
Brasili E et al. Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. 2013 J. Nutr. pmid:23946343
Laerke HN and Jensen BB D-tagatose has low small intestinal digestibility but high large intestinal fermentability in pigs. 1999 J. Nutr. pmid:10222392
Tsukahara T et al. Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa. 2003 J. Nutr. Sci. Vitaminol. pmid:14974732
Kobayashi D and Sakata T Influence of temperature on short-chain fatty acid production by pig cecal bacteria in vitro. 2006 J. Nutr. Sci. Vitaminol. pmid:16637232
Seki M et al. A novel synthesis of (+)-biotin from L-cysteine. 2002 J. Org. Chem. pmid:12153250
Schaefer FW et al. Aerobic and anaerobic fermentation of glucose by Echinostoma liei. 1977 J. Parasitol. pmid:886405
Baisden LA et al. Comparison of pepsin and alkali digestion methods for determining n-valeric acid in trichinous swine muscle. 1972 J. Parasitol. pmid:4562322
Vuotto ML et al. Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution. 2003 J. Pharm. Pharmacol. pmid:12724048
Taniguchi K et al. Efficacy of a liposome preparation of anti-inflammatory steroid as an ocular drug-delivery system. 1988 J. Pharmacobio-dyn. pmid:3385602
Taniguchi K et al. Effects of Tween 80 and liposomes on the corneal permeability of anti-inflammatory steroids. 1988 J. Pharmacobio-dyn. pmid:3221301
Tune BM and Hsu CY Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates. 1995 J. Pharmacol. Exp. Ther. pmid:7616399
Nakazawa A et al. Evaluation of Adsorption Characteristics of a Fibrous Adsorbent Containing Zwitter-Ionic Functional Group, Targeting Organic Acids. 2017 J. UOEH pmid:28331124
Sato H and Shiogama Y Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. 2010 J. Vet. Med. Sci. pmid:19959888
Sato H Increased fecal lactate and decreased volatile fatty acid (VFA), particularly n-butyrate concentrations in diarrheic young calves. 2009 J. Vet. Med. Sci. pmid:19194088
Kien CL and Blauwiekel R Cecal infusion of butyrate does not alter cecal concentration of butyrate in piglets fed inulin. 2008 Jul-Aug JPEN J Parenter Enteral Nutr pmid:18596316
Cherry N et al. Oestrogen therapy for prevention of reinfarction in postmenopausal women: a randomised placebo controlled trial. 2002 Dec 21-28 Lancet pmid:12504395
Zhang J et al. Zeolite-fiber integrated optical chemical sensors for detection of dissolved organics in water. 2005 Langmuir pmid:16142937
Singh AK and Mallick N Enhanced production of SCL-LCL-PHA co-polymer by sludge-isolated Pseudomonas aeruginosa MTCC 7925. 2008 Lett. Appl. Microbiol. pmid:18221276
Yoshida S et al. Metabolism of fatty acids and lipid hydroperoxides in human body monitoring with Fourier transform Infrared Spectroscopy. 2009 Lipids Health Dis pmid:19627618
Koller M et al. Potential of various archae- and eubacterial strains as industrial polyhydroxyalkanoate producers from whey. 2007 Macromol Biosci pmid:17295410
Pederson EN and Srienc F Mass spectrometry feedback control for synthesis of polyhydroxyalkanoate granule microstructures in Ralstonia eutropha. 2004 Macromol Biosci pmid:15468214
Serafim LS et al. The influence of process parameters on the characteristics of polyhydroxyalkanoates produced by mixed cultures. 2008 Macromol Biosci pmid:18157852
Basant A et al. Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression. 2010 Malar. J. pmid:20412601
Olanga EA et al. Attraction of Anopheles gambiae to odour baits augmented with heat and moisture. 2010 Malar. J. pmid:20051143
Potts BC and Lam KS Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides. 2010 Mar Drugs pmid:20479958
L'Hermite M et al. From oral contraception to hormone replacement therapy: towards a continuum? 1988 Maturitas pmid:3237108
Vitale C et al. Effect of estradiol valerate alone or in association with cyproterone acetate upon vascular function of postmenopausal women at increased risk for cardiovascular disease. 2001 Maturitas pmid:11731185
Vilska S et al. Long-term post-menopausal hormone therapy and serum HDL-C, total cholesterol and triglycerides. 1983 Maturitas pmid:6415365
Saletu B et al. Hormone replacement therapy and vigilance: double-blind, placebo-controlled EEG-mapping studies with an estrogen-progestogen combination (Climodien, Lafamme) versus estrogen alone in menopausal syndrome patients. 2002 Maturitas pmid:12443834
Osterloh J et al. Biochemical relationships between Reye's and Reye's-like metabolic and toxicological syndromes. 1989 Jul-Aug Med Toxicol Adverse Drug Exp pmid:2671597
Chen FP et al. Comparison of transdermal and oral estrogen-progestin replacement therapy: effects on cardiovascular risk factors. 2001 Sep-Oct Menopause pmid:11528361
Sanjuán A et al. Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits. 2002 Jul-Aug Menopause pmid:12082364
Taurino C et al. Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin. 2011 Microb. Cell Fact. pmid:22008254
Galindo E et al. Molecular and bioengineering strategies to improve alginate and polydydroxyalkanoate production by Azotobacter vinelandii. 2007 Microb. Cell Fact. pmid:17306024