Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

Cross Reference

Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dimethylallyl pyrophosphate?

Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dimethylallyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Dimethylallyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Dimethylallyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dimethylallyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Dimethylallyl pyrophosphate

Download all related citations
Per page 10 20 50 100 | Total 520
Authors Title Published Journal PubMed Link
pmid:
Miller B et al. A Synechococcus leopoliensis SAUG 1402-1 operon harboring the 1-deoxyxylulose 5-phosphate synthase gene and two additional open reading frames is functionally involved in the dimethylallyl diphosphate synthesis. 1999 FEBS Lett. pmid:10556522
Keller RK and Fliesler SJ Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. 1999 Biochem. Biophys. Res. Commun. pmid:10600541
Dieli F et al. Ligand-specific alphabeta and gammadelta T cell responses in childhood tuberculosis. 2000 J. Infect. Dis. pmid:10608778
Benko AL et al. Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10618371
Tachibana A et al. Novel prenyltransferase gene encoding farnesylgeranyl diphosphate synthase from a hyperthermophilic archaeon, Aeropyrum pernix. Molecularevolution with alteration in product specificity. 2000 Eur. J. Biochem. pmid:10632701
Schulbach MC et al. Identification of a short (C15) chain Z-isoprenyl diphosphate synthase and a homologous long (C50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis. 2000 J. Biol. Chem. pmid:10816587
Rodríguez-Concepción M et al. Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. 2000 FEBS Lett. pmid:10818234
Ershov Y et al. Isopentenyl diphosphate isomerase deficiency in Synechocystis sp. strain PCC6803. 2000 FEBS Lett. pmid:10818236
Leyes AE et al. Biosynthesis of isoprenoids in Escherichia coli: stereochemistry of the reaction catalyzed by farnesyl diphosphate synthase. 1999 Org. Lett. pmid:10825960
Hirooka K et al. Mechanism of product chain length determination for heptaprenyl diphosphate synthase from Bacillus stearothermophilus. 2000 Eur. J. Biochem. pmid:10880976
Hirooka K et al. The role of histidine-114 of Ssulfolobus acidocaldarius geranylgeranyl diphosphate synthase in chain-length determination. 2000 FEBS Lett. pmid:10984617
Cunningham FX et al. Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. 2000 J. Bacteriol. pmid:11004185
Miller B et al. Functional involvement of a deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. 2000 FEBS Lett. pmid:11007968
Zhang YW et al. Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. 2000 Biochemistry pmid:11027152
Campos N et al. Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. 2001 Biochem. J. pmid:11115399
Eisenreich W et al. Deoxyxylulose phosphate pathway to terpenoids. 2001 Trends Plant Sci. pmid:11173292
Altincicek B et al. GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. 2001 J. Bacteriol. pmid:11274098
Durbecq V et al. Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. 2001 EMBO J. pmid:11285217
Takei K et al. Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana. 2001 J. Biol. Chem. pmid:11313355
pmid:11327834
Fisher AJ et al. Nonradioactive assay for cellular dimethylallyl diphosphate. 2001 Anal. Biochem. pmid:11355861
Tholl D et al. Partial purification and characterization of the short-chain prenyltransferases, gernayl diphospate synthase and farnesyl diphosphate synthase, from Abies grandis (grand fir). 2001 Arch. Biochem. Biophys. pmid:11368347
Trapp SC and Croteau RB Genomic organization of plant terpene synthases and molecular evolutionary implications. 2001 Genetics pmid:11404343
pmid:11408165
Zeidler J and Lichtenthaler HK Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. 2001 Planta pmid:11469599
pmid:11479373
Vissa VD and Brennan PJ The genome of Mycobacterium leprae: a minimal mycobacterial gene set. 2001 Genome Biol. pmid:11532219
Lange BM et al. Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. 2001 Plant Physiol. pmid:11553758
Phan RM and Poulter CD Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. 2001 J. Org. Chem. pmid:11578224
pmid:11746827
Richard SB et al. Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. 2002 J. Biol. Chem. pmid:11786530
Takagi M et al. [Overlooked targets for the development of antibacterial and antimalarial drugs and herbicides: diverse biosynthetic systems for the isoprene units]. 2002 Tanpakushitsu Kakusan Koso pmid:11808197
pmid:11829504
Wanke M et al. Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. 2001 Acta Biochim. Pol. pmid:11833775
Masferrer A et al. Overexpression of Arabidopsis thaliana farnesyl diphosphate synthase (FPS1S) in transgenic Arabidopsis induces a cell death/senescence-like response and reduced cytokinin levels. 2002 Plant J. pmid:12000449
Hoeffler JF et al. Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. 2002 Biochem. J. pmid:12010124
Okada K et al. Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. 2002 Planta pmid:12029484
Little DB and Croteau RB Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases delta-selinene synthase and gamma-humulene synthase. 2002 Arch. Biochem. Biophys. pmid:12051690
pmid:12110296
Rosenstiel TN et al. Differential accumulation of dimethylallyl diphosphate in leaves and needles of isoprene- and methylbutenol-emitting and nonemitting species. 2002 Plant Physiol. pmid:12114581
Liang PH et al. Structure, mechanism and function of prenyltransferases. 2002 Eur. J. Biochem. pmid:12135472
Mahmoud SS and Croteau RB Strategies for transgenic manipulation of monoterpene biosynthesis in plants. 2002 Trends Plant Sci. pmid:12167332
