Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Fuse M et al. Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. 2004 Biochem. Biophys. Res. Commun. pmid:14985133
Fraser PD and Bramley PM The biosynthesis and nutritional uses of carotenoids. 2004 Prog. Lipid Res. pmid:15003396
Yamashita S et al. Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae. 2004 Eur. J. Biochem. pmid:15009187
Chojnacki T Preparation of tritium-labeled 3-methyl-3-buten-1[3H]-yl diphosphate (3H-isopentenyl diphosphate). 2004 Meth. Enzymol. pmid:15038965
Chang SY et al. Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies. 2004 Protein Sci. pmid:15044730
Burlat V et al. Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites. 2004 Plant J. pmid:15053766
Dhiman RK et al. Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. 2004 J. Lipid Res. pmid:15060088
Ralph SA et al. Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. 2004 Nat. Rev. Microbiol. pmid:15083156
pmid:15110773
Kalyan S and Chow AW Human peripheral gammadelta T cells potentiate the early proinflammatory cytokine response to staphylococcal toxic shock syndrome toxin-1. 2004 J. Infect. Dis. pmid:15122526
Glazko GV and Mushegian AR Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns. 2004 Genome Biol. pmid:15128446
Chau M and Croteau R Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. 2004 Arch. Biochem. Biophys. pmid:15178487
pmid:15196010
Kunzmann V et al. Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons. 2004 Immunology pmid:15196204
pmid:15197467
Laupitz R et al. Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. 2004 Eur. J. Biochem. pmid:15206931
Poliquin K et al. Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. 2004 J. Bacteriol. pmid:15231801
Verjans GM et al. Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes. 2004 J. Infect. Dis. pmid:15243921
pmid:15257386
pmid:15279616