Lin YS et al. |
Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells. |
2012 |
J. Med. Chem. |
pmid:22390415
|
Holte D et al. |
An approach to mimicking the sesquiterpene cyclase phase by nickel-promoted diene/alkyne cooligomerization. |
2012 |
J. Org. Chem. |
pmid:22229741
|
Mabanglo MF et al. |
The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase. |
2012 |
Biochemistry |
pmid:22148590
|
Modi ND and Lentzsch S |
Bisphosphonates as antimyeloma drugs. |
2012 |
Leukemia |
pmid:22005788
|
Park J et al. |
Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. |
2012 |
BMC Struct. Biol. |
pmid:23234314
|
Soriano-Sarabia N et al. |
Primary MHC-class II(+) cells are necessary to promote resting Vδ2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate. |
2012 |
J. Immunol. |
pmid:23105138
|
Van Laar TA et al. |
Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. |
2012 |
PLoS ONE |
pmid:22675445
|
Liu D et al. |
The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected]. |
2012 |
PLoS ONE |
pmid:22567134
|
Yang J et al. |
Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. |
2012 |
PLoS ONE |
pmid:22558074
|
Mosqueda J et al. |
Current advances in detection and treatment of babesiosis. |
2012 |
Curr. Med. Chem. |
pmid:22360483
|
Span I et al. |
Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. |
2012 |
J. Mol. Biol. |
pmid:22137895
|
Xu W et al. |
A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase. |
2012 |
Biochemistry |
pmid:22646150
|
Testa CA and Johnson LJ |
A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. |
2012 |
Antimicrob. Agents Chemother. |
pmid:22777049
|
Song AA et al. |
Functional expression of an orchid fragrance gene in Lactococcus lactis. |
2012 |
Int J Mol Sci |
pmid:22408409
|
Green SA et al. |
Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). |
2012 |
J. Exp. Bot. |
pmid:22162874
|
Zhang YL and Li ZX |
Functional analysis and molecular docking identify two active short-chain prenyltransferases in the green peach aphid, Myzus persicae. |
2012 |
Arch. Insect Biochem. Physiol. |
pmid:22696503
|
Mohanta TK et al. |
Ginkgo biloba responds to herbivory by activating early signaling and direct defenses. |
2012 |
PLoS ONE |
pmid:22448229
|
Diaz ME et al. |
Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. |
2012 |
Insect Biochem. Mol. Biol. |
pmid:22782071
|
Kuzuyama T and Seto H |
Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. |
2012 |
Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. |
pmid:22450534
|
Dozier JK and Distefano MD |
An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. |
2012 |
Anal. Biochem. |
pmid:22085443
|
Caballero MC et al. |
Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. |
2012 |
Mol. Biochem. Parasitol. |
pmid:22057350
|
Fowler DW et al. |
Mycobacteria activate γδ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy. |
2012 |
Cancer Immunol. Immunother. |
pmid:22002242
|
Quinzii CM et al. |
Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts. |
2012 |
PLoS ONE |
pmid:22359546
|
Ariyawutthiphan O et al. |
Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. |
2012 |
Acta Crystallogr. D Biol. Crystallogr. |
pmid:23090405
|
Hussain MS et al. |
Current approaches toward production of secondary plant metabolites. |
2012 |
J Pharm Bioallied Sci |
pmid:22368394
|
Lamsen EN and Atsumi S |
Recent progress in synthetic biology for microbial production of C3-C10 alcohols. |
2012 |
Front Microbiol |
pmid:22701113
|
Chow KS et al. |
Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex. |
2012 |
J. Exp. Bot. |
pmid:22162870
|
Rad SA et al. |
Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains. |
2012 |
World J. Microbiol. Biotechnol. |
pmid:22806807
|
Fatima T et al. |
Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. |
2012 |
PLoS ONE |
pmid:22558083
|
Kumar M et al. |
Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. |
2012 |
Exp Diabetes Res |
pmid:22611376
|
Barta ML et al. |
Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. |
2012 |
Biochemistry |
pmid:22734632
|
Teng KH and Liang PH |
Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis. |
2012 |
Bioorg. Chem. |
pmid:21993493
|
Chou HH and Keasling JD |
Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. |
2012 |
Appl. Environ. Microbiol. |
pmid:22941086
|
Cornish K and Xie W |
Natural rubber biosynthesis in plants: rubber transferase. |
2012 |
Meth. Enzymol. |
pmid:22999170
|
Guirimand G et al. |
Triple subcellular targeting of isopentenyl diphosphate isomerases encoded by a single gene. |
2012 |
Plant Signal Behav |
pmid:22951398
|
Zhang J et al. |
Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases. |
2012 |
Int. J. Biochem. Cell Biol. |
pmid:22982238
|
Post J et al. |
Laticifer-specific cis-prenyltransferase silencing affects the rubber, triterpene, and inulin content of Taraxacum brevicorniculatum. |
2012 |
Plant Physiol. |
pmid:22238421
|
Suzuki N et al. |
Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. |
2012 |
Planta |
pmid:22729820
|
Raina M et al. |
Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis. |
2012 |
FEBS Lett. |
pmid:22683511
|
Ma YG et al. |
Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells. |
2012 |
PLoS ONE |
pmid:22655048
|
Jonnalagadda V et al. |
Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. |
2012 |
J. Am. Chem. Soc. |
pmid:22471428
|
Wurtzel ET et al. |
Maize provitamin a carotenoids, current resources, and future metabolic engineering challenges. |
2012 |
Front Plant Sci |
pmid:22645578
|
Teng KH and Liang PH |
Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis. |
2012 |
Mol. Membr. Biol. |
pmid:22471620
|
Yokoi T et al. |
Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli. |
2012 |
Archaea |
pmid:22645416
|
Förster F et al. |
Transcriptome analysis in tardigrade species reveals specific molecular pathways for stress adaptations. |
2012 |
Bioinform Biol Insights |
pmid:22563243
|
Berthelot K et al. |
Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis. |
2012 |
Biochimie |
pmid:22503704
|
Wan L et al. |
De novo transcriptomic analysis of an oleaginous microalga: pathway description and gene discovery for production of next-generation biofuels. |
2012 |
PLoS ONE |
pmid:22536352
|
Mabanglo MF et al. |
Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity. |
2012 |
ACS Chem. Biol. |
pmid:22533411
|
Bendersky A et al. |
Cellular interactions of synovial fluid γδ T cells in juvenile idiopathic arthritis. |
2012 |
J. Immunol. |
pmid:22450805
|
Lei A et al. |
Expression of fatty acid synthesis genes and fatty acid accumulation in haematococcus pluvialis under different stressors. |
2012 |
Biotechnol Biofuels |
pmid:22448811
|