Grove JE et al. |
The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase. |
2000 |
J. Bone Miner. Res. |
pmid:10804029
|
Oh SK et al. |
Molecular cloning, expression, and functional analysis of a cis-prenyltransferase from Arabidopsis thaliana. Implications in rubber biosynthesis. |
2000 |
J. Biol. Chem. |
pmid:10764783
|
Koyama T et al. |
Intersubunit location of the active site of farnesyl diphosphate synthase: reconstruction of active enzymes by hybrid-type heteromeric dimers of site-directed mutants. |
2000 |
Biochemistry |
pmid:10631008
|
Cunillera N et al. |
Spatial and temporal patterns of GUS expression directed by 5' regions of the Arabidopsis thaliana farnesyl diphosphate synthase genes FPS1 and FPS2. |
2000 |
Plant Mol. Biol. |
pmid:11202437
|
Lange BM and Croteau R |
Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10570138
|
Leyes AE and Poulter CD |
Synthesis of (R)-[2-2H]isopentenyl diphosphate and determination of its enantiopurity by 2H NMR spectroscopy in a lyotropic medium. |
1999 |
Org. Lett. |
pmid:10825959
|
Morita CT et al. |
Recognition of nonpeptide prenyl pyrophosphate antigens by human gammadelta T cells. |
1999 |
Microbes Infect. |
pmid:10801228
|
Lange BM and Croteau R |
Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from peppermint. |
1999 |
Arch. Biochem. Biophys. |
pmid:10222052
|
Jomaa H et al. |
Vgamma9/Vdelta2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis. |
1999 |
FEMS Immunol. Med. Microbiol. |
pmid:10497868
|
Ridley RG |
Planting the seeds of new antimalarial drugs. |
1999 |
Science |
pmid:10498534
|
Jomaa H et al. |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. |
1999 |
Science |
pmid:10477522
|
Poccia F et al. |
Phosphoantigen-reactive Vgamma9Vdelta2 T lymphocytes suppress in vitro human immunodeficiency virus type 1 replication by cell-released antiviral factors including CC chemokines. |
1999 |
J. Infect. Dis. |
pmid:10438380
|
Poccia F et al. |
In vivo gammadelta T cell priming to mycobacterial antigens by primary Mycobacterium tuberculosis infection and exposure to nonpeptidic ligands. |
1999 |
Mol. Med. |
pmid:10449808
|
Keller RK and Fliesler SJ |
Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10600541
|
Disch A et al. |
Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714. |
1998 |
Biochem. J. |
pmid:9657979
|
Lange BM et al. |
A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9482845
|
Paseshnichenko VA |
A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. |
1998 |
Biochemistry Mosc. |
pmid:9526105
|
Disch A et al. |
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. |
1998 |
Biochem. J. |
pmid:9531505
|
Schoel B and Kaufmann SH |
Influence of mycobacterial virulence and culture condition on gamma delta T cell activation. |
1998 |
Microb. Pathog. |
pmid:9514640
|
Nagaki M et al. |
Substrate specificity of thermostable farnesyl diphosphate synthase with alkyl group homologs of isopentenyl diphosphate. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9873578
|
Sun Z et al. |
Differential expression of two isopentenyl pyrophosphate isomerases and enhanced carotenoid accumulation in a unicellular chlorophyte. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9736763
|
Contin A et al. |
The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture. |
1998 |
FEBS Lett. |
pmid:9742965
|
Rohmer M |
Isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs? |
1998 |
Prog Drug Res |
pmid:9670778
|
Takahashi S et al. |
A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9707569
|
Bouvier F et al. |
Dedicated roles of plastid transketolases during the early onset of isoprenoid biogenesis in pepper fruits1. |
1998 |
Plant Physiol. |
pmid:9701598
|
Terano T et al. |
Geranylgeranylpyrophosphate plays a key role for the G1 to S transition in vascular smooth muscle cells. |
1998 |
J. Atheroscler. Thromb. |
pmid:10077451
|
Disch A and Rohmer M |
