Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

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Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dimethylallyl pyrophosphate?

Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dimethylallyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

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PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dimethylallyl pyrophosphate?

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What functions are associated with Dimethylallyl pyrophosphate?


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What lipids are associated with Dimethylallyl pyrophosphate?

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What genes are associated with Dimethylallyl pyrophosphate?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dimethylallyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

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All references with Dimethylallyl pyrophosphate

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Authors Title Published Journal PubMed Link
Sharon C et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. 2015 Oncotarget pmid:25895029
Wollinsky B et al. Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1. 2012 Org. Biomol. Chem. pmid:23090579
Barkley SJ et al. Proton exchange in type II isopentenyl diphosphate isomerase. 2004 Org. Lett. pmid:15606125
Xiao Y et al. Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues. 2011 Org. Lett. pmid:21981393
Kao CL et al. Stereochemical analysis of isopentenyl diphosphate isomerase type II from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. 2005 Org. Lett. pmid:16321020
Leyes AE et al. Biosynthesis of isoprenoids in Escherichia coli: stereochemistry of the reaction catalyzed by farnesyl diphosphate synthase. 1999 Org. Lett. pmid:10825960
Ueno A et al. Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. 2013 Parasitol. Int. pmid:23276703
Türsen U Pathophysiology of the Behçet's Disease. 2012 Patholog Res Int pmid:21977335
Wen W and Yu R Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. 2011 Pharmacogn Rev pmid:22279377
Lim L and McFadden GI The evolution, metabolism and functions of the apicoplast. 2010 Philos. Trans. R. Soc. Lond., B, Biol. Sci. pmid:20124342
Xie W et al. Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species. 2008 Phytochemistry pmid:18799172
Green S et al. Unusual features of a recombinant apple alpha-farnesene synthase. 2007 Phytochemistry pmid:17140613
Margl L et al. Biosynthesis of benzofuran derivatives in root cultures of Tagetes patula via phenylalanine and 1-deoxy-D-xylulose 5-phosphate. 2005 Phytochemistry pmid:15845407
Yazaki K et al. Prenylation of aromatic compounds, a key diversification of plant secondary metabolites. Phytochemistry pmid:19819506
Schmidt A and Gershenzon J Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). 2008 Phytochemistry pmid:17673268
Carter OA et al. Monoterpene biosynthesis pathway construction in Escherichia coli. 2003 Phytochemistry pmid:12943759
Rosenstiel TN et al. Induction of poplar leaf nitrate reductase: a test of extrachloroplastic control of isoprene emission rate. 2004 Jan-Feb Plant Biol (Stuttg) pmid:15095130
Orlova I et al. The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. 2009 Plant Cell pmid:20028839
Chang TH et al. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. 2010 Plant Cell pmid:20139160
Sallaud C et al. A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites. 2009 Plant Cell pmid:19155349
Phillips MA et al. The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis. 2008 Plant Cell pmid:18319397
Guevara-García A et al. Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscriptional regulation of the methyl-D-erythritol 4-phosphate pathway. 2005 Plant Cell pmid:15659625
Wiberley AE et al. Regulation of isoprene emission in Populus trichocarpa leaves subjected to changing growth temperature. 2008 Plant Cell Environ. pmid:17996012
Rasulov B et al. Competition between isoprene emission and pigment synthesis during leaf development in aspen. 2014 Plant Cell Environ. pmid:24033429
Wiberley AE et al. Regulation of isoprene emission from poplar leaves throughout a day. 2009 Plant Cell Environ. pmid:19389050
Okada K et al. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. 2008 Plant Cell Physiol. pmid:18303110
Hirano K et al. Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. 2008 Plant Cell Physiol. pmid:18718932