pmid:12176066
Riebeling C et al. The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. 2002 Br. J. Cancer pmid:12177810
Ershov YV et al. Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. 2002 J. Bacteriol. pmid:12193620
Adam P et al. Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12198182
Kuzuyama T Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. 2002 Biosci. Biotechnol. Biochem. pmid:12353619
pmid:12355149
Kakimoto T [Cytokinin]. 2002 Tanpakushitsu Kakusan Koso pmid:12357630
Gossman W and Oldfield E Quantitative structure--activity relations for gammadelta T cell activation by phosphoantigens. 2002 J. Med. Chem. pmid:12383012
Hümbelin M et al. Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. 2002 Gene pmid:12384294
Schnee C et al. The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. 2002 Plant Physiol. pmid:12481088
Altincicek B et al. LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. 2002 FEBS Lett. pmid:12482608
Chen YH et al. Effects of prenyl pyrophosphates on the binding of PKCgamma with RACK1. 2003 J. Exp. Zoolog. Part A Comp. Exp. Biol. pmid:12506405
pmid:12529640
Wang H et al. Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells. 2003 J. Immunol. pmid:12646635
Turek-Etienne TC et al. Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase. 2003 Biochemistry pmid:12667062
Maurer-Stroh S et al. Protein prenyltransferases. 2003 Genome Biol. pmid:12702202
Wolff M et al. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. 2003 FEBS Lett. pmid:12706830
pmid:12721785
Hirohata S and Kikuchi H Behçet's disease. 2003 Arthritis Res. Ther. pmid:12723980
Hemmi H et al. An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase. 2003 Eur. J. Biochem. pmid:12752438
Hemmerlin A et al. Enzymes encoded by the farnesyl diphosphate synthase gene family in the Big Sagebrush Artemisia tridentata ssp. spiciformis. 2003 J. Biol. Chem. pmid:12782626
Bick JA and Lange BM Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane. 2003 Arch. Biochem. Biophys. pmid:12831836
Triolo G et al. Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. 2003 Arthritis Res. Ther. pmid:12932289
Carter OA et al. Monoterpene biosynthesis pathway construction in Escherichia coli. 2003 Phytochemistry pmid:12943759
pmid:14529427
Zhao P et al. Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures. 2003 Plant Physiol. pmid:14551337
Neundorf I et al. Evidence for the combined participation of a C10 and a C15 precursor in the biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics. 2003 Chembiochem pmid:14613112
pmid:14629038
Gray CR et al. Studies on the biosynthesis of asperparaline A: origin of the spirosuccinimde ring system. 2003 J. Am. Chem. Soc. pmid:14640629
Burke C et al. Heteromeric geranyl diphosphate synthase from mint: construction of a functional fusion protein and inhibition by bisphosphonate substrate analogs. 2004 Arch. Biochem. Biophys. pmid:14725857
Kasahara H et al. Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. 2004 J. Biol. Chem. pmid:14726522
Vitali A et al. Chalcone dimethylallyltransferase from Morus nigra cell cultures. Substrate specificity studies. 2004 FEBS Lett. pmid:14741337
Takagi M et al. Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase. 2004 Biosci. Biotechnol. Biochem. pmid:14745175
Thompson K and Rogers MJ Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. 2004 J. Bone Miner. Res. pmid:14969398
Brandt W et al. A proposed mechanism for the reductive ring opening of the cyclodiphosphate MEcPP, a crucial transformation in the new DXP/MEP pathway to isoprenoids based on modeling studies and feeding experiments. 2004 Chembiochem pmid:14997523
Yamashita S et al. Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae. 2004 Eur. J. Biochem. pmid:15009187
Dhiman RK et al. Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. 2004 J. Lipid Res. pmid:15060088
Page JE et al. Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing. 2004 Plant Physiol. pmid:15064370
Rosenstiel TN et al. Induction of poplar leaf nitrate reductase: a test of extrachloroplastic control of isoprene emission rate. 2004 Jan-Feb Plant Biol (Stuttg) pmid:15095130
Chau M and Croteau R Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. 2004 Arch. Biochem. Biophys. pmid:15178487
pmid:15197467
Laupitz R et al. Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. 2004 Eur. J. Biochem. pmid:15206931
Poliquin K et al. Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. 2004 J. Bacteriol. pmid:15231801
pmid:15279616
Wolfertz M et al. Rapid regulation of the methylerythritol 4-phosphate pathway during isoprene synthesis. 2004 Plant Physiol. pmid:15286290
Loreto F et al. 13C labeling reveals chloroplastic and extrachloroplastic pools of dimethylallyl pyrophosphate and their contribution to isoprene formation. 2004 Plant Physiol. pmid:15286296
pmid:15369345
Rohdich F et al. Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate. 2004 Bioorg. Chem. pmid:15381396
pmid:15388934
Botella-Pavía P et al. Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. 2004 Plant J. pmid:15447646
Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA. 2002 J. Insect Sci. pmid:15455051
pmid:15469281
pmid:15474569
Nagaki M et al. Substrate specificities of several prenyl chain elongating enzymes with respect to 4-methyl-4-pentenyl diphosphate. 2004 Biosci. Biotechnol. Biochem. pmid:15502351
Wille A et al. Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. 2004 Genome Biol. pmid:15535868
Raschke M et al. A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. 2004 Anal. Biochem. pmid:15556562
Mekkriengkrai D et al. Cloning and characterization of farnesyl diphosphate synthase from the rubber-producing mushroom Lactarius chrysorrheus. 2004 Biosci. Biotechnol. Biochem. pmid:15564677