|
|
|
|
pmid:
|
Terano T et al. |
Geranylgeranylpyrophosphate plays a key role for the G1 to S transition in vascular smooth muscle cells. |
1998 |
J. Atheroscler. Thromb. |
pmid:10077451
|
Lange BM and Croteau R |
Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from peppermint. |
1999 |
Arch. Biochem. Biophys. |
pmid:10222052
|
Poccia F et al. |
Phosphoantigen-reactive Vgamma9Vdelta2 T lymphocytes suppress in vitro human immunodeficiency virus type 1 replication by cell-released antiviral factors including CC chemokines. |
1999 |
J. Infect. Dis. |
pmid:10438380
|
Poccia F et al. |
In vivo gammadelta T cell priming to mycobacterial antigens by primary Mycobacterium tuberculosis infection and exposure to nonpeptidic ligands. |
1999 |
Mol. Med. |
pmid:10449808
|
Jomaa H et al. |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. |
1999 |
Science |
pmid:10477522
|
Jomaa H et al. |
Vgamma9/Vdelta2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis. |
1999 |
FEMS Immunol. Med. Microbiol. |
pmid:10497868
|
Ridley RG |
Planting the seeds of new antimalarial drugs. |
1999 |
Science |
pmid:10498534
|
Lange BM and Croteau R |
Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10570138
|
Keller RK and Fliesler SJ |
Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10600541
|
Cipriani B et al. |
Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines. |
2000 |
Blood |
pmid:10607682
|
Bergstrom JD et al. |
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. |
2000 |
Arch. Biochem. Biophys. |
pmid:10620343
|
Koyama T et al. |
Intersubunit location of the active site of farnesyl diphosphate synthase: reconstruction of active enzymes by hybrid-type heteromeric dimers of site-directed mutants. |
2000 |
Biochemistry |
pmid:10631008
|
Kuzuyama T et al. |
Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis. |
2000 |
J. Bacteriol. |
pmid:10648511
|
Dairi T et al. |
Cloning of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from terpenoid antibiotic-producing Streptomyces strains. |
2000 |
Mol. Gen. Genet. |
pmid:10660057
|
Cane DE |
Perspectives: biosynthetic pathways. Biosynthesis meets bioinformatics. |
2000 |
Science |
pmid:10691559
|
Charon L et al. |
Deuterium-labelled isotopomers of 2-C-methyl-D-erythritol as tools for the elucidation of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. |
2000 |
Biochem. J. |
pmid:10698701
|
Cunningham FX and Gantt E |
Identification of multi-gene families encoding isopentenyl diphosphate isomerase in plants by heterologous complementation in Escherichia coli. |
2000 |
Plant Cell Physiol. |
pmid:10750717
|
Oh SK et al. |
Molecular cloning, expression, and functional analysis of a cis-prenyltransferase from Arabidopsis thaliana. Implications in rubber biosynthesis. |
2000 |
J. Biol. Chem. |
pmid:10764783
|
Kuzuyama T et al. |
Characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme involved in isopentenyl diphosphate biosynthesis, and identification of its catalytic amino acid residues. |
2000 |
J. Biol. Chem. |
pmid:10787409
|
Morita CT et al. |
Recognition of nonpeptide prenyl pyrophosphate antigens by human gammadelta T cells. |
1999 |
Microbes Infect. |
pmid:10801228
|
Matthews PD and Wurtzel ET |
Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase. |
2000 |
Appl. Microbiol. Biotechnol. |
pmid:10803894
|
Grove JE et al. |
The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase. |
2000 |
J. Bone Miner. Res. |
pmid:10804029
|
RodrÃguez-Concepción M et al. |
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. |
2000 |
FEBS Lett. |
pmid:10818234
|
Leyes AE and Poulter CD |
Synthesis of (R)-[2-2H]isopentenyl diphosphate and determination of its enantiopurity by 2H NMR spectroscopy in a lyotropic medium. |
1999 |
Org. Lett. |
pmid:10825959
|
Kang H et al. |
Identification of natural rubber and characterization of rubber biosynthetic activity in fig tree. |
2000 |
Plant Physiol. |
pmid:10889262
|
Takagi M et al. |
A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. |
2000 |
J. Bacteriol. |
pmid:10894721
|
Wilding EI et al. |
Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci. |
2000 |
J. Bacteriol. |
pmid:10894743
|
Sicard H and Fournie JJ |
Metabolic routes as targets for immunological discrimination of host and parasite. |
2000 |
Infect. Immun. |
pmid:10899832
|
Kojima N et al. |
Geranylgeranyl diphosphate synthases from Scoparia dulcis and Croton sublyratus. cDNA cloning, functional expression, and conversion to a farnesyl diphosphate synthase. |
2000 |
Chem. Pharm. Bull. |
pmid:10923851
|
Martini F et al. |
gammadelta T-cell anergy in human immunodeficiency virus-infected persons with opportunistic infections and recovery after highly active antiretroviral therapy. |
