Richard SB et al. |
Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. |
2002 |
J. Biol. Chem. |
pmid:11786530
|
Pan JJ et al. |
Insight into the activation mechanism of Escherichia coli octaprenyl pyrophosphate synthase derived from pre-steady-state kinetic analysis. |
2002 |
Biochim. Biophys. Acta |
pmid:11825609
|
|
|
|
|
pmid:11829504
|
Wanke M et al. |
Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. |
2001 |
Acta Biochim. Pol. |
pmid:11833775
|
Hedl M et al. |
Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis. |
2002 |
J. Bacteriol. |
pmid:11914342
|
|
|
|
|
pmid:11976546
|
Gougeon ML et al. |
Innate T cell immunity to HIV-infection. Immunotherapy with phosphocarbohydrates, a novel strategy of immune intervention? |
2002 |
Vaccine |
pmid:11983250
|
Glatzel A et al. |
Patterns of chemokine receptor expression on peripheral blood gamma delta T lymphocytes: strong expression of CCR5 is a selective feature of V delta 2/V gamma 9 gamma delta T cells. |
2002 |
J. Immunol. |
pmid:11994442
|
Hoeffler JF et al. |
Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. |
2002 |
Biochem. J. |
pmid:12010124
|
Okada K et al. |
Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. |
2002 |
Planta |
pmid:12029484
|
Lafitte D et al. |
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. |
2002 |
Biochemistry |
pmid:12044152
|
Espinosa E et al. |
Synaptic transfer by human gamma delta T cells stimulated with soluble or cellular antigens. |
2002 |
J. Immunol. |
pmid:12055250
|
|
|
|
|
pmid:12073030
|
Amslinger S et al. |
Biosynthesis of terpenes. Preparation of (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate, an intermediate of the deoxyxylulose phosphate pathway. |
2002 |
J. Org. Chem. |
pmid:12076162
|
Sutherlin A et al. |
Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis. |
2002 |
J. Bacteriol. |
pmid:12107122
|
|
|
|
|
pmid:12110296
|
Liang PH et al. |
Structure, mechanism and function of prenyltransferases. |
2002 |
Eur. J. Biochem. |
pmid:12135472
|
Brodelius M et al. |
Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. |
2002 |
Eur. J. Biochem. |
pmid:12135497
|
Mahmoud SS and Croteau RB |
Strategies for transgenic manipulation of monoterpene biosynthesis in plants. |
2002 |
Trends Plant Sci. |
pmid:12167332
|
|
|
|
|
pmid:12176066
|
Riebeling C et al. |
The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. |
2002 |
Br. J. Cancer |
pmid:12177810
|
Ershov YV et al. |
Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. |
2002 |
J. Bacteriol. |
pmid:12193620
|
Adam P et al. |
Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12198182
|
Kuzuyama T |
Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12353619
|
Dagna L et al. |
Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. |
2002 |
Eur. J. Immunol. |
pmid:12355447
|
Brüggemann N and Schnitzler JP |
Relationship of isopentenyl diphosphate (IDP) isomerase activity to isoprene emission of oak leaves. |
2002 |
Tree Physiol. |
pmid:12359528
|
|
|
|
|
pmid:12374295
|
Hümbelin M et al. |
Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. |
2002 |
Gene |
pmid:12384294
|
Cipriani B et al. |
Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens. |
2002 |
J. Immunol. |
pmid:12421956
|
Hirooka K et al. |
Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. |
2003 |
Biochem. J. |
pmid:12437513
|
Nagata N et al. |
Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. |
2002 |
Planta |
pmid:12447549
|
|
|
|
|
pmid:12479413
|
Altincicek B et al. |
LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. |
2002 |
FEBS Lett. |
pmid:12482608
|
Chen AP et al. |
Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase. |
2002 |
J. Am. Chem. Soc. |
pmid:12487597
|
|
|
|
|
pmid:12499403
|
Flores-Sánchez IJ et al. |
