MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Liu T and Khosla C | Chemistry. A balancing act for Taxol precursor pathways in E. coli. | 2010 | Science | pmid:20929799 |
Ajikumar PK et al. | Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli. | 2010 | Science | pmid:20929806 |
Christianson DW | Chemistry. Roots of biosynthetic diversity. | 2007 | Science | pmid:17412944 |
Schafer WR et al. | Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. | 1990 | Science | pmid:2204115 |
Fischbach MA and Walsh CT | Biochemistry. Directing biosynthesis. | 2006 | Science | pmid:17068249 |
Ridley RG | Planting the seeds of new antimalarial drugs. | 1999 | Science | pmid:10498534 |
Jomaa H et al. | Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. | 1999 | Science | pmid:10477522 |
Morita CT et al. | Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system. | 2000 | Springer Semin. Immunopathol. | pmid:11116953 |
Seto H | [Non-mevalonate pathway. A new pathway for the biosynthesis of isopentenyl diphosphate]. | 1997 | Tanpakushitsu Kakusan Koso | pmid:9404155 |
Pazianas M et al. | Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis. | 2010 | Ther Clin Risk Manag | pmid:20668715 |