Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

Cross Reference

Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dimethylallyl pyrophosphate?

Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dimethylallyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Dimethylallyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dimethylallyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dimethylallyl pyrophosphate

Download all related citations
Per page 10 20 50 100 | Total 520
Authors Title Published Journal PubMed Link
Okada K et al. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. 2008 Plant Cell Physiol. pmid:18303110
pmid:18311542
Phillips MA et al. The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis. 2008 Plant Cell pmid:18319397
pmid:18345677
Kuo CJ et al. Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. 2008 J. Biomed. Biotechnol. pmid:18382620
de Ruyck J and Wouters J Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. 2008 Curr. Protein Pept. Sci. pmid:18393884
Dupont FM Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. 2008 BMC Plant Biol. pmid:18419817
Vandermoten S et al. Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity. 2008 FEBS Lett. pmid:18466770
Docampo R and Moreno SN The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites. 2008 Curr. Pharm. Des. pmid:18473837
Köllner TG et al. Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-beta-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11. 2008 J. Biol. Chem. pmid:18524777
pmid:18651925
Crowhurst RN et al. Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening. 2008 BMC Genomics pmid:18655731
Hirano K et al. Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. 2008 Plant Cell Physiol. pmid:18718932
Xie W et al. Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species. 2008 Phytochemistry pmid:18799172
Chung JA et al. Purification of prenylated proteins by affinity chromatography on cyclodextrin-modified agarose. 2009 Anal. Biochem. pmid:18834849
Alcaíno J et al. Cloning of the cytochrome p450 reductase (crtR) gene and its involvement in the astaxanthin biosynthesis of Xanthophyllomyces dendrorhous. 2008 BMC Microbiol. pmid:18837978
Argout X et al. Towards the understanding of the cocoa transcriptome: Production and analysis of an exhaustive dataset of ESTs of Theobroma cacao L. generated from various tissues and under various conditions. 2008 BMC Genomics pmid:18973681
Ro DK et al. Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. 2008 BMC Biotechnol. pmid:18983675
Ducreux LJ et al. Expression profiling of potato germplasm differentiated in quality traits leads to the identification of candidate flavour and texture genes. 2008 J. Exp. Bot. pmid:18987392
Yin WB et al. Acetylaszonalenin biosynthesis in Neosartorya fischeri. Identification of the biosynthetic gene cluster by genomic mining and functional proof of the genes by biochemical investigation. 2009 J. Biol. Chem. pmid:19001367
Roelofs AJ et al. Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. 2009 Br. J. Haematol. pmid:19016713
Mondego JM et al. A genome survey of Moniliophthora perniciosa gives new insights into Witches' Broom Disease of cacao. 2008 BMC Genomics pmid:19019209
Rekittke I et al. Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. 2008 J. Am. Chem. Soc. pmid:19035630
pmid:19083230
Akashi T et al. Molecular cloning and characterization of a cDNA for pterocarpan 4-dimethylallyltransferase catalyzing the key prenylation step in the biosynthesis of glyceollin, a soybean phytoalexin. 2009 Plant Physiol. pmid:19091879
Tian L et al. Transcript and proteomic analysis of developing white lupin (Lupinus albus L.) roots. 2009 BMC Plant Biol. pmid:19123941
Rasulov B et al. Postillumination isoprene emission: in vivo measurements of dimethylallyldiphosphate pool size and isoprene synthase kinetics in aspen leaves. 2009 Plant Physiol. pmid:19129417
pmid:19149573
Sallaud C et al. A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites. 2009 Plant Cell pmid:19155349
Unno H et al. New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. 2009 J. Biol. Chem. pmid:19158086
Lücker J et al. Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. 2009 BMC Genomics pmid:19171055
Green S et al. Defining the potassium binding region in an apple terpene synthase. 2009 J. Biol. Chem. pmid:19181671
Ganjewala D et al. An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. 2009 Curr Issues Mol Biol pmid:19193963
Tsuruta H et al. High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. 2009 PLoS ONE pmid:19221601
Eberl M et al. A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. 2009 PLoS Pathog. pmid:19229322
Gilg AB et al. Unique animal prenyltransferase with monoterpene synthase activity. 2009 Naturwissenschaften pmid:19277597
pmid:19309001
Ramsden NL et al. A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. 2009 J. Med. Chem. pmid:19320487
Saleh O et al. Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus. 2009 J. Biol. Chem. pmid:19339241
Suzuki M et al. Complete blockage of the mevalonate pathway results in male gametophyte lethality. 2009 J. Exp. Bot. pmid:19363204
Whitaker JW et al. The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. 2009 Genome Biol. pmid:19368726
Wiberley AE et al. Regulation of isoprene emission from poplar leaves throughout a day. 2009 Plant Cell Environ. pmid:19389050
pmid:19398116
Sillero MA et al. Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. 2009 Biochem. Pharmacol. pmid:19414000
pmid:19428716
pmid:19447338
