Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

Cross Reference

Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dimethylallyl pyrophosphate?

Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dimethylallyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Dimethylallyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dimethylallyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dimethylallyl pyrophosphate

Download all related citations
Per page 10 20 50 100 | Total 520
Authors Title Published Journal PubMed Link
Ramsden NL et al. A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. 2009 J. Med. Chem. pmid:19320487
Lee M et al. Biosynthesis of isoprenoids: crystal structure of the [4Fe-4S] cluster protein IspG. 2010 J. Mol. Biol. pmid:20932974
Köksal M et al. Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission. 2010 J. Mol. Biol. pmid:20624401
Span I et al. Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. 2012 J. Mol. Biol. pmid:22137895
Xie W et al. Structure of tRNA dimethylallyltransferase: RNA modification through a channel. 2007 J. Mol. Biol. pmid:17292915
Heaps NA and Poulter CD Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase. 2011 J. Org. Chem. pmid:21344952
Thulasiram HV et al. Synthesis of deuterium-labeled derivatives of dimethylallyl diphosphate. 2006 J. Org. Chem. pmid:16468838
Nordqvist A et al. Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors. 2011 J. Org. Chem. pmid:21936546
Phan RM and Poulter CD Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. 2001 J. Org. Chem. pmid:11578224
Krasutsky SG et al. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. 2014 J. Org. Chem. pmid:25184438
Thabet I et al. The subcellular localization of periwinkle farnesyl diphosphate synthase provides insight into the role of peroxisome in isoprenoid biosynthesis. 2011 J. Plant Physiol. pmid:21872968
Sun Z et al. Can the capacity for isoprene emission acclimate to environmental modifications during autumn senescence in temperate deciduous tree species Populus tremula? 2012 J. Plant Res. pmid:21584787
Arana L et al. Ceramide and ceramide 1-phosphate in health and disease. 2010 Lipids Health Dis pmid:20137073
Misawa N Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. 2011 Mar Drugs pmid:21673887
Dunne MR et al. Preferential Th1 cytokine profile of phosphoantigen-stimulated human Vγ9Vδ2 T cells. 2010 Mediators Inflamm. pmid:21403900
Cassera MB et al. Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. 2007 Mem. Inst. Oswaldo Cruz pmid:17568945
Hasunuma T et al. Metabolic engineering by plastid transformation as a strategy to modulate isoprenoid yield in plants. 2010 Methods Mol. Biol. pmid:20552454
Seeger K et al. The biosynthetic genes for prenylated phenazines are located at two different chromosomal loci of Streptomyces cinnamonensis DSM 1042. 2011 Microb Biotechnol pmid:21342470
Jang HJ et al. Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. 2011 Microb. Cell Fact. pmid:21801353
Lemuth K et al. Engineering of a plasmid-free Escherichia coli strain for improved in vivo biosynthesis of astaxanthin. 2011 Microb. Cell Fact. pmid:21521516