MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Szkopińska A and Płochocka D | Farnesyl diphosphate synthase; regulation of product specificity. | 2005 | Acta Biochim. Pol. | pmid:15827605 |
Wanke M et al. | Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. | 2001 | Acta Biochim. Pol. | pmid:11833775 |
Walsh CT | Revealing coupling patterns in isoprenoid alkylation biocatalysis. | 2007 | ACS Chem. Biol. | pmid:17518430 |
Rudolf JD and Poulter CD | Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives. | 2013 | ACS Chem. Biol. | pmid:24083562 |
Bitok JK and Meyers CF | 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity. | 2012 | ACS Chem. Biol. | pmid:22839733 |
Dellas N and Noel JP | Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. | 2010 | ACS Chem. Biol. | pmid:20392112 |
Mabanglo MF et al. | X-ray structures of isopentenyl phosphate kinase. | 2010 | ACS Chem. Biol. | pmid:20402538 |
Noel JP et al. | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. | 2010 | ACS Chem. Biol. | pmid:20175559 |
Oldfield E | Targeting isoprenoid biosynthesis for drug discovery: bench to bedside. | 2010 | Acc. Chem. Res. | pmid:20560544 |
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