Vinella D et al. Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. 2009 PLoS Genet. pmid:19478995
Correia DV et al. Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. 2009 PLoS ONE pmid:19479075
Schilmiller AL et al. Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19487664
Nieuwenhuizen NJ et al. Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa). 2009 J. Exp. Bot. pmid:19516075
Saikia S and Scott B Functional analysis and subcellular localization of two geranylgeranyl diphosphate synthases from Penicillium paxilli. 2009 Mol. Genet. Genomics pmid:19529962
pmid:19537817
Bohlmann J and Gershenzon J Old substrates for new enzymes of terpenoid biosynthesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19553206
pmid:19557032
Rubio-Aliaga I et al. Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. 2009 PLoS ONE pmid:19562077
Gräwert T et al. Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. 2009 Angew. Chem. Int. Ed. Engl. pmid:19569147
pmid:19575586
Marks MD et al. Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. 2009 J. Exp. Bot. pmid:19581347
Mann FM et al. Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis. 2009 J. Am. Chem. Soc. pmid:19583202
pmid:19583210
pmid:19615911
Vandermoten S et al. New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition. 2009 Cell. Mol. Life Sci. pmid:19633972
Rotter A et al. Gene expression profiling in susceptible interaction of grapevine with its fungal pathogen Eutypa lata: extending MapMan ontology for grapevine. 2009 BMC Plant Biol. pmid:19656401
Jauhiainen M et al. Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19665949
Majumdar A et al. Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using (1)H-(31)P-(31)P correlation NMR spectroscopy. 2009 Mol Biosyst pmid:19668858
de Souza W and Rodrigues JC Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. 2009 Interdiscip Perspect Infect Dis pmid:19680554
Metzger U et al. The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19706516
pmid:19708647
Alagna F et al. Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. 2009 BMC Genomics pmid:19709400
Luk LY and Tanner ME Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction. 2009 J. Am. Chem. Soc. pmid:19743851
pmid:19762440
Morrone D et al. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. 2010 Appl. Microbiol. Biotechnol. pmid:19777230
Wang W et al. Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing. 2009 BMC Genomics pmid:19818120
Yazaki K et al. Prenylation of aromatic compounds, a key diversification of plant secondary metabolites. Phytochemistry pmid:19819506
Cann AF and Liao JC Pentanol isomer synthesis in engineered microorganisms. 2010 Appl. Microbiol. Biotechnol. pmid:19859707
pmid:19878958
Tritsch D et al. Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures. 2010 FEBS Lett. pmid:19903472
Xu Q et al. Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. 2009 BMC Genomics pmid:19922663
Chen M and Poulter CD Characterization of thermophilic archaeal isopentenyl phosphate kinases. 2010 Biochemistry pmid:19928876
Zhang J et al. AtSOFL1 and AtSOFL2 act redundantly as positive modulators of the endogenous content of specific cytokinins in Arabidopsis. 2009 PLoS ONE pmid:20011053
Jawaid S et al. Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). 2009 PLoS ONE pmid:20011597
Orlova I et al. The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. 2009 Plant Cell pmid:20028839
Dellomonaco C et al. The path to next generation biofuels: successes and challenges in the era of synthetic biology. 2010 Microb. Cell Fact. pmid:20089184
Iriti M and Faoro F Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. 2009 Int J Mol Sci pmid:20111684
Lim L and McFadden GI The evolution, metabolism and functions of the apicoplast. 2010 Philos. Trans. R. Soc. Lond., B, Biol. Sci. pmid:20124342
Trost E et al. Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion. 2010 BMC Genomics pmid:20137072
Arana L et al. Ceramide and ceramide 1-phosphate in health and disease. 2010 Lipids Health Dis pmid:20137073
Chang TH et al. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. 2010 Plant Cell pmid:20139160
Hawari AH and Mohamed-Hussein ZA Simulation of a Petri net-based model of the terpenoid biosynthesis pathway. 2010 BMC Bioinformatics pmid:20144236
Noel JP et al. Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. 2010 ACS Chem. Biol. pmid:20175559
Ibrahim MA et al. Elevation of night-time temperature increases terpenoid emissions from Betula pendula and Populus tremula. 2010 J. Exp. Bot. pmid:20181662
Narayanasamy P et al. Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. 2010 Chem. Biol. pmid:20189102
Kalinowska-Tłuścik J et al. A triclinic crystal form of Escherichia coli 4-diphosphocytidyl-2C-methyl-D-erythritol kinase and reassessment of the quaternary structure. 2010 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:20208151
pmid:20213667
Takahashi S et al. Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. 2010 J. Bacteriol. pmid:20348259
Haug-Schifferdecker E et al. A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction. 2010 J. Biol. Chem. pmid:20351110
Aw T et al. Functional genomics of mountain pine beetle (Dendroctonus ponderosae) midguts and fat bodies. 2010 BMC Genomics pmid:20353591
Dellas N and Noel JP Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. 2010 ACS Chem. Biol. pmid:20392112
Sadre R et al. Catalytic reactions of the homogentisate prenyl transferase involved in plastoquinone-9 biosynthesis. 2010 J. Biol. Chem. pmid:20400515
Mabanglo MF et al. X-ray structures of isopentenyl phosphate kinase. 2010 ACS Chem. Biol. pmid:20402538