Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Mi J et al. Age-related subproteomic analysis of mouse liver and kidney peroxisomes. 2007 Proteome Sci pmid:18042274
Huang CH et al. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. 2010 Proteins pmid:19876942
Doun SS et al. Enterococcus faecalis phosphomevalonate kinase. 2005 Protein Sci. pmid:15802646
Chang SY et al. Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies. 2004 Protein Sci. pmid:15044730
Hedl M and Rodwell VW Enterococcus faecalis mevalonate kinase. 2004 Protein Sci. pmid:14767074
Fraser PD and Bramley PM The biosynthesis and nutritional uses of carotenoids. 2004 Prog. Lipid Res. pmid:15003396
Rohmer M Isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs? 1998 Prog Drug Res pmid:9670778
Bohlmann J and Gershenzon J Old substrates for new enzymes of terpenoid biosynthesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19553206
Leonard E et al. Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20643967
Dudareva N et al. The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15630092