MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Simonsen HT et al. | Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates. | 2009 | Perspect Medicin Chem | pmid:19812738 |
Ueno A et al. | Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. | 2013 | Parasitol. Int. | pmid:23276703 |
Bang S et al. | Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. | 2011 | Pain | pmid:21353389 |
Silverman SL et al. | Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid. | 2011 | Osteoporos Int | pmid:21116816 |
Leyes AE and Poulter CD | Synthesis of (R)-[2-2H]isopentenyl diphosphate and determination of its enantiopurity by 2H NMR spectroscopy in a lyotropic medium. | 1999 | Org. Lett. | pmid:10825959 |
Barkley SJ et al. | Proton exchange in type II isopentenyl diphosphate isomerase. | 2004 | Org. Lett. | pmid:15606125 |
Xiao Y et al. | Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues. | 2011 | Org. Lett. | pmid:21981393 |
Kao CL et al. | Stereochemical analysis of isopentenyl diphosphate isomerase type II from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. | 2005 | Org. Lett. | pmid:16321020 |
Scholte AA and Vederas JC | Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis. | 2006 | Org. Biomol. Chem. | pmid:16467948 |
Kumari U and Heese K | Cardiovascular dementia - a different perspective. | 2010 | Open Biochem J | pmid:20448820 |