On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. |
1998 |
FEMS Microbiol. Lett. |
pmid:9835029
|
Seto H |
[Non-mevalonate pathway. A new pathway for the biosynthesis of isopentenyl diphosphate]. |
1997 |
Tanpakushitsu Kakusan Koso |
pmid:9404155
|
Hinson DD et al. |
Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways. |
1997 |
J. Lipid Res. |
pmid:9392419
|
GarcÃa VE et al. |
Single-cell cytokine analysis of gamma delta T cell responses to nonpeptide mycobacterial antigens. |
1997 |
J. Immunol. |
pmid:9233629
|
Wesch D et al. |
Comparative analysis of alpha beta and gamma delta T cell activation by Mycobacterium tuberculosis and isopentenyl pyrophosphate. |
1997 |
Eur. J. Immunol. |
pmid:9130649
|
Lichtenthaler HK et al. |
Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. |
1997 |
FEBS Lett. |
pmid:9009212
|
Bürk MR et al. |
Functional inactivation in the whole population of human V gamma 9/V delta 2 T lymphocytes induced by a nonpeptidic antagonist. |
1997 |
J. Exp. Med. |
pmid:8996245
|
Schwender J et al. |
Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. |
1997 |
FEBS Lett. |
pmid:9305746
|
Ohnuma S et al. |
Effects of random mutagenesis in a putative substrate-binding domain of geranylgeranyl diphosphate synthase upon intermediate formation and substrate specificity. |
1997 |
J. Biochem. |
pmid:9163520
|
Sireci G et al. |
Patterns of phosphoantigen stimulation of human Vgamma9/Vdelta2 T cell clones include Th0 cytokines. |
1997 |
Hum. Immunol. |
pmid:9475336
|
Srinivasan V et al. |
Metabolic inhibitors, elicitors, and precursors as tools for probing yield limitation in taxane production by Taxus chinensis cell cultures. |
1996 Jul-Aug |
Biotechnol. Prog. |
pmid:8987474
|
Keller RK |
Squalene synthase inhibition alters metabolism of nonsterols in rat liver. |
1996 |
Biochim. Biophys. Acta |
pmid:8908150
|
Hahn FM et al. |
Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. |
1996 |
Arch. Biochem. Biophys. |
pmid:8806705
|
Sagami H et al. |
Enzymatic formation of dehydrodolichal and dolichal, new products related to yeast dolichol biosynthesis. |
1996 |
J. Biol. Chem. |
pmid:8621629
|
Zhang XD et al. |
Expression of the isopentenyl transferase gene is regulated by auxin in transgenic tobacco tissues. |
1996 |
Transgenic Res. |
pmid:8589740
|
Morita CT et al. |
Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. |
1996 |
Res. Immunol. |
pmid:8876064
|
Re EB et al. |
Co-expression of native and introduced genes reveals cryptic regulation of HMG CoA reductase expression in Arabidopsis. |
1995 |
Plant J. |
pmid:7773308
|
Tanaka Y et al. |
Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. |
1995 |
Nature |
pmid:7753173
|
Runquist M et al. |
Isoprenoid biosynthesis in rat liver mitochondria. Studies on farnesyl pyrophosphate synthase and trans-prenyltransferase. |
1994 |
J. Biol. Chem. |
pmid:8119922
|
Christensen DJ and Poulter CD |
Enzymatic synthesis of isotopically labeled isoprenoid diphosphates. |
1994 |
Bioorg. Med. Chem. |
pmid:7858969
|
Horbach S et al. |
Isoprenoid biosynthesis in bacteria: two different pathways? |
1993 |
FEMS Microbiol. Lett. |
pmid:8405922
|
Giron MD et al. |
Isopentenoid synthesis in eukaryotic cells. An initiating role for post-translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. |
1993 |
Arch. Biochem. Biophys. |
pmid:8097083
|
Sahm H et al. |
Biochemistry and physiology of hopanoids in bacteria. |
1993 |
Adv. Microb. Physiol. |
pmid:8310881
|
Sagami H et al. |
Biosynthesis of prenyl diphosphates by cell-free extracts from mammalian tissues. |
1993 |
J. Biochem. |
pmid:8407862
|
Sagami H et al. |
Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate. |
1993 |
J. Biochem. |
pmid:8407863
|
Sagami H et al. |
Formation of dolichol from dehydrodolichol is catalyzed by NADPH-dependent reductase localized in microsomes of rat liver. |
1993 |
J. Biol. Chem. |
pmid:8486680
|
Rohmer M et al. |
Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate. |
1993 |
Biochem. J. |
pmid:8240251
|
Runquist M et al. |
Biosynthesis of trans,trans,trans-geranylgeranyl diphosphate by the cytosolic fraction from rat tissues. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1632765
|
Koch G et al. |
Posttranslational isoprenylation of rho protein is a prerequisite for its interaction with mastoparan and other amphiphilic agents. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1632782
|
Lutz RJ et al. |
Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. |
1992 |
J. Biol. Chem. |
pmid:1569056
|
Tait RM |
Development of a radiometric spot-wash assay for squalene synthase. |
1992 |
Anal. Biochem. |
pmid:1416027
|
Ericsson J et al. |
Characterization and distribution of cis-prenyl transferase participating in liver microsomal polyisoprenoid biosynthesis. |
1991 |
Eur. J. Biochem. |
pmid:1765092
|
Crick DC et al. |
Characterization and localization of a long-chain isoprenyltransferase activity in porcine brain: proposed role in the biosynthesis of dolichyl phosphate. |
1991 |
J. Neurochem. |
pmid:1895109
|
Zhou D and White RH |
Early steps of isoprenoid biosynthesis in Escherichia coli. |
1991 |
Biochem. J. |
pmid:1996960
|
Ding VD et al. |
Purification and characterization of recombinant human farnesyl diphosphate synthase expressed in Escherichia coli. |
1991 |
Biochem. J. |
pmid:2018485
|
Shimizu S et al. |
Possible involvement of 3-hydroxymethylglutaryl-CoA reductase in determining the side-chain length of ubiquinone in rat heart. |
1991 |
Arch. Biochem. Biophys. |
pmid:1846516
|
Schafer WR et al. |
Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. |
1990 |
Science |
pmid:2204115
|
Fujisaki S et al. |
Cloning and nucleotide sequence of the ispA gene responsible for farnesyl diphosphate synthase activity in Escherichia coli. |
1990 |
J. Biochem. |
pmid:2089044
|
Mbaya B et al. |
Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria. |
1990 |
Biochem. Biophys. Res. Commun. |
pmid:2268347
|
Armstrong GA et al. |
Genetic and biochemical characterization of carotenoid biosynthesis mutants of Rhodobacter capsulatus. |
1990 |
J. Biol. Chem. |
pmid:2159477
|
Yoshida I et al. |
Formation of a stable and catalytically active complex of the two essential components of hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26. |
1989 |
Biochem. Biophys. Res. Commun. |
pmid:2541701
|
Fujisaki S et al. |
Isolation and characterization of an Escherichia coli mutant having temperature-sensitive farnesyl diphosphate synthase. |
1989 |
J. Bacteriol. |
pmid:2676985
|
Ohnuma S et al. |
Kinetic studies on the prenyl chain elongation by undecaprenyl diphosphate synthase with artificial substrate homologues. |
1989 |
FEBS Lett. |
pmid:2509247
|
Heide L and Berger U |
Partial purification and properties of geranyl pyrophosphate synthase from Lithospermum erythrorhizon cell cultures. |
1989 |
Arch. Biochem. Biophys. |
pmid:2774555
|
Croteau R and Purkett PT |
Geranyl pyrophosphate synthase: characterization of the enzyme and evidence that this chain-length specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis). |
1989 |
Arch. Biochem. Biophys. |
pmid:2730002
|
Sagami H et al. |
The biosynthesis of dehydrodolichyl phosphates by rat liver microsomes. |
1989 |
Biochim. Biophys. Acta |
pmid:2930770
|
Dennis MS and Light DR |
Rubber elongation factor from Hevea brasiliensis. Identification, characterization, and role in rubber biosynthesis. |
1989 |
J. Biol. Chem. |
pmid:2681199
|
Anderson MS et al. |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae. |
1989 |
J. Biol. Chem. |
pmid:2681212
|
Light DR and Dennis MS |
Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis. |
1989 |
J. Biol. Chem. |
pmid:2808388
|
Light DR et al. |
Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzyme stereospecificity. |
1989 |
J. Biol. Chem. |
pmid:2808389
|
Yoshida I et al. |
