MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ramsden NL et al. | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. | 2009 | J. Med. Chem. | pmid:19320487 |
Lee M et al. | Biosynthesis of isoprenoids: crystal structure of the [4Fe-4S] cluster protein IspG. | 2010 | J. Mol. Biol. | pmid:20932974 |
Köksal M et al. | Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission. | 2010 | J. Mol. Biol. | pmid:20624401 |
Span I et al. | Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. | 2012 | J. Mol. Biol. | pmid:22137895 |
Xie W et al. | Structure of tRNA dimethylallyltransferase: RNA modification through a channel. | 2007 | J. Mol. Biol. | pmid:17292915 |
Heaps NA and Poulter CD | Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase. | 2011 | J. Org. Chem. | pmid:21344952 |
Thulasiram HV et al. | Synthesis of deuterium-labeled derivatives of dimethylallyl diphosphate. | 2006 | J. Org. Chem. | pmid:16468838 |
Nordqvist A et al. | Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors. | 2011 | J. Org. Chem. | pmid:21936546 |
Phan RM and Poulter CD | Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. | 2001 | J. Org. Chem. | pmid:11578224 |
Krasutsky SG et al. | Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. | 2014 | J. Org. Chem. | pmid:25184438 |