Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

Download all related citations
Per page 10 20 50 100 | Total 1004
Authors Title Published Journal PubMed Link
Hunter WN Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. 2011 Curr Top Med Chem pmid:21619509
Elmore ZC et al. Sumo-dependent substrate targeting of the SUMO protease Ulp1. 2011 BMC Biol. pmid:22034919
Rogers TL and Holen I Tumour macrophages as potential targets of bisphosphonates. 2011 J Transl Med pmid:22005011
Li Z et al. Effect of temperature on postillumination isoprene emission in oak and poplar. 2011 Plant Physiol. pmid:21177471
Zheng Q et al. Diverse arrangement of photosynthetic gene clusters in aerobic anoxygenic phototrophic bacteria. 2011 PLoS ONE pmid:21949847
Kondo M et al. Expansion of human peripheral blood γδ T cells using zoledronate. 2011 J Vis Exp pmid:21931292
Kaneko Y et al. Stage-specific regulation of juvenile hormone biosynthesis by ecdysteroid in Bombyx mori. 2011 Mol. Cell. Endocrinol. pmid:21256183
Sasaki H et al. Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy. 2011 Mol Brain pmid:21658278
Plattner BL and Hostetter JM Comparative gamma delta T cell immunology: a focus on mycobacterial disease in cattle. 2011 Vet Med Int pmid:21647391
Almeida J et al. Genetic dissection of vitamin E biosynthesis in tomato. 2011 J. Exp. Bot. pmid:21527625
Bartoszewska M et al. The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. 2011 Biotechnol. Lett. pmid:21660569
Hoshino T et al. Crystallization and preliminary X-ray analysis of isopentenyl diphosphate isomerase from Methanocaldococcus jannaschii. 2011 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:21206036
Luo H et al. Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. 2011 BMC Genomics pmid:22369100
Silverman SL et al. Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid. 2011 Osteoporos Int pmid:21116816
Ohno K et al. Computational insights into binding of bisphosphates to farnesyl pyrophosphate synthase. 2011 Curr. Med. Chem. pmid:21110804
Thabet I et al. The subcellular localization of periwinkle farnesyl diphosphate synthase provides insight into the role of peroxisome in isoprenoid biosynthesis. 2011 J. Plant Physiol. pmid:21872968
Al-Bazi MM et al. Reduced coenzyme Q(10) in female smokers and its association with lipid profile in a young healthy adult population. 2011 Arch Med Sci pmid:22328876
Wang H et al. Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. 2011 J. Immunol. pmid:22013129
Heaps NA and Poulter CD Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism. 2011 J. Am. Chem. Soc. pmid:22047048
Cordero BF et al. Enhancement of carotenoids biosynthesis in Chlamydomonas reinhardtii by nuclear transformation using a phytoene synthase gene isolated from Chlorella zofingiensis. 2011 Appl. Microbiol. Biotechnol. pmid:21519934
Sawai S and Saito K Triterpenoid biosynthesis and engineering in plants. 2011 Front Plant Sci pmid:22639586
Artz JD et al. Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. 2011 J. Biol. Chem. pmid:21084289
Miziorko HM Enzymes of the mevalonate pathway of isoprenoid biosynthesis. 2011 Arch. Biochem. Biophys. pmid:20932952
Benzaïd I et al. High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo. 2011 Cancer Res. pmid:21646473
Berkun Y et al. GammadeltaT cells in juvenile idiopathic arthritis: higher percentages of synovial Vdelta1+ and Vgamma9+ T cell subsets are associated with milder disease. 2011 J. Rheumatol. pmid:21406498
Björkelid C et al. Structural and functional studies of mycobacterial IspD enzymes. 2011 Acta Crystallogr. D Biol. Crystallogr. pmid:21543842
Peralta-Yahya PP et al. Identification and microbial production of a terpene-based advanced biofuel. 2011 Nat Commun pmid:21952217
Misawa N Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. 2011 Mar Drugs pmid:21673887
Wu L et al. Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil. 2011 PLoS ONE pmid:21655235
Umeda T et al. Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum. 2011 Sci Rep pmid:22355528
Wen W and Yu R Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. 2011 Pharmacogn Rev pmid:22279377
Xiao Y et al. Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues. 2011 Org. Lett. pmid:21981393
Bang S et al. Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. 2011 Pain pmid:21353389
Clastre M et al. Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. 2011 Plant Signal Behav pmid:22080790
Qin G et al. Type 1 responses of human Vγ9Vδ2 T cells to influenza A viruses. 2011 J. Virol. pmid:21752902
Castella B et al. Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. 2011 J. Immunol. pmid:21753152
Davey MS et al. Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. 2011 PLoS Pathog. pmid:21589907
Okada K The biosynthesis of isoprenoids and the mechanisms regulating it in plants. 2011 Biosci. Biotechnol. Biochem. pmid:21737944
Baumeister S et al. Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. 2011 PLoS ONE pmid:21573242
Nair SC and Striepen B What do human parasites do with a chloroplast anyway? 2011 PLoS Biol. pmid:21912515
Yeh E and DeRisi JL Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum. 2011 PLoS Biol. pmid:21912516
Schmidt A et al. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). 2011 Plant Mol. Biol. pmid:22002747
Meier S et al. A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. 2011 BMC Syst Biol pmid:21595952
Martinez-Moya P et al. Proteomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous. 2011 BMC Microbiol. pmid:21669001
Sui C et al. Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins. 2011 BMC Genomics pmid:22047182
Lemuth K et al. Engineering of a plasmid-free Escherichia coli strain for improved in vivo biosynthesis of astaxanthin. 2011 Microb. Cell Fact. pmid:21521516
Harrison KD et al. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. 2011 EMBO J. pmid:21572394
Zhou K et al. Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCR. 2011 BMC Mol. Biol. pmid:21513543
Larsen L et al. Expression and localization of microRNAs in perinatal rat pancreas: role of miR-21 in regulation of cholesterol metabolism. 2011 PLoS ONE pmid:22022489
Barta ML et al. Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. 2011 J. Biol. Chem. pmid:21561869