MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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RodrÃguez-Concepción M et al. | Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. | 2000 | FEBS Lett. | pmid:10818234 |
Grove JE et al. | The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase. | 2000 | J. Bone Miner. Res. | pmid:10804029 |
Matthews PD and Wurtzel ET | Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase. | 2000 | Appl. Microbiol. Biotechnol. | pmid:10803894 |
Morita CT et al. | Recognition of nonpeptide prenyl pyrophosphate antigens by human gammadelta T cells. | 1999 | Microbes Infect. | pmid:10801228 |
Kuzuyama T et al. | Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues. | 2000 | J. Biol. Chem. | pmid:10787409 |
Oh SK et al. | Molecular cloning, expression, and functional analysis of a cis-prenyltransferase from Arabidopsis thaliana. Implications in rubber biosynthesis. | 2000 | J. Biol. Chem. | pmid:10764783 |
Cunningham FX and Gantt E | Identification of multi-gene families encoding isopentenyl diphosphate isomerase in plants by heterologous complementation in Escherichia coli. | 2000 | Plant Cell Physiol. | pmid:10750717 |
Charon L et al. | Deuterium-labelled isotopomers of 2-C-methyl-D-erythritol as tools for the elucidation of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. | 2000 | Biochem. J. | pmid:10698701 |
Cane DE | Perspectives: biosynthetic pathways. Biosynthesis meets bioinformatics. | 2000 | Science | pmid:10691559 |
Dairi T et al. | Cloning of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from terpenoid antibiotic-producing Streptomyces strains. | 2000 | Mol. Gen. Genet. | pmid:10660057 |