| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mann FM et al. | Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. | 2011 | FEBS Lett. | pmid:21237161 |
| Wolff M et al. | Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. | 2003 | FEBS Lett. | pmid:12706830 |
| Vitali A et al. | Chalcone dimethylallyltransferase from Morus nigra cell cultures. Substrate specificity studies. | 2004 | FEBS Lett. | pmid:14741337 |
| Chu HM et al. | Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates. | 2010 | FEBS Lett. | pmid:20807533 |
| Altincicek B et al. | LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. | 2002 | FEBS Lett. | pmid:12482608 |
| Miller B et al. | Functional involvement of a deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. | 2000 | FEBS Lett. | pmid:11007968 |
| Heider SA et al. | IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum. | 2014 | FEBS J. | pmid:25181035 |
| Kabelitz D | Human γδ T lymphocytes for immunotherapeutic strategies against cancer. | 2010 | F1000 Med Rep | pmid:20948839 |
| Yamashita S et al. | Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae. | 2004 | Eur. J. Biochem. | pmid:15009187 |
| Laupitz R et al. | Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. | 2004 | Eur. J. Biochem. | pmid:15206931 |
| Hemmi H et al. | An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase. | 2003 | Eur. J. Biochem. | pmid:12752438 |
| Liang PH et al. | Structure, mechanism and function of prenyltransferases. | 2002 | Eur. J. Biochem. | pmid:12135472 |
| Hirooka K et al. | Mechanism of product chain length determination for heptaprenyl diphosphate synthase from Bacillus stearothermophilus. | 2000 | Eur. J. Biochem. | pmid:10880976 |
| Tachibana A et al. | Novel prenyltransferase gene encoding farnesylgeranyl diphosphate synthase from a hyperthermophilic archaeon, Aeropyrum pernix. Molecularevolution with alteration in product specificity. | 2000 | Eur. J. Biochem. | pmid:10632701 |
| Wiley JD et al. | Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum. | 2015 | Eukaryotic Cell | pmid:25446055 |
| Durbecq V et al. | Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. | 2001 | EMBO J. | pmid:11285217 |
| de Ruyck J and Wouters J | Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. | 2008 | Curr. Protein Pept. Sci. | pmid:18393884 |
| Docampo R and Moreno SN | The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites. | 2008 | Curr. Pharm. Des. | pmid:18473837 |
| Hunter WN | Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. | 2011 | Curr Top Med Chem | pmid:21619509 |
| Chang WC et al. | Current development in isoprenoid precursor biosynthesis and regulation. | 2013 | Curr Opin Chem Biol | pmid:23891475 |