| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Enfissi EM et al. | Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. | 2005 | Plant Biotechnol. J. | pmid:17168896 |
| Flügge UI and Gao W | Transport of isoprenoid intermediates across chloroplast envelope membranes. | 2005 | Plant Biol (Stuttg) | pmid:15666208 |
| Lopes AA et al. | Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae). | 2007 | Phytochemistry | pmid:17574633 |
| Schmidt A and Gershenzon J | Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). | 2008 | Phytochemistry | pmid:17673268 |
| Carter OA et al. | Monoterpene biosynthesis pathway construction in Escherichia coli. | 2003 | Phytochemistry | pmid:12943759 |
| Han YS et al. | Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. | 2002 | Phytochemistry | pmid:11754943 |
| Lim L and McFadden GI | The evolution, metabolism and functions of the apicoplast. | 2010 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:20124342 |
| Maurice T et al. | Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection. | 2006 | Pharmacol. Biochem. Behav. | pmid:16945406 |
| Wen W and Yu R | Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. | 2011 | Pharmacogn Rev | pmid:22279377 |
| Baikar S and Malpathak N | Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs. | 2010 | Pharmacogn Rev | pmid:22228937 |
| Simonsen HT et al. | Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates. | 2009 | Perspect Medicin Chem | pmid:19812738 |
| Ueno A et al. | Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. | 2013 | Parasitol. Int. | pmid:23276703 |
| Bang S et al. | Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. | 2011 | Pain | pmid:21353389 |
| Silverman SL et al. | Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid. | 2011 | Osteoporos Int | pmid:21116816 |
| Leyes AE and Poulter CD | Synthesis of (R)-[2-2H]isopentenyl diphosphate and determination of its enantiopurity by 2H NMR spectroscopy in a lyotropic medium. | 1999 | Org. Lett. | pmid:10825959 |
| Barkley SJ et al. | Proton exchange in type II isopentenyl diphosphate isomerase. | 2004 | Org. Lett. | pmid:15606125 |
| Xiao Y et al. | Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues. | 2011 | Org. Lett. | pmid:21981393 |
| Kao CL et al. | Stereochemical analysis of isopentenyl diphosphate isomerase type II from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. | 2005 | Org. Lett. | pmid:16321020 |
| Scholte AA and Vederas JC | Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis. | 2006 | Org. Biomol. Chem. | pmid:16467948 |
| Kumari U and Heese K | Cardiovascular dementia - a different perspective. | 2010 | Open Biochem J | pmid:20448820 |