MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sagami H et al. | Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate. | 1993 | J. Biochem. | pmid:8407863 |
Sagami H et al. | Biosynthesis of prenyl diphosphates by cell-free extracts from mammalian tissues. | 1993 | J. Biochem. | pmid:8407862 |
Horbach S et al. | Isoprenoid biosynthesis in bacteria: two different pathways? | 1993 | FEMS Microbiol. Lett. | pmid:8405922 |
Islam M et al. | Dissociation of prelycopersene pyrophosphate synthetase from phytoene synthetase complex of tomato fruit plastids. | 1977 | J. Biol. Chem. | pmid:838727 |
Nishino T and Rudney H | Effects of detergents on the properties of 4-hydroxybenzoate. Polyprenyl transferase and the specificity of the polyprenyl pyrophosphate synthetic system in mitochondria. | 1977 | Biochemistry | pmid:836803 |
Sahm H et al. | Biochemistry and physiology of hopanoids in bacteria. | 1993 | Adv. Microb. Physiol. | pmid:8310881 |
Rohmer M et al. | Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. | 1993 | Biochem. J. | pmid:8240251 |
Runquist M et al. | Isoprenoid biosynthesis in rat liver mitochondria. Studies on farnesyl pyrophosphate synthase and trans-prenyltransferase. | 1994 | J. Biol. Chem. | pmid:8119922 |
Giron MD et al. | Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 1993 | Arch. Biochem. Biophys. | pmid:8097083 |
Christensen DJ and Poulter CD | Enzymatic synthesis of isotopically labeled isoprenoid diphosphates. | 1994 | Bioorg. Med. Chem. | pmid:7858969 |