Masferrer A et al. Overexpression of Arabidopsis thaliana farnesyl diphosphate synthase (FPS1S) in transgenic Arabidopsis induces a cell death/senescence-like response and reduced cytokinin levels. 2002 Plant J. pmid:12000449
Behnke K et al. Transgenic, non-isoprene emitting poplars don't like it hot. 2007 Plant J. pmid:17587235
Gonzales-Vigil E et al. Evolution of TPS20-related terpene synthases influences chemical diversity in the glandular trichomes of the wild tomato relative Solanum habrochaites. 2012 Plant J. pmid:22563774
Kishi-Kaboshi M et al. A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis. 2010 Plant J. pmid:20525005
Botella-Pavía P et al. Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. 2004 Plant J. pmid:15447646
Angaman DM et al. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. 2012 Plant Methods pmid:22243738
Manzano D et al. Overexpression of farnesyl diphosphate synthase in Arabidopsis mitochondria triggers light-dependent lesion formation and alters cytokinin homeostasis. 2006 Plant Mol. Biol. pmid:16786301
Phillips MA et al. Functional identification and differential expression of 1-deoxy-D-xylulose 5-phosphate synthase in induced terpenoid resin formation of Norway spruce (Picea abies). 2007 Plant Mol. Biol. pmid:17687625
Bleeker PM et al. RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes. 2011 Plant Mol. Biol. pmid:21818683
Behnke K et al. RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. 2010 Plant Mol. Biol. pmid:20526857
Schmidt A et al. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). 2011 Plant Mol. Biol. pmid:22002747
Delourme D et al. Cloning of an Arabidopsis thaliana cDNA coding for farnesyl diphosphate synthase by functional complementation in yeast. 1994 Plant Mol. Biol. pmid:7858223
Li Z et al. Effect of temperature on postillumination isoprene emission in oak and poplar. 2011 Plant Physiol. pmid:21177471
Rasulov B et al. Postillumination isoprene emission: in vivo measurements of dimethylallyldiphosphate pool size and isoprene synthase kinetics in aspen leaves. 2009 Plant Physiol. pmid:19129417
Zhao P et al. Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. 2003 Plant Physiol. pmid:14551337
Nogués I et al. Dimethylallyl diphosphate and geranyl diphosphate pools of plant species characterized by different isoprenoid emissions. 2006 Plant Physiol. pmid:16461390
Schnee C et al. The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. 2002 Plant Physiol. pmid:12481088
Akashi T et al. Molecular cloning and characterization of a cDNA for pterocarpan 4-dimethylallyltransferase catalyzing the key prenylation step in the biosynthesis of glyceollin, a soybean phytoalexin. 2009 Plant Physiol. pmid:19091879
Yang T et al. A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway. 2016 Plant Physiol. pmid:27356974
George GM et al. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. 2010 Plant Physiol. pmid:20605913
Galichet A et al. Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. 2008 Plant Physiol. pmid:18184738
Schilmiller AL et al. Studies of a biochemical factory: tomato trichome deep expressed sequence tag sequencing and proteomics. 2010 Plant Physiol. pmid:20431087
Jassbi AR et al. Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm. 2008 Plant Physiol. pmid:17965175
Loivamäki M et al. Arabidopsis, a model to study biological functions of isoprene emission? 2007 Plant Physiol. pmid:17468218
Muñoz-Bertomeu J et al. Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. 2006 Plant Physiol. pmid:16980564
Cervantes-Cervantes M et al. Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. 2006 Plant Physiol. pmid:16581875
Mayrhofer S et al. Diurnal and seasonal variation of isoprene biosynthesis-related genes in grey poplar leaves. 2005 Plant Physiol. pmid:16126852
Sharkey TD et al. Evolution of the isoprene biosynthetic pathway in kudzu. 2005 Plant Physiol. pmid:15653811
Sasaki K et al. Cloning and characterization of naringenin 8-prenyltransferase, a flavonoid-specific prenyltransferase of Sophora flavescens. 2008 Plant Physiol. pmid:18218974
Rosenstiel TN et al. Differential accumulation of dimethylallyl diphosphate in leaves and needles of isoprene- and methylbutenol-emitting and nonemitting species. 2002 Plant Physiol. pmid:12114581
Wolfertz M et al. Rapid regulation of the methylerythritol 4-phosphate pathway during isoprene synthesis. 2004 Plant Physiol. pmid:15286290
Page JE et al. Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing. 2004 Plant Physiol. pmid:15064370
