MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Liu T and Khosla C | Chemistry. A balancing act for Taxol precursor pathways in E. coli. | 2010 | Science | pmid:20929799 |
Christianson DW | Chemistry. Roots of biosynthetic diversity. | 2007 | Science | pmid:17412944 |
Fischbach MA and Walsh CT | Biochemistry. Directing biosynthesis. | 2006 | Science | pmid:17068249 |
Ridley RG | Planting the seeds of new antimalarial drugs. | 1999 | Science | pmid:10498534 |
Jomaa H et al. | Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. | 1999 | Science | pmid:10477522 |
Zhao Y et al. | cDNA cloning, chromosome mapping and expression characterization of human geranylgeranyl pyrophosphate synthase. | 2000 | Sci. China, C, Life Sci. | pmid:18726356 |
Tardoski S et al. | Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer. | 2015 | Sci Rep | pmid:26578234 |
Umeda T et al. | Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum. | 2011 | Sci Rep | pmid:22355528 |
Kulaber A et al. | Pro-inflammatory cellular immune response in Behçet's disease. | 2007 | Rheumatol. Int. | pmid:17549482 |
Morita CT et al. | Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. | 1996 | Res. Immunol. | pmid:8876064 |