Protection of hexaprenyl-diphosphate synthase of Micrococcus luteus B-P 26 against inactivation by sulphydryl reagents and arginine-specific reagents. |
1989 |
Biochim. Biophys. Acta |
pmid:2539196
|
Madhavan S et al. |
Stimulation of Isopentenyl Pyrophosphate Incorporation into Polyisoprene in Extracts from Guayule Plants (Parthenium argentatum Gray) by Low Temperature and 2-(3,4-Dichlorophenoxy) Triethylamine. |
1989 |
Plant Physiol. |
pmid:16666574
|
Gotoh T et al. |
Different roles of the diphosphate moieties of allylic and homoallylic diphosphates in prenyltransferase reaction. |
1988 |
Biochem. Biophys. Res. Commun. |
pmid:3178843
|
Gonzalez-Pacanowska D et al. |
Influence of cholestyramine feeding on mevalonate-activating enzymes. |
1988 |
Enzyme |
pmid:2840276
|
Mettal U et al. |
Biosynthesis of monoterpene hydrocarbons by isolated chromoplasts from daffodil flowers. |
1988 |
Eur. J. Biochem. |
pmid:3338457
|
Bruenger E and Rilling HC |
Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. |
1988 |
Anal. Biochem. |
pmid:3189812
|
Brinkhaus FL and Rilling HC |
Purification of geranylgeranyl diphosphate synthase from Phycomyces blakesleanus. |
1988 |
Arch. Biochem. Biophys. |
pmid:3190245
|
Muehlbacher M and Poulter CD |
Isopentenyl-diphosphate isomerase: inactivation of the enzyme with active-site-directed irreversible inhibitors and transition-state analogues. |
1988 |
Biochemistry |
pmid:3207678
|
Ito M et al. |
Stereochemical analysis of prenyltransferase reactions leading to (Z)- and (E)-polyprenyl chains. |
1987 |
Biochemistry |
pmid:3117106
|
Baba T et al. |
Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. |
1987 |
Arch. Biochem. Biophys. |
pmid:3813545
|
Reardon JE and Abeles RH |
Inhibition of cholesterol biosynthesis by fluorinated mevalonate analogues. |
1987 |
Biochemistry |
pmid:3663621
|
Adair WL and Cafmeyer N |
Characterization of the Saccharomyces cerevisiae cis-prenyltransferase required for dolichyl phosphate biosynthesis. |
1987 |
Arch. Biochem. Biophys. |
pmid:3322197
|
Schulze-Siebert D and Schultz G |
beta-Carotene Synthesis in Isolated Spinach Chloroplasts : Its Tight Linkage to Photosynthetic Carbon Metabolism. |
1987 |
Plant Physiol. |
pmid:16665589
|
Havel C et al. |
Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. |
1986 |
J. Biol. Chem. |
pmid:3733706
|
Ishii K et al. |
A novel prenyltransferase from Paracoccus denitrificans. |
1986 |
Biochem. J. |
pmid:3707524
|
Fujisaki S et al. |
Biosynthesis of isoprenoids in intact cells of Escherichia coli. |
1986 |
J. Biochem. |
pmid:3519600
|
Fujisaki S et al. |
Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis. |
1986 |
J. Biochem. |
pmid:3519603
|
Reardon JE and Abeles RH |
Mechanism of action of isopentenyl pyrophosphate isomerase: evidence for a carbonium ion intermediate. |
1986 |
Biochemistry |
pmid:3022798
|
Dudley MW et al. |
Biosynthesis of the Macrocyclic Diterpene Casbene in Castor Bean (Ricinus communis L.) Seedlings : Changes in Enzyme Levels Induced by Fungal Infection and Intracellular Localization of the Pathway. |
1986 |
Plant Physiol. |
pmid:16664817
|
Dudley MW et al. |
Biosynthesis of the Macrocyclic Diterpene Casbene in Castor Bean (Ricinus communis L.) Seedlings : The Purification and Properties of Farnesyl Transferase from Elicited Seedlings. |
1986 |
Plant Physiol. |
pmid:16664818
|
Macrae S et al. |
Rubber production in guayule: determination of rubber producing potential. |
1986 |
Plant Physiol. |
pmid:16664938
|
Baba T et al. |
Photoaffinity labeling of undecaprenyl pyrophosphate synthetase with a farnesyl pyrophosphate analogue. |
1985 |
J. Biol. Chem. |
pmid:3897217
|
Allen CM and Baba T |
Photolabile analogs of the allylic pyrophosphate substrate of prenyltransferases. |
1985 |
Meth. Enzymol. |
pmid:4021809
|
Lee CS and O'Sullivan WJ |
Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase. |
1985 |
Biochim. Biophys. Acta |
pmid:2983770
|