LipidPedia

Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

Cross Reference

Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

MeSH term	MeSH ID	Detail
Melanoma	D008545	69 associated lipids

MeSH term

Melanoma

Per page 10 20 50 100 | Total 520

Authors	Title	Published	Journal	PubMed Link
Sillero MA et al.	Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts.	2009	Biochem. Pharmacol.	pmid:19414000
Rohdich F et al.	Isoprenoid biosynthetic pathways as anti-infective drug targets.	2005	Biochem. Soc. Trans.	pmid:16042599
Sharma NK et al.	Type II isopentenyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues.	2010	Biochemistry	pmid:20560533
Xu W et al.	A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase.	2012	Biochemistry	pmid:22646150
Kloer DP et al.	Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba.	2006	Biochemistry	pmid:17176041
Qian Q et al.	Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase.	2012	Biochemistry	pmid:22935004
Turek-Etienne TC et al.	Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase.	2003	Biochemistry	pmid:12667062
Chen M and Poulter CD	Characterization of thermophilic archaeal isopentenyl phosphate kinases.	2010	Biochemistry	pmid:19928876
Rothman SC et al.	Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species.	2007	Biochemistry	pmid:17428035
Sagami H et al.	Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus.	1977	Biochemistry	pmid:911777
Thibodeaux CJ et al.	Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus.	2008	Biochemistry	pmid:18229948
Koyama T et al.	Identification of significant residues in the substrate binding site of Bacillus stearothermophilus farnesyl diphosphate synthase.	1996	Biochemistry	pmid:8755734
Kittleman W et al.	Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus.	2007	Biochemistry	pmid:17585782
Moore JA and Poulter CD	Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: a binding mechanism for recombinant enzyme.	1997	Biochemistry	pmid:9012675
Zhang YW et al.	Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination.	2000	Biochemistry	pmid:11027152
Pan LL et al.	Origin of product selectivity in a prenyl transfer reaction from the same intermediate: exploration of multiple FtmPT1-catalyzed prenyl transfer pathways.	2014	Biochemistry	pmid:25188320
Casey J and Threlfall DR	Formation of 3-hexaprenyl-4-hydroxybenzoate by matrix-free mitochondrial membrane-rich preparations of yeast.	1978	Biochim. Biophys. Acta	pmid:359053
Berthelot K et al.	Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis.	2012	Biochimie	pmid:22503704
Kiran U et al.	Structural and functional characterization of HMG-COA reductase from Artemisia annua.	2010	Bioinformation	pmid:21364776
Rohdich F et al.	Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate.	2004	Bioorg. Chem.	pmid:15381396

Dimethylallyl pyrophosphate

Cross Reference

Introduction

What diseases are associated with Dimethylallyl pyrophosphate?

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PubChem Associated disorders and diseases

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PubChem Biomolecular Interactions and Pathways

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Visualization in cellular structure

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What lipids are associated with Dimethylallyl pyrophosphate?

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What genes are associated with Dimethylallyl pyrophosphate?

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What common seen animal models are associated with Dimethylallyl pyrophosphate?

NCBI Entrez Crosslinks

All references with Dimethylallyl pyrophosphate

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