2000 |
Immunology |
pmid:10929075
|
Hirai N et al. |
Biosynthesis of abscisic acid by the non-mevalonate pathway in plants, and by the mevalonate pathway in fungi. |
2000 |
Biosci. Biotechnol. Biochem. |
pmid:10945263
|
Wang P and Malkovsky M |
Different roles of the CD2 and LFA-1 T-cell co-receptors for regulating cytotoxic, proliferative, and cytokine responses of human V gamma 9/V delta 2 T cells. |
2000 |
Mol. Med. |
pmid:10965495
|
Boucher Y and Doolittle WF |
The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways. |
2000 |
Mol. Microbiol. |
pmid:10972794
|
Pan JJ et al. |
Product distribution and pre-steady-state kinetic analysis of Escherichia coli undecaprenyl pyrophosphate synthase reaction. |
2000 |
Biochemistry |
pmid:10978182
|
Itoh D et al. |
Nonequivalent labeling of the phytyl side chain of chlorophyll a in callus of the hornwort Anthoceros punctatus. |
2000 |
J. Nat. Prod. |
pmid:10978203
|
Fraser PD et al. |
Phytoene synthase from tomato (Lycopersicon esculentum) chloroplasts--partial purification and biochemical properties. |
2000 |
Planta |
pmid:10987554
|
Cunningham FX et al. |
Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. |
2000 |
J. Bacteriol. |
pmid:11004185
|
Grolle S et al. |
Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. |
2000 |
FEMS Microbiol. Lett. |
pmid:11004410
|
Miller B et al. |
Functional involvement of a deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. |
2000 |
FEBS Lett. |
pmid:11007968
|
Plochocka D et al. |
The role of ERG20 gene (encoding yeast farnesyl diphosphate synthase) mutation in long dolichol formation. Molecular modeling of FPP synthase. |
2000 |
Biochimie |
pmid:11018290
|
Zhang YW et al. |
Chain length determination of prenyltransferases: both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. |
2000 |
Biochemistry |
pmid:11027152
|
Smit A and Mushegian A |
Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. |
2000 |
Genome Res. |
pmid:11042147
|
Pan JJ et al. |
Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysis. |
2000 |
Biochemistry |
pmid:11076526
|
Lange BM et al. |
Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11078528
|
Ladygin VG |
Biosynthesis of carotenoids in plastids of plants. |
2000 |
Biochemistry Mosc. |
pmid:11092953
|
Reed BC and Rilling HC |
Crystallization and partial characterization of prenyltransferase from avian liver. |
1975 |
Biochemistry |
pmid:1109590
|
Fujikura K et al. |
Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26. |
2000 |
J. Biochem. |
pmid:11098133
|
Olivier LM et al. |
Identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes. AA-CoA thiolase, hmg-coa synthase, MPPD, and FPP synthase. |
2000 |
J. Lipid Res. |
pmid:11108725
|
Vance DE and Van den Bosch H |
Cholesterol in the year 2000. |
2000 |
Biochim. Biophys. Acta |
pmid:11111073
|
Olivier LM and Krisans SK |
Peroxisomal protein targeting and identification of peroxisomal targeting signals in cholesterol biosynthetic enzymes. |
2000 |
Biochim. Biophys. Acta |
pmid:11111079
|
Stanley Fernandez SM et al. |
Farnesyl diphosphate synthase. Altering the catalytic site to select for geranyl diphosphate activity. |
2000 |
Biochemistry |
pmid:11112517
|
Hahn FM et al. |
1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. |
2001 |
J. Bacteriol. |
pmid:11114895
|
Campos N et al. |
Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. |
2001 |
Biochem. J. |
pmid:11115399
|
Morita CT et al. |
Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system. |
2000 |
Springer Semin. Immunopathol. |
pmid:11116953
|
Jones KL et al. |
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. |
2000 |
Metab. Eng. |
pmid:11120644
|
Huang L and Pardee AB |
Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment. |
2000 |
Mol. Med. |
pmid:11126200
|
Schulbach MC et al. |
Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis. |
2001 |
J. Biol. Chem. |
pmid:11152452
|
Wungsintaweekul J et al. |
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. |
2001 |
Eur. J. Biochem. |
pmid:11168365
|
Lichtenthaler HK |
Non-mevalonate isoprenoid biosynthesis: enzymes, genes and inhibitors. |
2000 |
Biochem. Soc. Trans. |
pmid:11171208
|
Eisenreich W et al. |
Deoxyxylulose phosphate pathway to terpenoids. |
2001 |
Trends Plant Sci. |
pmid:11173292
|
Kim SW and Keasling JD |
Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production. |
2001 |
Biotechnol. Bioeng. |
pmid:11180061
|
|
|
|
|
pmid:11181565
|
Cunillera N et al. |
Spatial and temporal patterns of GUS expression directed by 5' regions of the Arabidopsis thaliana farnesyl diphosphate synthase genes FPS1 and FPS2. |
2000 |
Plant Mol. Biol. |
pmid:11202437
|
Sitthithaworn W et al. |
