| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
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| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Richard SB et al. | Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. | 2002 | J. Biol. Chem. | pmid:11786530 |
| Yu X et al. | Biochemical characterization of indole prenyltransferases: filling the last gap of prenylation positions by a 5-dimethylallyltryptophan synthase from Aspergillus clavatus. | 2012 | J. Biol. Chem. | pmid:22123822 |
| Guo RT et al. | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. | 2005 | J. Biol. Chem. | pmid:15788389 |
| Banerjee A et al. | Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway. | 2013 | J. Biol. Chem. | pmid:23612965 |
| Köllner TG et al. | Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-beta-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11. | 2008 | J. Biol. Chem. | pmid:18524777 |
| Sadre R et al. | Catalytic reactions of the homogentisate prenyl transferase involved in plastoquinone-9 biosynthesis. | 2010 | J. Biol. Chem. | pmid:20400515 |
| Gray DW et al. | Biochemical characterization and homology modeling of methylbutenol synthase and implications for understanding hemiterpene synthase evolution in plants. | 2011 | J. Biol. Chem. | pmid:21504898 |
| Saleh O et al. | Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus. | 2009 | J. Biol. Chem. | pmid:19339241 |
| Light DR and Dennis MS | Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis. | 1989 | J. Biol. Chem. | pmid:2808388 |
| Yin WB et al. | Acetylaszonalenin biosynthesis in Neosartorya fischeri. Identification of the biosynthetic gene cluster by genomic mining and functional proof of the genes by biochemical investigation. | 2009 | J. Biol. Chem. | pmid:19001367 |
| Light DR et al. | Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity. | 1989 | J. Biol. Chem. | pmid:2808389 |
| Leung HC et al. | Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12. | 1997 | J. Biol. Chem. | pmid:9148919 |
| Takei K et al. | Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana. | 2001 | J. Biol. Chem. | pmid:11313355 |
| Kasahara H et al. | Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. | 2004 | J. Biol. Chem. | pmid:14726522 |
| Fan A et al. | Site-directed mutagenesis switching a dimethylallyl tryptophan synthase to a specific tyrosine C3-prenylating enzyme. | 2015 | J. Biol. Chem. | pmid:25477507 |
| Matsumura Y et al. | The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. | 2007 | J. Biochem. | pmid:17846065 |
| Fujisaki S et al. | Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. | 2005 | J. Biochem. | pmid:15809342 |
| Takahashi S et al. | Biochemical characterization of a novel indole prenyltransferase from Streptomyces sp. SN-593. | 2010 | J. Bacteriol. | pmid:20348259 |
| Nakatani H et al. | Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae. | 2012 | J. Bacteriol. | pmid:22505674 |
| Altincicek B et al. | GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. | 2001 | J. Bacteriol. | pmid:11274098 |
| Ershov YV et al. | Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. | 2002 | J. Bacteriol. | pmid:12193620 |
| Cunningham FX et al. | Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. | 2000 | J. Bacteriol. | pmid:11004185 |
| Poliquin K et al. | Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. | 2004 | J. Bacteriol. | pmid:15231801 |
| Luk LY and Tanner ME | Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction. | 2009 | J. Am. Chem. Soc. | pmid:19743851 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Johnston JB et al. | Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues. | 2007 | J. Am. Chem. Soc. | pmid:17547410 |
| Wu Z et al. | Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate. | 2005 | J. Am. Chem. Soc. | pmid:16332094 |
| Jost M et al. | Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity. | 2010 | J. Am. Chem. Soc. | pmid:21105662 |
| Heaps NA and Poulter CD | Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism. | 2011 | J. Am. Chem. Soc. | pmid:22047048 |
| Thulasiram HV and Poulter CD | Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. | 2006 | J. Am. Chem. Soc. | pmid:17147392 |
| Faraldos JA et al. | Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. | 2012 | J. Am. Chem. Soc. | pmid:23214943 |
| Thibodeaux CJ et al. | Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. | 2010 | J. Am. Chem. Soc. | pmid:20593767 |
| Mann FM et al. | Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis. | 2009 | J. Am. Chem. Soc. | pmid:19583202 |
| Jonnalagadda V et al. | Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. | 2012 | J. Am. Chem. Soc. | pmid:22471428 |
| Gray CR et al. | Studies on the biosynthesis of asperparaline A: origin of the spirosuccinimde ring system. | 2003 | J. Am. Chem. Soc. | pmid:14640629 |
| Hussain MS et al. | Current approaches toward production of secondary plant metabolites. | 2012 | J Pharm Bioallied Sci | pmid:22368394 |
| Muraguchi T et al. | Polished rice as natural sources of cancer-preventing geranylgeranoic acid. | 2011 | J Clin Biochem Nutr | pmid:21765600 |
| de Souza W and Rodrigues JC | Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | 2009 | Interdiscip Perspect Infect Dis | pmid:19680554 |
| Emma F et al. | Renal mitochondrial cytopathies. | 2011 | Int J Nephrol | pmid:21811680 |
| Song AA et al. | Functional expression of an orchid fragrance gene in Lactococcus lactis. | 2012 | Int J Mol Sci | pmid:22408409 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Sen SE et al. | Juvenile hormone biosynthesis in M. sexta: substrate specificity of insect prenyltransferase utilizing homologous diphosphate analogs. | 2006 | Insect Biochem. Mol. Biol. | pmid:17046596 |
| Diaz ME et al. | Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. | 2012 | Insect Biochem. Mol. Biol. | pmid:22782071 |
| Amslinger S et al. | Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. | 2007 | Immunobiology | pmid:17270709 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Sireci G et al. | Patterns of phosphoantigen stimulation of human Vgamma9/Vdelta2 T cell clones include Th0 cytokines. | 1997 | Hum. Immunol. | pmid:9475336 |
| Vissa VD and Brennan PJ | The genome of Mycobacterium leprae: a minimal mycobacterial gene set. | 2001 | Genome Biol. | pmid:11532219 |
| Maurer-Stroh S and Eisenhaber F | Refinement and prediction of protein prenylation motifs. | 2005 | Genome Biol. | pmid:15960807 |
| Maurer-Stroh S et al. | Protein prenyltransferases. | 2003 | Genome Biol. | pmid:12702202 |
| Wille A et al. | Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. | 2004 | Genome Biol. | pmid:15535868 |