Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tomoda K et al. | Cigarette smoke decreases organic acids levels and population of bifidobacterium in the caecum of rats. | 2011 | J Toxicol Sci | pmid:21628954 |
| Jawara M et al. | Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia. | 2011 | PLoS ONE | pmid:21637337 |
| Chen X and Chen SL | A woman with premature ovarian failure induced by Tripterygium wilfordii Hook.f. gives birth to a healthy child. | 2011 | Fertil. Steril. | pmid:21640345 |
| Nascimento FJ et al. | Topical betamethasone and hyaluronidase in the treatment of phimosis in boys: a double-blind, randomized, placebo-controlled trial. | 2011 May-Jun | Int Braz J Urol | pmid:21756378 |
| Glogauer A et al. | Identification and characterization of a new true lipase isolated through metagenomic approach. | 2011 | Microb. Cell Fact. | pmid:21762508 |
| Kuldeep C et al. | Randomized comparison of topical betamethasone valerate foam, intralesional triamcinolone acetonide and tacrolimus ointment in management of localized alopecia areata. | 2011 | Int J Trichology | pmid:21769231 |
| Lombard J and Moreira D | Early evolution of the biotin-dependent carboxylase family. | 2011 | BMC Evol. Biol. | pmid:21827699 |
| Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
| Vujić JM et al. | Stereospecific ligands and their complexes. Part VII. Synthesis, characterization and in vitro antitumoral activity of platinum(II) complexes with O,O'-dialkyl esters of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)pentanoic acid. | 2011 | Eur J Med Chem | pmid:21840630 |
| Prakash S et al. | Gut microbiota: next frontier in understanding human health and development of biotherapeutics. | 2011 | Biologics | pmid:21847343 |
| Hoare DJ et al. | Modeling peripheral olfactory coding in Drosophila larvae. | 2011 | PLoS ONE | pmid:21857978 |
| Micks E and Jensen JT | Estradiol valerate and dienogest: a novel four-phasic oral contraceptive pill effective for pregnancy prevention and treatment of heavy menstrual bleeding. | 2011 | Womens Health (Lond Engl) | pmid:21879819 |
| Suzzi G | From wild strain to domesticated strain: the philosophy of microbial diversity in foods. | 2011 | Front Microbiol | pmid:21887153 |
| Kiley JW and Shulman LP | Estradiol valerate and dienogest: a new approach to oral contraception. | 2011 | Int J Womens Health | pmid:21892339 |
| Graue J et al. | Degradation of cyanobacterial biomass in anoxic tidal-flat sediments: a microcosm study of metabolic processes and community changes. | 2012 | ISME J | pmid:21918576 |
| Pellegrino M et al. | A natural polymorphism alters odour and DEET sensitivity in an insect odorant receptor. | 2011 | Nature | pmid:21937991 |
| Gross NB et al. | Cortical ionotropic glutamate receptor antagonism protects against methamphetamine-induced striatal neurotoxicity. | 2011 | Neuroscience | pmid:21946008 |
| Moita R and Lemos PC | Biopolymers production from mixed cultures and pyrolysis by-products. | 2012 | J. Biotechnol. | pmid:21983233 |
| Rubino T and Parolaro D | Sexually dimorphic effects of cannabinoid compounds on emotion and cognition. | 2011 | Front Behav Neurosci | pmid:21991251 |
| Kerr KR et al. | Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. | 2012 | J. Anim. Sci. | pmid:22003235 |
| Poli A et al. | Synthesis, production, and biotechnological applications of exopolysaccharides and polyhydroxyalkanoates by archaea. | 2011 | Archaea | pmid:22007151 |
| Taurino C et al. | Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin. | 2011 | Microb. Cell Fact. | pmid:22008254 |
| Tyndall V et al. | Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats. | 2012 | Reproduction | pmid:22016380 |
| Chee JY et al. | Expression of Aeromonas caviae polyhydroxyalkanoate synthase gene in Burkholderia sp. USM (JCM15050) enables the biosynthesis of SCL-MCL PHA from palm oil products. | 2012 | J. Appl. Microbiol. | pmid:22054430 |
| Kilner J et al. | A proteomic analysis of differential cellular responses to the short-chain fatty acids butyrate, valerate and propionate in colon epithelial cancer cells. | 2012 | Mol Biosyst | pmid:22075547 |
