MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dupont FM | Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. | 2008 | BMC Plant Biol. | pmid:18419817 |
Sgraja T et al. | Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. | 2007 | BMC Struct. Biol. | pmid:17397541 |
Buetow L et al. | The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. | 2007 | BMC Struct. Biol. | pmid:17956607 |
Boghigian BA et al. | Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design. | 2010 | BMC Syst Biol | pmid:20416071 |
Meier S et al. | A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. | 2011 | BMC Syst Biol | pmid:21595952 |
Riebeling C et al. | The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. | 2002 | Br. J. Cancer | pmid:12177810 |
Roelofs AJ et al. | Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. | 2009 | Br. J. Haematol. | pmid:19016713 |
Bang S et al. | Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation. | 2012 | Br. J. Pharmacol. | pmid:22300296 |
Fowler DW et al. | Mycobacteria activate γδ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy. | 2012 | Cancer Immunol. Immunother. | pmid:22002242 |
Vandermoten S et al. | New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition. | 2009 | Cell. Mol. Life Sci. | pmid:19633972 |