| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Baker SK and Tarnopolsky MA | Statin-associated neuromyotoxicity. | 2005 | Drugs Today | pmid:16034491 |
| Wouters J et al. | A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase. | 2005 | J. Am. Chem. Soc. | pmid:15643873 |
| Guo RT et al. | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. | 2005 | J. Biol. Chem. | pmid:15788389 |
| Doun SS et al. | Enterococcus faecalis phosphomevalonate kinase. | 2005 | Protein Sci. | pmid:15802646 |
| Wu Z et al. | Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate. | 2005 | J. Am. Chem. Soc. | pmid:16332094 |
| Rohdich F et al. | Isoprenoid biosynthetic pathways as anti-infective drug targets. | 2005 | Biochem. Soc. Trans. | pmid:16042599 |
| Park YC et al. | Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15459799 |
| Seker T et al. | Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15448940 |
| Sabehi G et al. | New insights into metabolic properties of marine bacteria encoding proteorhodopsins. | 2005 | PLoS Biol. | pmid:16008504 |
| Tonhosolo R et al. | Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. | 2005 | Biochem. J. | pmid:15984931 |
| Corvaisier M et al. | V gamma 9V delta 2 T cell response to colon carcinoma cells. | 2005 | J. Immunol. | pmid:16210656 |
| Morikawa S et al. | Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins. | 2005 | J. Atheroscler. Thromb. | pmid:16020911 |
| Sicard H et al. | In vivo immunomanipulation of V gamma 9V delta 2 T cells with a synthetic phosphoantigen in a preclinical nonhuman primate model. | 2005 | J. Immunol. | pmid:16210655 |
| Gil MJ et al. | The Arabidopsis csb3 mutant reveals a regulatory link between salicylic acid-mediated disease resistance and the methyl-erythritol 4-phosphate pathway. | 2005 | Plant J. | pmid:16167903 |
| Poggi A et al. | Regulation of gammadelta T cell survival by soluble HLA-I: involvement of CD8 and activating killer Ig-like receptors. | 2005 | Eur. J. Immunol. | pmid:16114098 |
| Hirooka K et al. | Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15784989 |
| Becker SA and Palsson BØ | Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N315: an initial draft to the two-dimensional annotation. | 2005 | BMC Microbiol. | pmid:15752426 |
| Fujisaki S et al. | Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. | 2005 | J. Biochem. | pmid:15809342 |
| Enfissi EM et al. | Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. | 2005 | Plant Biotechnol. J. | pmid:17168896 |
| Kamińska J et al. | Rsp5 ubiquitin ligase affects isoprenoid pathway and cell wall organization in S. cerevisiae. | 2005 | Acta Biochim. Pol. | pmid:15827618 |
| Kang MJ et al. | Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method. | 2005 | Biotechnol. Bioeng. | pmid:15898075 |
| de Ruyck J et al. | Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16269131 |
| Casetti R et al. | Drug-induced expansion and differentiation of V gamma 9V delta 2 T cells in vivo: the role of exogenous IL-2. | 2005 | J. Immunol. | pmid:16034098 |
| Flügge UI and Gao W | Transport of isoprenoid intermediates across chloroplast envelope membranes. | 2005 | Plant Biol (Stuttg) | pmid:15666208 |
| Chen L et al. | Transcriptional profiling of gamma delta T cells identifies a role for vitamin D in the immunoregulation of the V gamma 9V delta 2 response to phosphate-containing ligands. | 2005 | J. Immunol. | pmid:15879110 |
| Cairo C et al. | The Vgamma2/Vdelta2 T-cell repertoire in Macaca fascicularis: functional responses to phosphoantigen stimulation by the Vgamma2/Jgamma1.2 subset. | 2005 | Immunology | pmid:15885125 |
| Martino A et al. | Complementary function of gamma delta T-lymphocytes and dendritic cells in the response to isopentenyl-pyrophosphate and lipopolysaccharide antigens. | 2005 | J. Clin. Immunol. | pmid:15981088 |
| Mahmud T et al. | A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. | 2005 | Chembiochem | pmid:15619721 |
| Szkopińska A and Płochocka D | Farnesyl diphosphate synthase; regulation of product specificity. | 2005 | Acta Biochim. Pol. | pmid:15827605 |
| Guevara-GarcÃa A et al. | Characterization of the Arabidopsis clb6 mutant illustrates the importance of posttranscriptional regulation of the methyl-D-erythritol 4-phosphate pathway. | 2005 | Plant Cell | pmid:15659625 |
| Yamashita S et al. | Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae. | 2004 | Eur. J. Biochem. | pmid:15009187 |
| Chau M and Croteau R | Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. | 2004 | Arch. Biochem. Biophys. | pmid:15178487 |
| Ralph SA et al. | Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. | 2004 | Nat. Rev. Microbiol. | pmid:15083156 |
| Dhiman RK et al. | Identification of a novel class of omega,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis. | 2004 | J. Lipid Res. | pmid:15060088 |
| Kalyan S and Chow AW | Human peripheral gammadelta T cells potentiate the early proinflammatory cytokine response to staphylococcal toxic shock syndrome toxin-1. | 2004 | J. Infect. Dis. | pmid:15122526 |
| Workalemahu G et al. | Expression and synthesis of fibroblast growth factor-9 in human gammadelta T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-beta1/IL-15. | 2004 | J. Leukoc. Biol. | pmid:14704367 |
| Scholte AA et al. | Synthesis and biological activity of isopentenyl diphosphate analogues. | 2004 | Bioorg. Med. Chem. | pmid:14759736 |
| Ling S et al. | Genoprotective pathways. II. Attenuation of oxidative DNA damage by isopentenyl diphosphate. | 2004 | Mutat. Res. | pmid:15450402 |
| Xiong X et al. | Identification of guinea pig gammadelta T cells and characterization during pulmonary tuberculosis. | 2004 | Vet. Immunol. Immunopathol. | pmid:15451613 |
| Boylston WH et al. | Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. | 2004 | Aging Cell | pmid:15379852 |
| Forsea AM et al. | Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. | 2004 | Br. J. Cancer | pmid:15280922 |
| Kunzmann V et al. | Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons. | 2004 | Immunology | pmid:15196204 |
| Glazko GV and Mushegian AR | Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns. | 2004 | Genome Biol. | pmid:15128446 |
| Burlat V et al. | Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites. | 2004 | Plant J. | pmid:15053766 |
| Raschke M et al. | A high-performance liquid chromatography method for the analysis of intermediates of the deoxyxylulose phosphate pathway. | 2004 | Anal. Biochem. | pmid:15556562 |
| Chojnacki T | Preparation of tritium-labeled 3-methyl-3-buten-1[3H]-yl diphosphate (3H-isopentenyl diphosphate). | 2004 | Meth. Enzymol. | pmid:15038965 |
| Laupitz R et al. | Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. | 2004 | Eur. J. Biochem. | pmid:15206931 |
| Laupitz R et al. | Stereochemical studies on the making and unmaking of isopentenyl diphosphate in different biological systems. | 2004 | Chem. Biodivers. | pmid:17191914 |
| Thompson K and Rogers MJ | Statins prevent bisphosphonate-induced gamma,delta-T-cell proliferation and activation in vitro. | 2004 | J. Bone Miner. Res. | pmid:14969398 |
| Rohdich F et al. | Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate. | 2004 | Bioorg. Chem. | pmid:15381396 |