| Grégoire P et al. | Desulfosoma profundi sp. nov., a thermophilic sulfate-reducing bacterium isolated from a deep terrestrial geothermal spring in France. | 2012 | Antonie Van Leeuwenhoek | pmid:22120904 |
| Qiao X et al. | A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers. | 2012 | Steroids | pmid:22133544 |
| Jensen JM et al. | Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis. | 2012 | Allergy | pmid:22142306 |
| Kumar A et al. | Redox homeostasis in mycobacteria: the key to tuberculosis control? | 2011 | Expert Rev Mol Med | pmid:22172201 |
| Weickert MO et al. | Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity. | 2011 | Nutr Metab (Lond) | pmid:22177085 |
| Sarlea M et al. | Homogeneous catalysis of valeronitrile hydrolysis under supercritical conditions. | 2012 | ChemSusChem | pmid:22190404 |
| Gambadauro P et al. | Intrauterine Adhesions following Conservative Treatment of Uterine Fibroids. | 2012 | Obstet Gynecol Int | pmid:22190959 |
| Goh J et al. | The PEX7-mediated peroxisomal import system is required for fungal development and pathogenicity in Magnaporthe oryzae. | 2011 | PLoS ONE | pmid:22194815 |
| Dalmasso M et al. | A temporal-omic study of Propionibacterium freudenreichii CIRM-BIA1 adaptation strategies in conditions mimicking cheese ripening in the cold. | 2012 | PLoS ONE | pmid:22253706 |
| Zhang J et al. | Synthesis and insecticidal activities of new ester-derivatives of Celangulin-V. | 2011 | Int J Mol Sci | pmid:22272151 |
| Chang HF et al. | Synthesis of poly(3-hydroxybutyrate/3-hydroxyvalerate) from propionate-fed activated sludge under various carbon sources. | 2012 | Bioresour. Technol. | pmid:22277212 |
| Banel A et al. | Determination of SCFAs in water using GC-FID. Selection of the separation system. | 2012 | Anal. Chim. Acta | pmid:22284873 |
| Cleland TA et al. | Sequential mechanisms underlying concentration invariance in biological olfaction. | 2011 | Front Neuroeng | pmid:22287949 |
| Reimer RA et al. | Faecal short chain fatty acids in healthy subjects participating in a randomised controlled trial examining a soluble highly viscous polysaccharide versus control. | 2012 | J Hum Nutr Diet | pmid:22320902 |
| Nery J et al. | Influence of dietary protein content and source on colonic fermentative activity in dogs differing in body size and digestive tolerance. | 2012 | J. Anim. Sci. | pmid:22328724 |
| Kamath MS et al. | Blastocyst cryopreservation using solid surface vitrification: A preliminary study. | 2011 | J Hum Reprod Sci | pmid:22346077 |
| Brezina PR et al. | The impact of luteal phase support on endometrial estrogen and progesterone receptor expression: a randomized control trial. | 2012 | Reprod. Biol. Endocrinol. | pmid:22360924 |
| Timmers RA et al. | Microbial community structure elucidates performance of Glyceria maxima plant microbial fuel cell. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22361855 |
| Fichtel K et al. | Isolation of sulfate-reducing bacteria from sediments above the deep-subseafloor aquifer. | 2012 | Front Microbiol | pmid:22363336 |
| Donoghue JF et al. | Dilated thin-walled blood and lymphatic vessels in human endometrium: a potential role for VEGF-D in progestin-induced break-through bleeding. | 2012 | PLoS ONE | pmid:22383980 |
| Choi KH et al. | Efficiency of laser-assisted intracytoplasmic sperm injection in a human assisted reproductive techniques program. | 2011 | Clin Exp Reprod Med | pmid:22384434 |
| Brault G et al. | Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2). | 2012 | PLoS ONE | pmid:22396747 |
| Berni Canani R et al. | The epigenetic effects of butyrate: potential therapeutic implications for clinical practice. | 2012 | Clin Epigenetics | pmid:22414433 |
| Mukabana WR et al. | A novel synthetic odorant blend for trapping of malaria and other African mosquito species. | 2012 | J. Chem. Ecol. | pmid:22426893 |
| Xiccato G et al. | Effect of decreasing dietary protein level and replacing starch with soluble fibre on digestive physiology and performance of growing rabbits. | 2011 | Animal | pmid:22440170 |
| Røjen BA et al. | Urea and short-chain fatty acids metabolism in Holstein cows fed a low-nitrogen grass-based diet. | 2008 | Animal | pmid:22443564 |
