MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Islam M et al. | Dissociation of prelycopersene pyrophosphate synthetase from phytoene synthetase complex of tomato fruit plastids. | 1977 | J. Biol. Chem. | pmid:838727 |
Horbach S et al. | Isoprenoid biosynthesis in bacteria: two different pathways? | 1993 | FEMS Microbiol. Lett. | pmid:8405922 |
Sagami H et al. | Biosynthesis of prenyl diphosphates by cell-free extracts from mammalian tissues. | 1993 | J. Biochem. | pmid:8407862 |
Sagami H et al. | Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate. | 1993 | J. Biochem. | pmid:8407863 |
Brems DN and Rilling HC | Photoaffinity labeling of the catalytic site of prenyltransferase. | 1979 | Biochemistry | pmid:84684 |
Sagami H et al. | Formation of dolichol from dehydrodolichol is catalyzed by NADPH-dependent reductase localized in microsomes of rat liver. | 1993 | J. Biol. Chem. | pmid:8486680 |
Zhang XD et al. | Expression of the isopentenyl transferase gene is regulated by auxin in transgenic tobacco tissues. | 1996 | Transgenic Res. | pmid:8589740 |
Sagami H et al. | Enzymatic formation of dehydrodolichal and dolichal, new products related to yeast dolichol biosynthesis. | 1996 | J. Biol. Chem. | pmid:8621629 |
Hahn FM et al. | Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. | 1996 | Arch. Biochem. Biophys. | pmid:8806705 |
Morita CT et al. | Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. | 1996 | Res. Immunol. | pmid:8876064 |