| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mahmoud SS and Croteau RB | Strategies for transgenic manipulation of monoterpene biosynthesis in plants. | 2002 | Trends Plant Sci. | pmid:12167332 |
| Eisenreich W et al. | Deoxyxylulose phosphate pathway to terpenoids. | 2001 | Trends Plant Sci. | pmid:11173292 |
| Tijerino A et al. | Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | 2011 | Toxins (Basel) | pmid:22069764 |
| Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
| Yadav VR et al. | Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. | 2010 | Toxins (Basel) | pmid:22069560 |
| Takagi M et al. | [Overlooked targets for the development of antibacterial and antimalarial drugs and herbicides: diverse biosynthetic systems for the isoprene units]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:11808197 |
| Kakimoto T | [Cytokinin]. | 2002 | Tanpakushitsu Kakusan Koso | pmid:12357630 |
| Hemmi H | [Unique flavoenzyme: type 2 isopentenyl diphosphate isomerase]. | 2011 | Seikagaku | pmid:21626882 |
| Liu T and Khosla C | Chemistry. A balancing act for Taxol precursor pathways in E. coli. | 2010 | Science | pmid:20929799 |
| Ajikumar PK et al. | Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. | 2010 | Science | pmid:20929806 |
| Christianson DW | Chemistry. Roots of biosynthetic diversity. | 2007 | Science | pmid:17412944 |
| Umeda T et al. | Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum. | 2011 | Sci Rep | pmid:22355528 |
| Fischer MJ et al. | Identification of a lysine residue important for the catalytic activity of yeast farnesyl diphosphate synthase. | 2011 | Protein J. | pmid:21643844 |
| Metzger U et al. | The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19706516 |
| Schilmiller AL et al. | Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19487664 |
| Bohlmann J and Gershenzon J | Old substrates for new enzymes of terpenoid biosynthesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19553206 |
| Leonard E et al. | Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20643967 |
| Henry LK et al. | Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26216978 |
| Adam P et al. | Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12198182 |
| Benko AL et al. | Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10618371 |
| Kuzuyama T and Seto H | Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. | 2012 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:22450534 |
| Goto T et al. | Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. | 2010 | PPAR Res | pmid:20613991 |
| Odom AR | Five questions about non-mevalonate isoprenoid biosynthesis. | 2011 | PLoS Pathog. | pmid:22216001 |
| Davey MS et al. | Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. | 2011 | PLoS Pathog. | pmid:21589907 |
| Eberl M et al. | A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. | 2009 | PLoS Pathog. | pmid:19229322 |
| Perrin RM et al. | Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. | 2007 | PLoS Pathog. | pmid:17432932 |
| Brilli F et al. | Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction "time-of-flight" mass spectrometry (PTR-TOF). | 2011 | PLoS ONE | pmid:21637822 |
| Yang J et al. | Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. | 2012 | PLoS ONE | pmid:22558074 |
| Atsbaha Zebelo S et al. | Chrysolina herbacea modulates terpenoid biosynthesis of Mentha aquatica L. | 2011 | PLoS ONE | pmid:21408066 |
| Tsang A et al. | Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. | 2011 | PLoS ONE | pmid:21694781 |
| Chen X et al. | Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. | 2013 | PLoS ONE | pmid:24278153 |
| Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
| Trowbridge AM et al. | Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations. | 2012 | PLoS ONE | pmid:22384238 |
| Bonitz T et al. | Evolutionary relationships of microbial aromatic prenyltransferases. | 2011 | PLoS ONE | pmid:22140437 |
| Lu J et al. | Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules. | 2011 | PLoS ONE | pmid:21935360 |
| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Hao da C et al. | The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing. | 2011 | PLoS ONE | pmid:21731678 |
| Nickerson ML et al. | UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy. | 2010 | PLoS ONE | pmid:20505825 |