Biosynthesis of sterols and triterpenes in cell suspension cultures of Uncaria tomentosa. |
2002 |
Plant Cell Physiol. |
pmid:12514247
|
Miyazawa Y et al. |
Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. |
2002 |
Plant Cell Physiol. |
pmid:12514251
|
|
|
|
|
pmid:12531482
|
Palazón J et al. |
Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. |
2003 |
J. Biotechnol. |
pmid:12568744
|
Wang YD et al. |
Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. |
2003 |
Biotechnol. Appl. Biochem. |
pmid:12578550
|
Biswas P et al. |
Double-edged effect of Vgamma9/Vdelta2 T lymphocytes on viral expression in an in vitro model of HIV-1/mycobacteria co-infection. |
2003 |
Eur. J. Immunol. |
pmid:12594854
|
|
|
|
|
pmid:12630859
|
Wang H et al. |
Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells. |
2003 |
J. Immunol. |
pmid:12646635
|
Reichenberg A et al. |
Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12657258
|
Gallagher CE et al. |
Surrogate biochemistry: use of Escherichia coli to identify plant cDNAs that impact metabolic engineering of carotenoid accumulation. |
2003 |
Appl. Microbiol. Biotechnol. |
pmid:12664151
|
|
|
|
|
pmid:12680756
|
Bieback K et al. |
Expansion of human gamma/delta T cells in vitro is differentially regulated by the measles virus glycoproteins. |
2003 |
J. Gen. Virol. |
pmid:12692283
|
Wolff M et al. |
Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. |
2003 |
FEBS Lett. |
pmid:12706830
|
Kuzuyama T and Seto H |
Diversity of the biosynthesis of the isoprene units. |
2003 |
Nat Prod Rep |
pmid:12735695
|
Hemmerlin A et al. |
Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. |
2003 |
J. Biol. Chem. |
pmid:12736259
|
Laule O et al. |
Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12748386
|
Kawasaki T et al. |
Interconversion of the product specificity of type I eubacterial farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase through one amino acid substitution. |
2003 |
J. Biochem. |
pmid:12761202
|
Hemmerlin A et al. |
Enzymes encoded by the farnesyl diphosphate synthase gene family in the Big Sagebrush Artemisia tridentata ssp. spiciformis. |
2003 |
J. Biol. Chem. |
pmid:12782626
|
Hong SB et al. |
Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. |
2003 May-Jun |
Biotechnol. Prog. |
pmid:12790690
|
Bick JA and Lange BM |
Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane. |
2003 |
Arch. Biochem. Biophys. |
pmid:12831836
|
Souret FF et al. |
Scale-up of Artemisia annua L. hairy root cultures produces complex patterns of terpenoid gene expression. |
2003 |
Biotechnol. Bioeng. |
pmid:12889030
|
Triolo G et al. |
Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleukin-12 receptor beta1 expression in active disease. |
2003 |
Arthritis Res. Ther. |
pmid:12932289
|
Carter OA et al. |
Monoterpene biosynthesis pathway construction in Escherichia coli. |
2003 |
Phytochemistry |
pmid:12943759
|
BLOCH K et al. |
Mevalonic acid pyrophosphate and isopentenylpyrophosphate. |
1959 |
J. Biol. Chem. |
pmid:13801508
|
Tait RM |
Development of a radiometric spot-wash assay for squalene synthase. |
1992 |
Anal. Biochem. |
pmid:1416027
|
Mau CJ et al. |
Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. |
2003 |
Eur. J. Biochem. |
pmid:14511375
|
Zenitani S et al. |
Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. |
2003 |
J. Antibiot. |
pmid:14513904
|
Neundorf I et al. |
Evidence for the combined participation of a C10 and a C15 precursor in the biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics. |
2003 |
Chembiochem |
pmid:14613112
|
Guo RT et al. |
Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination. |
2004 |
J. Biol. Chem. |
pmid:14617622
|
|
|
|
|
pmid:14629038
|
Bajguz A and Asami T |
Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris. |
2004 |
Planta |
pmid:14655015
|
Chang SY et al. |
Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase. |
2003 |
Biochemistry |
pmid:14661956
|
Hogenboom S et al. |
Cholesterol biosynthesis is not defective in peroxisome biogenesis defective fibroblasts. |
2003 |
Mol. Genet. Metab. |
pmid:14680974
|
|
|
|
|
pmid:14696183
|
Workalemahu G et al. |
Expression and synthesis of fibroblast growth factor-9 in human gammadelta T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-beta1/IL-15. |
2004 |
J. Leukoc. Biol. |
pmid:14704367
|
|
|
|
|
pmid:14711397
|
|
|
|
|
pmid:14718497
|
Burke C et al. |
Heteromeric geranyl diphosphate synthase from mint: construction of a functional fusion protein and inhibition by bisphosphonate substrate analogs. |
2004 |
Arch. Biochem. Biophys. |
pmid:14725857
|
Kasahara H et al. |
Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. |
2004 |
J. Biol. Chem. |
pmid:14726522
|
Takagi M et al. |
Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase. |
2004 |
Biosci. Biotechnol. Biochem. |
pmid:14745175
|
Scholte AA et al. |
Synthesis and biological activity of isopentenyl diphosphate analogues. |
2004 |
Bioorg. Med. Chem. |
pmid:14759736
|
Kawasaki T et al. |
A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. |
2003 |
J. Antibiot. |
pmid:14763562
|
Hedl M and Rodwell VW |
Enterococcus faecalis mevalonate kinase. |
2004 |
Protein Sci. |
pmid:14767074
|
Kharel Y et al. |
Significance of highly conserved aromatic residues in Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase. |
2003 |
J. Biochem. |
pmid:14769870
|
Thompson K and Rogers MJ |
Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. |
2004 |
J. Bone Miner. Res. |
pmid:14969398
|
Fuse M et al. |
Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14985133
|
Fraser PD and Bramley PM |
The biosynthesis and nutritional uses of carotenoids. |
2004 |
Prog. Lipid Res. |
pmid:15003396
|
Yamashita S et al. |
Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae. |
2004 |
Eur. J. Biochem. |
pmid:15009187
|
Chojnacki T |
Preparation of tritium-labeled 3-methyl-3-buten-1[3H]-yl diphosphate (3H-isopentenyl diphosphate). |
2004 |
Meth. Enzymol. |
pmid:15038965
|
Chang SY et al. |
Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies. |
2004 |
Protein Sci. |
pmid:15044730
|
Burlat V et al. |
Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites. |
2004 |
Plant J. |
pmid:15053766
|
Dhiman RK et al. |
Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. |
2004 |
J. Lipid Res. |
pmid:15060088
|
Ralph SA et al. |
Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. |
2004 |
Nat. Rev. Microbiol. |
pmid:15083156
|
|
|
|
|
pmid:15110773
|
Kalyan S and Chow AW |
Human peripheral gammadelta T cells potentiate the early proinflammatory cytokine response to staphylococcal toxic shock syndrome toxin-1. |
2004 |
J. Infect. Dis. |
pmid:15122526
|
Glazko GV and Mushegian AR |
Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns. |
2004 |
Genome Biol. |
pmid:15128446
|
Chau M and Croteau R |
Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. |
2004 |
Arch. Biochem. Biophys. |
pmid:15178487
|
|
|
|
|
pmid:15196010
|
Kunzmann V et al. |
Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons. |
2004 |
Immunology |
pmid:15196204
|
|
|
|
|
pmid:15197467
|
Laupitz R et al. |
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. |
2004 |
Eur. J. Biochem. |
pmid:15206931
|
Poliquin K et al. |
Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. |
2004 |
J. Bacteriol. |
pmid:15231801
|
Verjans GM et al. |
Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes. |
2004 |
J. Infect. Dis. |
pmid:15243921
|
|
|
|
|
pmid:15257386
|
|
|
|
|
pmid:15279616
|