|MeSH term||MeSH ID||Detail|
|Melanoma||D008545||69 associated lipids|
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
|Disease||Cross reference||Weighted score||Related literature|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
|Pathway name||Related literatures|
Associated locations are in red color. Not associated locations are in black.
|Function||Cross reference||Weighted score||Related literatures|
There are no associated biomedical information in the current reference collection.
|Chou HH and Keasling JD||Programming adaptive control to evolve increased metabolite production.||2013||Nat Commun||pmid:24131951|
|Gogoi D and Chiplunkar SV||Targeting gamma delta T cells for cancer immunotherapy: bench to bedside.||2013||Indian J. Med. Res.||pmid:24434328|
|Arens J et al.||Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family.||2013||Chem. Commun. (Camb.)||pmid:23295536|
|Ueno A et al.||Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis.||2013||Parasitol. Int.||pmid:23276703|
|Zhou C et al.||Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase.||2013||Anal. Biochem.||pmid:23747531|
|Tong H et al.||Quantitative determination of isopentenyl diphosphate in cultured mammalian cells.||2013||Anal. Biochem.||pmid:23000003|
|Leblond JD et al.||Sterol composition and biosynthetic genes of the recently discovered photosynthetic alveolate, Chromera velia (chromerida), a close relative of apicomplexans.||2012 May-Jun||J. Eukaryot. Microbiol.||pmid:22313428|
|Mabanglo MF et al.||The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.||2012||Biochemistry||pmid:22148590|
|Kumar M et al.||Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases.||2012||Exp Diabetes Res||pmid:22611376|
|Jonnalagadda V et al.||Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction.||2012||J. Am. Chem. Soc.||pmid:22471428|