| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Richard SB et al. | Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. | 2002 | J. Biol. Chem. | pmid:11786530 |
| Pan JJ et al. | Insight into the activation mechanism of Escherichia coli octaprenyl pyrophosphate synthase derived from pre-steady-state kinetic analysis. | 2002 | Biochim. Biophys. Acta | pmid:11825609 |
| pmid:11829504 | ||||
| Wanke M et al. | Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. | 2001 | Acta Biochim. Pol. | pmid:11833775 |
| Hedl M et al. | Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis. | 2002 | J. Bacteriol. | pmid:11914342 |
| pmid:11976546 | ||||
| Gougeon ML et al. | Innate T cell immunity to HIV-infection. Immunotherapy with phosphocarbohydrates, a novel strategy of immune intervention? | 2002 | Vaccine | pmid:11983250 |
| Glatzel A et al. | Patterns of chemokine receptor expression on peripheral blood gamma delta T lymphocytes: strong expression of CCR5 is a selective feature of V delta 2/V gamma 9 gamma delta T cells. | 2002 | J. Immunol. | pmid:11994442 |
| Hoeffler JF et al. | Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. | 2002 | Biochem. J. | pmid:12010124 |
| Okada K et al. | Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. | 2002 | Planta | pmid:12029484 |
| Lafitte D et al. | DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. | 2002 | Biochemistry | pmid:12044152 |
| Espinosa E et al. | Synaptic transfer by human gamma delta T cells stimulated with soluble or cellular antigens. | 2002 | J. Immunol. | pmid:12055250 |
| pmid:12073030 | ||||
| Amslinger S et al. | Biosynthesis of terpenes. Preparation of (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate, an intermediate of the deoxyxylulose phosphate pathway. | 2002 | J. Org. Chem. | pmid:12076162 |
| Sutherlin A et al. | Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis. | 2002 | J. Bacteriol. | pmid:12107122 |
| pmid:12110296 | ||||
| Liang PH et al. | Structure, mechanism and function of prenyltransferases. | 2002 | Eur. J. Biochem. | pmid:12135472 |
| Brodelius M et al. | Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. | 2002 | Eur. J. Biochem. | pmid:12135497 |
| Mahmoud SS and Croteau RB | Strategies for transgenic manipulation of monoterpene biosynthesis in plants. | 2002 | Trends Plant Sci. | pmid:12167332 |
| pmid:12176066 | ||||
| Riebeling C et al. | The bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro. | 2002 | Br. J. Cancer | pmid:12177810 |
| Ershov YV et al. | Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. | 2002 | J. Bacteriol. | pmid:12193620 |
| Adam P et al. | Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12198182 |
| Kuzuyama T | Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12353619 |
| Dagna L et al. | Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. | 2002 | Eur. J. Immunol. | pmid:12355447 |
| Brüggemann N and Schnitzler JP | Relationship of isopentenyl diphosphate (IDP) isomerase activity to isoprene emission of oak leaves. | 2002 | Tree Physiol. | pmid:12359528 |
| pmid:12374295 | ||||
| Hümbelin M et al. | Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. | 2002 | Gene | pmid:12384294 |
| Cipriani B et al. | Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens. | 2002 | J. Immunol. | pmid:12421956 |
| Hirooka K et al. | Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. | 2003 | Biochem. J. | pmid:12437513 |
| Nagata N et al. | Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. | 2002 | Planta | pmid:12447549 |
| pmid:12479413 | ||||
| Altincicek B et al. | LytB protein catalyzes the terminal step of the 2-C-methyl-D-erythritol-4-phosphate pathway of isoprenoid biosynthesis. | 2002 | FEBS Lett. | pmid:12482608 |
| Chen AP et al. | Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase. | 2002 | J. Am. Chem. Soc. | pmid:12487597 |
| pmid:12499403 | ||||
| Flores-Sánchez IJ et al. | Biosynthesis of sterols and triterpenes in cell suspension cultures of Uncaria tomentosa. | 2002 | Plant Cell Physiol. | pmid:12514247 |
| Miyazawa Y et al. | Amyloplast formation in cultured tobacco BY-2 cells requires a high cytokinin content. | 2002 | Plant Cell Physiol. | pmid:12514251 |
| pmid:12531482 | ||||
| Palazón J et al. | Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. | 2003 | J. Biotechnol. | pmid:12568744 |
| Wang YD et al. | Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. | 2003 | Biotechnol. Appl. Biochem. | pmid:12578550 |
| Biswas P et al. | Double-edged effect of Vgamma9/Vdelta2 T lymphocytes on viral expression in an in vitro model of HIV-1/mycobacteria co-infection. | 2003 | Eur. J. Immunol. | pmid:12594854 |
| pmid:12630859 | ||||
| Wang H et al. | Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells. | 2003 | J. Immunol. | pmid:12646635 |
| Reichenberg A et al. | Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12657258 |
| Gallagher CE et al. | Surrogate biochemistry: use of Escherichia coli to identify plant cDNAs that impact metabolic engineering of carotenoid accumulation. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12664151 |
| pmid:12680756 | ||||
| Bieback K et al. | Expansion of human gamma/delta T cells in vitro is differentially regulated by the measles virus glycoproteins. | 2003 | J. Gen. Virol. | pmid:12692283 |
| Wolff M et al. | Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. | 2003 | FEBS Lett. | pmid:12706830 |
| Kuzuyama T and Seto H | Diversity of the biosynthesis of the isoprene units. | 2003 | Nat Prod Rep | pmid:12735695 |
| Hemmerlin A et al. | Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. | 2003 | J. Biol. Chem. | pmid:12736259 |