| González LA et al. | Increasing sodium bicarbonate level in high-concentrate diets for heifers. I. Effects on intake, water consumption and ruminal fermentation. | 2008 | Animal | pmid:22443595 |
| Carro MD et al. | Comparison of microbial fermentation of high- and low-forage diets in Rusitec, single-flow continuous-culture fermenters and sheep rumen. | 2009 | Animal | pmid:22444376 |
| Sankar R et al. | Detection of oestrous-related odour in bovine ( Bos taurus) saliva: bioassay of identified compounds. | 2007 | Animal | pmid:22444887 |
| Golder HM et al. | Effects of grain, fructose, and histidine on ruminal pH and fermentation products during an induced subacute acidosis protocol. | 2012 | J. Dairy Sci. | pmid:22459843 |
| Kim YH and Kim KH | Novel approach to test the relative recovery of liquid-phase standard in sorbent-tube analysis of gaseous volatile organic compounds. | 2012 | Anal. Chem. | pmid:22468653 |
| Can Güven S and Laska M | Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. | 2012 | PLoS ONE | pmid:22479594 |
| Laskov I et al. | Successful pregnancy following transfer of frozen-thawed embryos in a patient with pseudomyxoma peritonei who underwent peritonectomy and bilateral oophorectomy. | 2012 | J Gynecol Oncol | pmid:22523631 |
| Vhile SG et al. | Feeding Jerusalem artichoke reduced skatole level and changed intestinal microbiota in the gut of entire male pigs. | 2012 | Animal | pmid:22558928 |
| de Oliveira CP et al. | Multiple headspace-solid-phase microextraction as a powerful tool for the quantitative determination of volatile radiolysis products in a multilayer food packaging material sterilized with γ-radiation. | 2012 | J Chromatogr A | pmid:22609166 |
| Rico DE et al. | Effects of partially replacing dietary starch with dry glycerol in a lactating cow diet on ruminal fermentation during continuous culture. | 2012 | J. Dairy Sci. | pmid:22612964 |
| Lucena E et al. | INVO procedure: minimally invasive IVF as an alternative treatment option for infertile couples. | 2012 | ScientificWorldJournal | pmid:22645435 |
| Arrizon A et al. | Feeding value of dried shredded sugarbeets as a partial replacement for steam-flaked corn in finishing diets for feedlot cattle. | 2012 | J. Anim. Sci. | pmid:22648752 |
| Mendes JB et al. | PHBV/PCL microparticles for controlled release of resveratrol: physicochemical characterization, antioxidant potential, and effect on hemolysis of human erythrocytes. | 2012 | ScientificWorldJournal | pmid:22666135 |
| Karlsson A et al. | Impact of trace element addition on degradation efficiency of volatile fatty acids, oleic acid and phenyl acetate and on microbial populations in a biogas digester. | 2012 | J. Biosci. Bioeng. | pmid:22683024 |
| Das S et al. | Facile total synthesis of (-)-(5R,6S)-6-acetoxy-5-hexadecanolide from carbohydrate, a mosquito oviposition attractant pheromone. | 2012 | Carbohydr. Res. | pmid:22687338 |
| Soder KJ et al. | Effect of incremental flaxseed supplementation of an herbage diet on methane output and ruminal fermentation in continuous culture. | 2012 | J. Dairy Sci. | pmid:22720950 |
| Hollister EB et al. | Mesophilic and thermophilic conditions select for unique but highly parallel microbial communities to perform carboxylate platform biomass conversion. | 2012 | PLoS ONE | pmid:22761870 |
| Gainsford GJ et al. | tert-Butyl (2R,4aR,5aR,11aS,12R,12aR)-8-[bis-(tert-but-oxycarbon-yl)amino]-12-hydroxy-2-meth-oxy-2,10-dioxo-4,4a,5a,6,9,10,11,11a,12,12a-deca-hydro-2H-1,3,5-trioxa-6,7,9,11-tetra-aza-2λ(5)-phosphatetra-cene-6-carboxyl-ate methanol monosolvate monohydrate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22798903 |
| Cruz G et al. | Temporal window in which exposure to estradiol permanently modifies ovarian function causing polycystic ovary morphology in rats. | 2012 | Fertil. Steril. | pmid:22854013 |
| Hand KV et al. | Examining acute and chronic effects of short- and long-chain fatty acids on peptide YY (PYY) gene expression, cellular storage and secretion in STC-1 cells. | 2013 | Eur J Nutr | pmid:22926626 |
| Tjellström B et al. | Effect of exclusive enteral nutrition on gut microflora function in children with Crohn's disease. | 2012 | Scand. J. Gastroenterol. | pmid:23016828 |
