| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schilmiller AL et al. | Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19487664 |
| Bohlmann J and Gershenzon J | Old substrates for new enzymes of terpenoid biosynthesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19553206 |
| Gräwert T et al. | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19569147 |
| Chung BK and Lee DY | Flux-sum analysis: a metabolite-centric approach for understanding the metabolic network. | 2009 | BMC Syst Biol | pmid:20021680 |
| Li X et al. | Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus. | 2009 | Int J Microbiol | pmid:20016671 |
| Cui Y et al. | Human gammadelta T cell recognition of lipid A is predominately presented by CD1b or CD1c on dendritic cells. | 2009 | Biol. Direct | pmid:19948070 |
| Gilg AB et al. | Unique animal prenyltransferase with monoterpene synthase activity. | 2009 | Naturwissenschaften | pmid:19277597 |
| Kumar S et al. | Comparative analysis of the complete sequence of the plastid genome of Parthenium argentatum and identification of DNA barcodes to differentiate Parthenium species and lines. | 2009 | BMC Plant Biol. | pmid:19917140 |
| Nymark M et al. | An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. | 2009 | PLoS ONE | pmid:19888450 |
| Simonsen HT et al. | Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates. | 2009 | Perspect Medicin Chem | pmid:19812738 |
| King FW et al. | Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. | 2009 | PLoS ONE | pmid:19789631 |
| Orlova I et al. | The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. | 2009 | Plant Cell | pmid:20028839 |
| Gunawardana D et al. | A comprehensive bioinformatics analysis of the Nudix superfamily in Arabidopsis thaliana. | 2009 | Comp. Funct. Genomics | pmid:19590748 |
| Chaudhuri RR et al. | Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH). | 2009 | BMC Genomics | pmid:19570206 |
| Paniagua-Michel J et al. | The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico. | 2009 | Mar Drugs | pmid:19370170 |
| Vallabhaneni R and Wurtzel ET | Timing and biosynthetic potential for carotenoid accumulation in genetically diverse germplasm of maize. | 2009 | Plant Physiol. | pmid:19346441 |
| Liu Q et al. | Transcriptome analysis of a spontaneous mutant in sweet orange [Citrus sinensis (L.) Osbeck] during fruit development. | 2009 | J. Exp. Bot. | pmid:19218315 |
| Xu Q et al. | Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant. | 2009 | BMC Genomics | pmid:19922663 |
| Yamada Y et al. | Efficient in vitro synthesis of cis-polyisoprenes using a thermostable cis-prenyltransferase from a hyperthermophilic archaeon Thermococcus kodakaraensis. | 2009 | J. Biotechnol. | pmid:19583987 |
| Kenny JG et al. | The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. | 2009 | PLoS ONE | pmid:19183815 |
| Nieuwenhuizen NJ et al. | Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa). | 2009 | J. Exp. Bot. | pmid:19516075 |
| Jawaid S et al. | Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). | 2009 | PLoS ONE | pmid:20011597 |
| Chang PK et al. | Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | 2009 | Toxins (Basel) | pmid:22069533 |
| Wang W et al. | Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing. | 2009 | BMC Genomics | pmid:19818120 |
| Ganjewala D et al. | An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. | 2009 | Curr Issues Mol Biol | pmid:19193963 |
| Räikkönen J et al. | Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. | 2009 | Br. J. Pharmacol. | pmid:19371349 |
| Vantourout P et al. | Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen. | 2009 | J. Immunol. | pmid:19710470 |
| Li J et al. | Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. | 2009 | J. Immunol. | pmid:19494338 |
| Mitrofan LM et al. | The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. | 2009 | Bone | pmid:19699819 |
| Suzuki M et al. | Complete blockage of the mevalonate pathway results in male gametophyte lethality. | 2009 | J. Exp. Bot. | pmid:19363204 |
| Balibar CJ et al. | The mevalonate pathway of Staphylococcus aureus. | 2009 | J. Bacteriol. | pmid:19028897 |
| Campos Alberto EJ et al. | Differential effects of tumour necrosis factor-alpha and interleukin-12 on isopentenyl pyrophosphate-stimulated interferon-gamma production by cord blood Vgamma9 T cells. | 2009 | Immunology | pmid:19019091 |
| Lu YP et al. | Different reaction mechanisms for cis- and trans-prenyltransferases. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19103164 |
| Oswald E et al. | Reduced numbers of circulating gammadelta T cells in patients with bullous pemphigoid. | 2009 | Exp. Dermatol. | pmid:19469889 |
| Breccia P et al. | Thiopyrophosphoantigens: solid-phase synthesis and in vitro characterization of a new class of Vgamma9 Vdelta2 T cells activators. | 2009 | J. Med. Chem. | pmid:19453173 |
| Lai D et al. | Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate. | 2009 | Metab. Eng. | pmid:19558961 |
| Qin G et al. | Phosphoantigen-expanded human gammadelta T cells display potent cytotoxicity against monocyte-derived macrophages infected with human and avian influenza viruses. | 2009 | J. Infect. Dis. | pmid:19656068 |
| Kastenmüller G et al. | Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. | 2009 | Genome Biol. | pmid:19284550 |
| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Saikia S and Scott B | Functional analysis and subcellular localization of two geranylgeranyl diphosphate synthases from Penicillium paxilli. | 2009 | Mol. Genet. Genomics | pmid:19529962 |
| Rubio-Aliaga I et al. | Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. | 2009 | PLoS ONE | pmid:19562077 |
| Correia DV et al. | Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. | 2009 | PLoS ONE | pmid:19479075 |
| Vinella D et al. | Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. | 2009 | PLoS Genet. | pmid:19478995 |
| Harada H et al. | Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli. | 2009 | Appl. Microbiol. Biotechnol. | pmid:18836713 |
| Ramsden NL et al. | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. | 2009 | J. Med. Chem. | pmid:19320487 |
| Eberl M et al. | A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. | 2009 | PLoS Pathog. | pmid:19229322 |
| Kroll J et al. | Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. | 2009 | Metab. Eng. | pmid:19558962 |
| French CE | Synthetic biology and biomass conversion: a match made in heaven? | 2009 | J R Soc Interface | pmid:19454530 |
| Whitaker JW et al. | The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. | 2009 | Genome Biol. | pmid:19368726 |