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Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. |
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Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. |
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J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using (1)H-(31)P-(31)P correlation NMR spectroscopy. |
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Mol Biosyst |
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Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature. |
2009 |
Genome Biol Evol |
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Transcript and proteomic analysis of developing white lupin (Lupinus albus L.) roots. |
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BMC Plant Biol. |
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Flux-sum analysis: a metabolite-centric approach for understanding the metabolic network. |
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BMC Syst Biol |
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Int J Microbiol |
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2009 |
Biol. Direct |
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2009 |
Naturwissenschaften |
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Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. |
2009 |
PLoS ONE |
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BMC Immunol. |
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Biosci. Biotechnol. Biochem. |
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Quantification of dolichol in the human lens with different types of cataracts. |
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Mol. Vis. |
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The small subunit of snapdragon geranyl diphosphate synthase modifies the chain length specificity of tobacco geranylgeranyl diphosphate synthase in planta. |
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Plant Cell |
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Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study. |
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J Ovarian Res |
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A comprehensive bioinformatics analysis of the Nudix superfamily in Arabidopsis thaliana. |
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Comp. Funct. Genomics |
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Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH). |
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BMC Genomics |
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The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico. |
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Mar Drugs |
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Conformational dynamics of the flexible catalytic loop in Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase. |
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Chem Biol Drug Des |
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Efficient in vitro synthesis of cis-polyisoprenes using a thermostable cis-prenyltransferase from a hyperthermophilic archaeon Thermococcus kodakaraensis. |
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Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5. |
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BMC Genomics |
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Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa). |
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J. Exp. Bot. |
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Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. |
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Int J Mol Sci |
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Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). |
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PLoS ONE |
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2009 |
Toxins (Basel) |
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Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. |
2009 |
Interdiscip Perspect Infect Dis |
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An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. |
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Curr Issues Mol Biol |
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Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. |
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Br. J. Pharmacol. |
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J. Immunol. |
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The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. |
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Complete blockage of the mevalonate pathway results in male gametophyte lethality. |
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Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate. |
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Metab. Eng. |
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Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells. |
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Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. |
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Biochem. Pharmacol. |
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A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites. |
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Plant Cell |
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Functional analysis and subcellular localization of two geranylgeranyl diphosphate synthases from Penicillium paxilli. |
2009 |
Mol. Genet. Genomics |
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Gene expression profiling in susceptible interaction of grapevine with its fungal pathogen Eutypa lata: extending MapMan ontology for grapevine. |
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BMC Plant Biol. |
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New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition. |
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Cell. Mol. Life Sci. |
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Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. |
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PLoS ONE |
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Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. |
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PLoS ONE |
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Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. |
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PLoS Genet. |
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New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. |
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J. Biol. Chem. |
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Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology. |
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Metab. Eng. |
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Synthetic biology and biomass conversion: a match made in heaven? |
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J R Soc Interface |
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Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. |
2009 |
BMC Genomics |
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The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. |
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Genome Biol. |
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