| Fischer D et al. | The repelling effect of plant secondary metabolites on water voles, Arvicola amphibius. | 2013 | Pest Manag. Sci. | pmid:23225271 |
| Špoljarić IV et al. | Mathematical modeling of poly[(R)-3-hydroxyalkanoate] synthesis by Cupriavidus necator DSM 545 on substrates stemming from biodiesel production. | 2013 | Bioresour. Technol. | pmid:23454805 |
| Xin L et al. | Electricity storage in biofuels: selective electrocatalytic reduction of levulinic acid to valeric acid or γ-valerolactone. | 2013 | ChemSusChem | pmid:23457116 |
| Jakobsdottir G et al. | Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. | 2013 | Scand. J. Gastroenterol. | pmid:23600961 |
| Takagaki A and Nanjo F | Catabolism of (+)-catechin and (-)-epicatechin by rat intestinal microbiota. | 2013 | J. Agric. Food Chem. | pmid:23621128 |
| Emerson B et al. | Gas chromatography-mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards. | 2013 | Forensic Sci. Int. | pmid:23683902 |
| Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
| Jang M et al. | Monitoring of urinary metabolites of JWH-018 and JWH-073 in legal cases. | 2013 | Forensic Sci. Int. | pmid:23890611 |
| Brasili E et al. | Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. | 2013 | J. Nutr. | pmid:23946343 |
| Jiang W et al. | Differential regulation of human cathelicidin LL-37 by free fatty acids and their analogs. | 2013 | Peptides | pmid:24140860 |
| Rico CM et al. | Effect of cerium oxide nanoparticles on the quality of rice ( Oryza sativa L.) grains. | 2013 | J. Agric. Food Chem. | pmid:24188281 |
| Suleymanian MA et al. | The effects of short-chain fatty acids on the neuronal membrane functions of Helix pomatia. I. Electrical properties. | 1986 | Cell. Mol. Neurobiol. | pmid:2425969 |
| Serhal PF and Craft IL | Ovum donation--a simplified approach. | 1987 | Fertil. Steril. | pmid:2440730 |
| Varga K et al. | Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells. | 2014 | Cell Calcium | pmid:24439526 |
| Jaschonek K et al. | Desensitization of platelets to iloprost. Loss of specific binding sites and heterologous desensitization of adenylate cyclase. | 1988 | Eur. J. Pharmacol. | pmid:2452749 |
| Varela A et al. | The effects of 4-pentenoic and pentanoic acids on the isolated rat atria. | 1988 | Arch. Int. Physiol. Biochim. | pmid:2474276 |
| Han JH et al. | The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41. | 2014 | PLoS ONE | pmid:24748202 |
| Varela A et al. | The effects of 4-pentenoic and pentanoic acid on the hypoxic rat atria. | 1989 | Arch. Int. Physiol. Biochim. | pmid:2480093 |
| Takagaki A et al. | Isolation and characterization of rat intestinal bacteria involved in biotransformation of (-)-epigallocatechin. | 2014 | Arch. Microbiol. | pmid:24947740 |
| Novokhatny VV et al. | Analysis of ligand binding to kringles 4 and 5 fragments from human plasminogen. | 1989 | Thromb. Res. | pmid:2497544 |
| Sayin S et al. | Enhanced catalysis and enantioselective resolution of racemic naproxen methyl ester by lipase encapsulated within iron oxide nanoparticles coated with calix[8]arene valeric acid complexes. | 2014 | Org. Biomol. Chem. | pmid:25012138 |
| Gołąb K et al. | Improved coating of pancreatic islets with regulatory T cells to create local immunosuppression by using the biotin-polyethylene glycol-succinimidyl valeric acid ester molecule. | 2014 Jul-Aug | Transplant. Proc. | pmid:25131084 |
| Verhoeven E et al. | Pink urine. | 2014 | Clin Toxicol (Phila) | pmid:25233954 |
| De Clerck F et al. | R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivo. | 1989 | Thromb. Haemost. | pmid:2526385 |
| De Clerck F et al. | R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitro. | 1989 | Thromb. Haemost. | pmid:2546278 |
| Erol Öztürk Y et al. | Validation of JWH-018 and its metabolites in blood and urine by UPLC-MS/MS: Monitoring in forensic cases. | 2015 | Forensic Sci. Int. | pmid:25616218 |
| Liang S and Wan C | Carboxylic acid production from brewer's spent grain via mixed culture fermentation. | 2015 | Bioresour. Technol. | pmid:25698409 |
| Kone P et al. | Effect of the combination of monensin and isoacids on rumen fermentation in vitro. | 1989 | J. Dairy Sci. | pmid:2600235 |