Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

Cross Reference

Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Simonsen HT et al. Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates. 2009 Perspect Medicin Chem pmid:19812738
Ueno A et al. Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. 2013 Parasitol. Int. pmid:23276703
Bang S et al. Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. 2011 Pain pmid:21353389
Silverman SL et al. Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid. 2011 Osteoporos Int pmid:21116816
Leyes AE and Poulter CD Synthesis of (R)-[2-2H]isopentenyl diphosphate and determination of its enantiopurity by 2H NMR spectroscopy in a lyotropic medium. 1999 Org. Lett. pmid:10825959
Barkley SJ et al. Proton exchange in type II isopentenyl diphosphate isomerase. 2004 Org. Lett. pmid:15606125
Xiao Y et al. Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues. 2011 Org. Lett. pmid:21981393
Kao CL et al. Stereochemical analysis of isopentenyl diphosphate isomerase type II from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. 2005 Org. Lett. pmid:16321020
Scholte AA and Vederas JC Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis. 2006 Org. Biomol. Chem. pmid:16467948
Kumari U and Heese K Cardiovascular dementia - a different perspective. 2010 Open Biochem J pmid:20448820