| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sharma NK et al. | Type II isopentenyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues. | 2010 | Biochemistry | pmid:20560533 |
| Kloer DP et al. | Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. | 2006 | Biochemistry | pmid:17176041 |
| Qian Q et al. | Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase. | 2012 | Biochemistry | pmid:22935004 |
| Chen M and Poulter CD | Characterization of thermophilic archaeal isopentenyl phosphate kinases. | 2010 | Biochemistry | pmid:19928876 |
| Rothman SC et al. | Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. | 2007 | Biochemistry | pmid:17428035 |
| Koyama T et al. | Identification of significant residues in the substrate binding site of Bacillus stearothermophilus farnesyl diphosphate synthase. | 1996 | Biochemistry | pmid:8755734 |
| Zhang YW et al. | Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. | 2000 | Biochemistry | pmid:11027152 |
| Pan LL et al. | Origin of product selectivity in a prenyl transfer reaction from the same intermediate: exploration of multiple FtmPT1-catalyzed prenyl transfer pathways. | 2014 | Biochemistry | pmid:25188320 |
| Rohdich F et al. | Isoprenoid biosynthetic pathways as anti-infective drug targets. | 2005 | Biochem. Soc. Trans. | pmid:16042599 |
| Sillero MA et al. | Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. | 2009 | Biochem. Pharmacol. | pmid:19414000 |
| Campos N et al. | Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. | 2001 | Biochem. J. | pmid:11115399 |
| Banthorpe DV et al. | Biosynthesis of geraniol and nerol and beta-D-glucosides in Pelargonium graveolens and Rosa dilecta. | 1972 | Biochem. J. | pmid:4348258 |
| Rohmer M et al. | Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. | 1993 | Biochem. J. | pmid:8240251 |
| Hoeffler JF et al. | Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. | 2002 | Biochem. J. | pmid:12010124 |
| Fujiwara S et al. | Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system. | 2008 | Biochem. Biophys. Res. Commun. | pmid:17976371 |
| Koyama T et al. | Significance of Phe-220 and Gln-221 in the catalytic mechanism of farnesyl diphosphate synthase of Bacillus stearothermophilus. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7626083 |
| Deneris ES et al. | In vitro biosynthesis of isoprene from mevalonate utilizing a rat liver cytosolic fraction. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487307 |
| Keller RK and Fliesler SJ | Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10600541 |
| Glickman JF and Schmid A | Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. | 2007 | Assay Drug Dev Technol | pmid:17477829 |
| Accardo-Palumbo A et al. | Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity. | 2010 | Arthritis Res. Ther. | pmid:20525258 |
| Triolo G et al. | Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. | 2003 | Arthritis Res. Ther. | pmid:12932289 |
| Hirohata S and Kikuchi H | Behçet's disease. | 2003 | Arthritis Res. Ther. | pmid:12723980 |
| Zhang YL and Li ZX | Functional analysis and molecular docking identify two active short-chain prenyltransferases in the green peach aphid, Myzus persicae. | 2012 | Arch. Insect Biochem. Physiol. | pmid:22696503 |
| Tholl D et al. | Partial purification and characterization of the short-chain prenyltransferases, gernayl diphospate synthase and farnesyl diphosphate synthase, from Abies grandis (grand fir). | 2001 | Arch. Biochem. Biophys. | pmid:11368347 |
| Chau M and Croteau R | Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. | 2004 | Arch. Biochem. Biophys. | pmid:15178487 |
| Little DB and Croteau RB | Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases delta-selinene synthase and gamma-humulene synthase. | 2002 | Arch. Biochem. Biophys. | pmid:12051690 |
| Bick JA and Lange BM | Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane. | 2003 | Arch. Biochem. Biophys. | pmid:12831836 |
| Burke C et al. | Heteromeric geranyl diphosphate synthase from mint: construction of a functional fusion protein and inhibition by bisphosphonate substrate analogs. | 2004 | Arch. Biochem. Biophys. | pmid:14725857 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Morrone D et al. | Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19777230 |
| Das A et al. | An update on microbial carotenoid production: application of recent metabolic engineering tools. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17912511 |
| Withers ST and Keasling JD | Biosynthesis and engineering of isoprenoid small molecules. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115212 |
| Liu C et al. | Functional analysis of a prenyltransferase gene (paxD) in the paxilline biosynthetic gene cluster. | 2014 | Appl. Microbiol. Biotechnol. | pmid:23525886 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Cann AF and Liao JC | Pentanol isomer synthesis in engineered microorganisms. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19859707 |
| Scott E et al. | Biomass in the manufacture of industrial products--the use of proteins and amino acids. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17387469 |
| Ku B et al. | Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | 2005 | Appl. Environ. Microbiol. | pmid:16269684 |
| Song L | A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. | 2006 | Appl. Biochem. Biotechnol. | pmid:16484724 |
| Testa CA and Johnson LJ | A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. | 2012 | Antimicrob. Agents Chemother. | pmid:22777049 |
| Zhao L et al. | Methylerythritol phosphate pathway of isoprenoid biosynthesis. | 2013 | Annu. Rev. Biochem. | pmid:23746261 |
| Gräwert T et al. | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19569147 |
| Teufel R et al. | One-pot enzymatic synthesis of merochlorin A and B. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25115835 |
| Weise SE et al. | Measuring dimethylallyl diphosphate available for isoprene synthesis. | 2013 | Anal. Biochem. | pmid:23262281 |
| Zhou C et al. | Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. | 2013 | Anal. Biochem. | pmid:23747531 |
| Nagel R et al. | Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. | 2012 | Anal. Biochem. | pmid:22266300 |
| Dozier JK and Distefano MD | An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. | 2012 | Anal. Biochem. | pmid:22085443 |
| Raschke M et al. | A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. | 2004 | Anal. Biochem. | pmid:15556562 |
| Chung JA et al. | Purification of prenylated proteins by affinity chromatography on cyclodextrin-modified agarose. | 2009 | Anal. Biochem. | pmid:18834849 |
| Fisher AJ et al. | Nonradioactive assay for cellular dimethylallyl diphosphate. | 2001 | Anal. Biochem. | pmid:11355861 |
| Kalinowska-Tłuścik J et al. | A triclinic crystal form of Escherichia coli 4-diphosphocytidyl-2C-methyl-D-erythritol kinase and reassessment of the quaternary structure. | 2010 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:20208151 |