Geranylgeranyl diphosphate synthase from Scoparia dulcis and Croton sublyratus. Plastid localization and conversion to a farnesyl diphosphate synthase by mutagenesis. |
2001 |
Chem. Pharm. Bull. |
pmid:11217109
|
Altincicek B et al. |
Cutting edge: human gamma delta T cells are activated by intermediates of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis. |
2001 |
J. Immunol. |
pmid:11238603
|
Estévez JM et al. |
1-Deoxy-D-xylulose-5-phosphate synthase, a limiting enzyme for plastidic isoprenoid biosynthesis in plants. |
2001 |
J. Biol. Chem. |
pmid:11264287
|
Altincicek B et al. |
GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. |
2001 |
J. Bacteriol. |
pmid:11274098
|
Lafont V et al. |
Isopentenyl pyrophosphate, a mycobacterial non-peptidic antigen, triggers delayed and highly sustained signaling in human gamma delta T lymphocytes without inducing eown-modulation of T cell antigen receptor. |
2001 |
J. Biol. Chem. |
pmid:11278429
|
Schwender J et al. |
Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. |
2001 |
Planta |
pmid:11289606
|
|
|
|
|
pmid:11292074
|
Kharel Y et al. |
Identification of Significant residues for homoallylic substrate binding of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase. |
2001 |
J. Biol. Chem. |
pmid:11346651
|
Tholl D et al. |
Partial purification and characterization of the short-chain prenyltransferases, gernayl diphospate synthase and farnesyl diphosphate synthase, from Abies grandis (grand fir). |
2001 |
Arch. Biochem. Biophys. |
pmid:11368347
|
Lafont V et al. |
Production of TNF-alpha by human V gamma 9V delta 2 T cells via engagement of Fc gamma RIIIA, the low affinity type 3 receptor for the Fc portion of IgG, expressed upon TCR activation by nonpeptidic antigen. |
2001 |
J. Immunol. |
pmid:11390467
|
|
|
|
|
pmid:11408165
|
Morita CT et al. |
Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human gamma delta T cells. |
2001 |
J. Immunol. |
pmid:11418629
|
Sharman A |
The many uses of a genome sequence. |
2001 |
Genome Biol. |
pmid:11423005
|
|
|
|
|
pmid:11430985
|
|
|
|
|
pmid:11432933
|
Kakinuma K et al. |
New approach to multiply deuterated isoprenoids using triply engineered Escherichia coli and its potential as a tool for mechanistic enzymology. |
2001 |
J. Am. Chem. Soc. |
pmid:11456682
|
Zeidler J and Lichtenthaler HK |
Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. |
2001 |
Planta |
pmid:11469599
|
|
|
|
|
pmid:11514159
|
Hamano Y et al. |
Cloning of a gene cluster encoding enzymes responsible for the mevalonate pathway from a terpenoid-antibiotic-producing Streptomyces strain. |
2001 |
Biosci. Biotechnol. Biochem. |
pmid:11515548
|
Cipriani B et al. |
Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation. |
2001 |
J. Immunol. |
pmid:11544338
|
Huang Q et al. |
Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. |
2001 |
Bioorg. Med. Chem. |
pmid:11553461
|
Lange BM et al. |
Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. |
2001 |
Plant Physiol. |
pmid:11553758
|
Evans PS et al. |
In vitro stimulation with a non-peptidic alkylphosphate expands cells expressing Vgamma2-Jgamma1.2/Vdelta2 T-cell receptors. |
2001 |
Immunology |
pmid:11576216
|
Phan RM and Poulter CD |
Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. |
2001 |
J. Org. Chem. |
pmid:11578224
|
Rohdich F et al. |
The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates. |
2001 |
Curr Opin Chem Biol |
pmid:11578926
|
Nakamura A et al. |
Two distinct isopentenyl diphosphate isomerases in cytosol and plastid are differentially induced by environmental stresses in tobacco. |
2001 |
FEBS Lett. |
pmid:11591371
|
|
|
|
|
pmid:11672736
|
Feurle J et al. |
Escherichia coli produces phosphoantigens activating human gamma delta T cells. |
2002 |
J. Biol. Chem. |
pmid:11675382
|
Cornish K et al. |
Rubber molecular weight regulation, in vitro, in plant species that produce high and low molecular weights in vivo. |
2000 |
Biomacromolecules |
pmid:11710193
|
Daubenberger CA et al. |
Functional and structural similarity of V gamma 9V delta 2 T cells in humans and Aotus monkeys, a primate infection model for Plasmodium falciparum malaria. |
2001 |
J. Immunol. |
pmid:11714808
|
|
|
|
|
pmid:11722180
|
Chen YH et al. |
Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants. |
2002 |
J. Biol. Chem. |
pmid:11744728
|
Wesch D et al. |
Differentiation of resting human peripheral blood gamma delta T cells toward Th1- or Th2-phenotype. |
2001 |
Cell. Immunol. |
pmid:11748927
|
Yang D et al. |
Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily. |
2002 |
J. Biol. Chem. |
pmid:11751891
|
Han YS et al. |
Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. |
2002 |
Phytochemistry |
pmid:11754943
|
|
|
|
|
pmid:11785983
|