Lange BM et al. Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. 2001 Plant Physiol. pmid:11553758
Ghirardo A et al. Metabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene. 2014 Plant Physiol. pmid:24590857
Loreto F et al. 13C labeling reveals chloroplastic and extrachloroplastic pools of dimethylallyl pyrophosphate and their contribution to isoprene formation. 2004 Plant Physiol. pmid:15286296
Clastre M et al. Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. 2011 Plant Signal Behav pmid:22080790
Okada K et al. Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. 2002 Planta pmid:12029484
Zeidler J and Lichtenthaler HK Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. 2001 Planta pmid:11469599
Wu S et al. Engineering triterpene metabolism in tobacco. 2012 Planta pmid:22729821
Arimura G et al. Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. 2008 Planta pmid:17924138
Suzuki N et al. Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. 2012 Planta pmid:22729820
Sabehi G et al. New insights into metabolic properties of marine bacteria encoding proteorhodopsins. 2005 PLoS Biol. pmid:16008504
Nair SC and Striepen B What do human parasites do with a chloroplast anyway? 2011 PLoS Biol. pmid:21912515
Yeh E and DeRisi JL Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum. 2011 PLoS Biol. pmid:21912516
Vinella D et al. Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. 2009 PLoS Genet. pmid:19478995
Brilli F et al. Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction "time-of-flight" mass spectrometry (PTR-TOF). 2011 PLoS ONE pmid:21637822
Yang J et al. Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. 2012 PLoS ONE pmid:22558074
Atsbaha Zebelo S et al. Chrysolina herbacea modulates terpenoid biosynthesis of Mentha aquatica L. 2011 PLoS ONE pmid:21408066
Tsang A et al. Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. 2011 PLoS ONE pmid:21694781
Chen X et al. Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. 2013 PLoS ONE pmid:24278153
Jawaid S et al. Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). 2009 PLoS ONE pmid:20011597
Trowbridge AM et al. Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations. 2012 PLoS ONE pmid:22384238
Bonitz T et al. Evolutionary relationships of microbial aromatic prenyltransferases. 2011 PLoS ONE pmid:22140437
Lu J et al. Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules. 2011 PLoS ONE pmid:21935360
Tsuruta H et al. High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. 2009 PLoS ONE pmid:19221601
Hao da C et al. The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing. 2011 PLoS ONE pmid:21731678
Nickerson ML et al. UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy. 2010 PLoS ONE pmid:20505825
Baumeister S et al. Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. 2011 PLoS ONE pmid:21573242
Zhang J et al. AtSOFL1 and AtSOFL2 act redundantly as positive modulators of the endogenous content of specific cytokinins in Arabidopsis. 2009 PLoS ONE pmid:20011053
Ghirardo A et al. Biogenic volatile organic compound and respiratory CO2 emissions after 13C-labeling: online tracing of C translocation dynamics in poplar plants. 2011 PLoS ONE pmid:21387007
Rubio-Aliaga I et al. Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. 2009 PLoS ONE pmid:19562077
Correia DV et al. Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. 2009 PLoS ONE pmid:19479075
Velasco R et al. A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. 2007 PLoS ONE pmid:18094749
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Tidten-Luksch N et al. IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. 2012 PLoS ONE pmid:22563402
Banerjee A et al. Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. 2016 PLoS ONE pmid:27548482
Fox DT et al. Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. 2014 PLoS ONE pmid:24751777
Odom AR Five questions about non-mevalonate isoprenoid biosynthesis. 2011 PLoS Pathog. pmid:22216001
Davey MS et al. Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. 2011 PLoS Pathog. pmid:21589907
Eberl M et al. A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. 2009 PLoS Pathog. pmid:19229322
Perrin RM et al. Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. 2007 PLoS Pathog. pmid:17432932
Goto T et al. Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. 2010 PPAR Res pmid:20613991
Kuzuyama T and Seto H Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. 2012 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:22450534