| Baumeister S et al. | Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. | 2011 | PLoS ONE | pmid:21573242 |
| Zhang J et al. | AtSOFL1 and AtSOFL2 act redundantly as positive modulators of the endogenous content of specific cytokinins in Arabidopsis. | 2009 | PLoS ONE | pmid:20011053 |
| Ghirardo A et al. | Biogenic volatile organic compound and respiratory CO2 emissions after 13C-labeling: online tracing of C translocation dynamics in poplar plants. | 2011 | PLoS ONE | pmid:21387007 |
| Rubio-Aliaga I et al. | Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. | 2009 | PLoS ONE | pmid:19562077 |
| Correia DV et al. | Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. | 2009 | PLoS ONE | pmid:19479075 |
| Velasco R et al. | A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. | 2007 | PLoS ONE | pmid:18094749 |
| Fatima T et al. | Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. | 2012 | PLoS ONE | pmid:22558083 |
| Tidten-Luksch N et al. | IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. | 2012 | PLoS ONE | pmid:22563402 |
| Banerjee A et al. | Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. | 2016 | PLoS ONE | pmid:27548482 |
| Fox DT et al. | Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. | 2014 | PLoS ONE | pmid:24751777 |
| Vinella D et al. | Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. | 2009 | PLoS Genet. | pmid:19478995 |
| Sabehi G et al. | New insights into metabolic properties of marine bacteria encoding proteorhodopsins. | 2005 | PLoS Biol. | pmid:16008504 |
| Nair SC and Striepen B | What do human parasites do with a chloroplast anyway? | 2011 | PLoS Biol. | pmid:21912515 |
| Yeh E and DeRisi JL | Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum. | 2011 | PLoS Biol. | pmid:21912516 |
| Okada K et al. | Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. | 2002 | Planta | pmid:12029484 |
| Zeidler J and Lichtenthaler HK | Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. | 2001 | Planta | pmid:11469599 |
| Wu S et al. | Engineering triterpene metabolism in tobacco. | 2012 | Planta | pmid:22729821 |
| Arimura G et al. | Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. | 2008 | Planta | pmid:17924138 |
| Suzuki N et al. | Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. | 2012 | Planta | pmid:22729820 |
| Clastre M et al. | Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. | 2011 | Plant Signal Behav | pmid:22080790 |
| Li Z et al. | Effect of temperature on postillumination isoprene emission in oak and poplar. | 2011 | Plant Physiol. | pmid:21177471 |
| Rasulov B et al. | Postillumination isoprene emission: in vivo measurements of dimethylallyldiphosphate pool size and isoprene synthase kinetics in aspen leaves. | 2009 | Plant Physiol. | pmid:19129417 |
| Zhao P et al. | Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. | 2003 | Plant Physiol. | pmid:14551337 |
| Nogués I et al. | Dimethylallyl diphosphate and geranyl diphosphate pools of plant species characterized by different isoprenoid emissions. | 2006 | Plant Physiol. | pmid:16461390 |
| Schnee C et al. | The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. | 2002 | Plant Physiol. | pmid:12481088 |
| Akashi T et al. | Molecular cloning and characterization of a cDNA for pterocarpan 4-dimethylallyltransferase catalyzing the key prenylation step in the biosynthesis of glyceollin, a soybean phytoalexin. | 2009 | Plant Physiol. | pmid:19091879 |
| Yang T et al. | A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway. | 2016 | Plant Physiol. | pmid:27356974 |
| George GM et al. | Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. | 2010 | Plant Physiol. | pmid:20605913 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Schilmiller AL et al. | Studies of a biochemical factory: tomato trichome deep expressed sequence tag sequencing and proteomics. | 2010 | Plant Physiol. | pmid:20431087 |
| Jassbi AR et al. | Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm. | 2008 | Plant Physiol. | pmid:17965175 |
| Loivamäki M et al. | Arabidopsis, a model to study biological functions of isoprene emission? | 2007 | Plant Physiol. | pmid:17468218 |
| Muñoz-Bertomeu J et al. | Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. | 2006 | Plant Physiol. | pmid:16980564 |
