| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
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|---|---|---|---|---|
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| Tong H et al. | Quantitative determination of isopentenyl diphosphate in cultured mammalian cells. | 2013 | Anal. Biochem. | pmid:23000003 |
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| Lin YS et al. | Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells. | 2012 | J. Med. Chem. | pmid:22390415 |
| Park J et al. | Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. | 2012 | BMC Struct. Biol. | pmid:23234314 |
| Soriano-Sarabia N et al. | Primary MHC-class II(+) cells are necessary to promote resting Vδ2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate. | 2012 | J. Immunol. | pmid:23105138 |
| Yang J et al. | Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. | 2012 | PLoS ONE | pmid:22558074 |
| Span I et al. | Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. | 2012 | J. Mol. Biol. | pmid:22137895 |
| Testa CA and Johnson LJ | A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. | 2012 | Antimicrob. Agents Chemother. | pmid:22777049 |
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| Mohanta TK et al. | Ginkgo biloba responds to herbivory by activating early signaling and direct defenses. | 2012 | PLoS ONE | pmid:22448229 |
| Kuzuyama T and Seto H | Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. | 2012 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:22450534 |
| Caballero MC et al. | Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. | 2012 | Mol. Biochem. Parasitol. | pmid:22057350 |
| Wan L et al. | De novo transcriptomic analysis of an oleaginous microalga: pathway description and gene discovery for production of next-generation biofuels. | 2012 | PLoS ONE | pmid:22536352 |
| Mabanglo MF et al. | Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity. | 2012 | ACS Chem. Biol. | pmid:22533411 |
| Lei A et al. | Expression of fatty acid synthesis genes and fatty acid accumulation in haematococcus pluvialis under different stressors. | 2012 | Biotechnol Biofuels | pmid:22448811 |