| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hemmi H et al. | An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase. | 2003 | Eur. J. Biochem. | pmid:12752438 |
| Liang PH et al. | Structure, mechanism and function of prenyltransferases. | 2002 | Eur. J. Biochem. | pmid:12135472 |
| Kabelitz D | Human γδ T lymphocytes for immunotherapeutic strategies against cancer. | 2010 | F1000 Med Rep | pmid:20948839 |
| Heider SA et al. | IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum. | 2014 | FEBS J. | pmid:25181035 |
| Mann FM et al. | Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. | 2011 | FEBS Lett. | pmid:21237161 |
| Wolff M et al. | Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. | 2003 | FEBS Lett. | pmid:12706830 |
| Tritsch D et al. | Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures. | 2010 | FEBS Lett. | pmid:19903472 |
| Vitali A et al. | Chalcone dimethylallyltransferase from Morus nigra cell cultures. Substrate specificity studies. | 2004 | FEBS Lett. | pmid:14741337 |
| Chu HM et al. | Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates. | 2010 | FEBS Lett. | pmid:20807533 |
| Vandermoten S et al. | Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity. | 2008 | FEBS Lett. | pmid:18466770 |
| Altincicek B et al. | LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. | 2002 | FEBS Lett. | pmid:12482608 |
| Miller B et al. | A Synechococcus leopoliensis SAUG 1402-1 operon harboring the 1-deoxyxylulose 5-phosphate synthase gene and two additional open reading frames is functionally involved in the dimethylallyl diphosphate synthesis. | 1999 | FEBS Lett. | pmid:10556522 |
| RodrÃguez-Concepción M et al. | Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. | 2000 | FEBS Lett. | pmid:10818234 |
| Ershov Y et al. | Isopentenyl diphosphate isomerase deficiency in Synechocystis sp. strain PCC6803. | 2000 | FEBS Lett. | pmid:10818236 |
| Hirooka K et al. | The role of histidine-114 of Ssulfolobus acidocaldarius geranylgeranyl diphosphate synthase in chain-length determination. | 2000 | FEBS Lett. | pmid:10984617 |
| Miller B et al. | Functional involvement of a deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. | 2000 | FEBS Lett. | pmid:11007968 |
| Lamsen EN and Atsumi S | Recent progress in synthetic biology for microbial production of C3-C10 alcohols. | 2012 | Front Microbiol | pmid:22701113 |
| Hümbelin M et al. | Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. | 2002 | Gene | pmid:12384294 |
| Trapp SC and Croteau RB | Genomic organization of plant terpene synthases and molecular evolutionary implications. | 2001 | Genetics | pmid:11404343 |
| Vissa VD and Brennan PJ | The genome of Mycobacterium leprae: a minimal mycobacterial gene set. | 2001 | Genome Biol. | pmid:11532219 |
| Maurer-Stroh S and Eisenhaber F | Refinement and prediction of protein prenylation motifs. | 2005 | Genome Biol. | pmid:15960807 |
| Maurer-Stroh S et al. | Protein prenyltransferases. | 2003 | Genome Biol. | pmid:12702202 |
| Wille A et al. | Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. | 2004 | Genome Biol. | pmid:15535868 |
| Whitaker JW et al. | The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. | 2009 | Genome Biol. | pmid:19368726 |
| Sireci G et al. | Patterns of phosphoantigen stimulation of human Vgamma9/Vdelta2 T cell clones include Th0 cytokines. | 1997 | Hum. Immunol. | pmid:9475336 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Amslinger S et al. | Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. | 2007 | Immunobiology | pmid:17270709 |
| Sen SE et al. | Juvenile hormone biosynthesis in M. sexta: substrate specificity of insect prenyltransferase utilizing homologous diphosphate analogs. | 2006 | Insect Biochem. Mol. Biol. | pmid:17046596 |
| Diaz ME et al. | Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. | 2012 | Insect Biochem. Mol. Biol. | pmid:22782071 |
| Song AA et al. | Functional expression of an orchid fragrance gene in Lactococcus lactis. | 2012 | Int J Mol Sci | pmid:22408409 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
| de Souza W and Rodrigues JC | Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | 2009 | Interdiscip Perspect Infect Dis | pmid:19680554 |
| Muraguchi T et al. | Polished rice as natural sources of cancer-preventing geranylgeranoic acid. | 2011 | J Clin Biochem Nutr | pmid:21765600 |
| Hussain MS et al. | Current approaches toward production of secondary plant metabolites. | 2012 | J Pharm Bioallied Sci | pmid:22368394 |
| Luk LY and Tanner ME | Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction. | 2009 | J. Am. Chem. Soc. | pmid:19743851 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Johnston JB et al. | Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues. | 2007 | J. Am. Chem. Soc. | pmid:17547410 |
| Wu Z et al. | Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate. | 2005 | J. Am. Chem. Soc. | pmid:16332094 |
| Jost M et al. | Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity. | 2010 | J. Am. Chem. Soc. | pmid:21105662 |
| Heaps NA and Poulter CD | Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism. | 2011 | J. Am. Chem. Soc. | pmid:22047048 |
| Thulasiram HV and Poulter CD | Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. | 2006 | J. Am. Chem. Soc. | pmid:17147392 |
| Faraldos JA et al. | Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. | 2012 | J. Am. Chem. Soc. | pmid:23214943 |
| Thibodeaux CJ et al. | Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. | 2010 | J. Am. Chem. Soc. | pmid:20593767 |
| Mann FM et al. | Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis. | 2009 | J. Am. Chem. Soc. | pmid:19583202 |
| Jonnalagadda V et al. | Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. | 2012 | J. Am. Chem. Soc. | pmid:22471428 |
| Gray CR et al. | Studies on the biosynthesis of asperparaline A: origin of the spirosuccinimde ring system. | 2003 | J. Am. Chem. Soc. | pmid:14640629 |
| Takahashi S et al. | Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. | 2010 | J. Bacteriol. | pmid:20348259 |
| Nakatani H et al. | Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae. | 2012 | J. Bacteriol. | pmid:22505674 |
| Cunningham FX et al. | Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. | 2000 | J. Bacteriol. | pmid:11004185 |