MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Brinkhaus FL and Rilling HC | Purification of geranylgeranyl diphosphate synthase from Phycomyces blakesleanus. | 1988 | Arch. Biochem. Biophys. | pmid:3190245 |
Bruenger E and Rilling HC | Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. | 1988 | Anal. Biochem. | pmid:3189812 |
Gotoh T et al. | Different roles of the diphosphate moieties of allylic and homoallylic diphosphates in prenyltransferase reaction. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3178843 |
Ito M et al. | Stereochemical analysis of prenyltransferase reactions leading to (Z)- and (E)-polyprenyl chains. | 1987 | Biochemistry | pmid:3117106 |
Reardon JE and Abeles RH | Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. | 1986 | Biochemistry | pmid:3022798 |
Davisson VJ et al. | Synthesis of allylic and homoallylic isoprenoid pyrophosphates. | 1985 | Meth. Enzymol. | pmid:2991702 |
Nave JF et al. | Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate. | 1985 | Biochem. J. | pmid:2986604 |
Lee CS and O'Sullivan WJ | Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase. | 1985 | Biochim. Biophys. Acta | pmid:2983770 |
Sagami H et al. | The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. | 1989 | Biochim. Biophys. Acta | pmid:2930770 |
pmid:29143298 |