| Cervantes-Cervantes M et al. | Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. | 2006 | Plant Physiol. | pmid:16581875 |
| Mayrhofer S et al. | Diurnal and seasonal variation of isoprene biosynthesis-related genes in grey poplar leaves. | 2005 | Plant Physiol. | pmid:16126852 |
| Sharkey TD et al. | Evolution of the isoprene biosynthetic pathway in kudzu. | 2005 | Plant Physiol. | pmid:15653811 |
| Sasaki K et al. | Cloning and characterization of naringenin 8-prenyltransferase, a flavonoid-specific prenyltransferase of Sophora flavescens. | 2008 | Plant Physiol. | pmid:18218974 |
| Rosenstiel TN et al. | Differential accumulation of dimethylallyl diphosphate in leaves and needles of isoprene- and methylbutenol-emitting and nonemitting species. | 2002 | Plant Physiol. | pmid:12114581 |
| Wolfertz M et al. | Rapid regulation of the methylerythritol 4-phosphate pathway during isoprene synthesis. | 2004 | Plant Physiol. | pmid:15286290 |
| Page JE et al. | Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing. | 2004 | Plant Physiol. | pmid:15064370 |
| Lange BM et al. | Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. | 2001 | Plant Physiol. | pmid:11553758 |
| Ghirardo A et al. | Metabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene. | 2014 | Plant Physiol. | pmid:24590857 |
| Loreto F et al. | 13C labeling reveals chloroplastic and extrachloroplastic pools of dimethylallyl pyrophosphate and their contribution to isoprene formation. | 2004 | Plant Physiol. | pmid:15286296 |
| Manzano D et al. | Overexpression of farnesyl diphosphate synthase in Arabidopsis mitochondria triggers light-dependent lesion formation and alters cytokinin homeostasis. | 2006 | Plant Mol. Biol. | pmid:16786301 |
| Phillips MA et al. | Functional identification and differential expression of 1-deoxy-D-xylulose 5-phosphate synthase in induced terpenoid resin formation of Norway spruce (Picea abies). | 2007 | Plant Mol. Biol. | pmid:17687625 |
| Bleeker PM et al. | RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes. | 2011 | Plant Mol. Biol. | pmid:21818683 |
| Behnke K et al. | RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. | 2010 | Plant Mol. Biol. | pmid:20526857 |
| Schmidt A et al. | Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). | 2011 | Plant Mol. Biol. | pmid:22002747 |
| Delourme D et al. | Cloning of an Arabidopsis thaliana cDNA coding for farnesyl diphosphate synthase by functional complementation in yeast. | 1994 | Plant Mol. Biol. | pmid:7858223 |
| Angaman DM et al. | Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. | 2012 | Plant Methods | pmid:22243738 |
| Masferrer A et al. | Overexpression of Arabidopsis thaliana farnesyl diphosphate synthase (FPS1S) in transgenic Arabidopsis induces a cell death/senescence-like response and reduced cytokinin levels. | 2002 | Plant J. | pmid:12000449 |
| Behnke K et al. | Transgenic, non-isoprene emitting poplars don't like it hot. | 2007 | Plant J. | pmid:17587235 |
| Gonzales-Vigil E et al. | Evolution of TPS20-related terpene synthases influences chemical diversity in the glandular trichomes of the wild tomato relative Solanum habrochaites. | 2012 | Plant J. | pmid:22563774 |
| Kishi-Kaboshi M et al. | A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis. | 2010 | Plant J. | pmid:20525005 |
| Botella-PavÃa P et al. | Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. | 2004 | Plant J. | pmid:15447646 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Hirano K et al. | Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. | 2008 | Plant Cell Physiol. | pmid:18718932 |
| Wiberley AE et al. | Regulation of isoprene emission in Populus trichocarpa leaves subjected to changing growth temperature. | 2008 | Plant Cell Environ. | pmid:17996012 |
| Rasulov B et al. | Competition between isoprene emission and pigment synthesis during leaf development in aspen. | 2014 | Plant Cell Environ. | pmid:24033429 |
| Wiberley AE et al. | Regulation of isoprene emission from poplar leaves throughout a day. | 2009 | Plant Cell Environ. | pmid:19389050 |
| Phillips MA et al. | The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis. | 2008 | Plant Cell | pmid:18319397 |
| Guevara-GarcÃa A et al. | Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscriptional regulation of the methyl-D-erythritol 4-phosphate pathway. | 2005 | Plant Cell | pmid:15659625 |