MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhang J et al. | Expression, crystallization and preliminary crystallographic study of octaprenyl pyrophosphate synthase from Helicobacter pylori. | 2011 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:21301101 |
Hoshino T et al. | Crystallization and preliminary X-ray analysis of isopentenyl diphosphate isomerase from Methanocaldococcus jannaschii. | 2011 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:21206036 |
Byres E et al. | A preliminary crystallographic analysis of the putative mevalonate diphosphate decarboxylase from Trypanosoma brucei. | 2005 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:16511101 |
de Ruyck J et al. | Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals. | 2008 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:18391416 |
Björkelid C et al. | Structural and functional studies of mycobacterial IspD enzymes. | 2011 | Acta Crystallogr. D Biol. Crystallogr. | pmid:21543842 |
Ariyawutthiphan O et al. | Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. | 2012 | Acta Crystallogr. D Biol. Crystallogr. | pmid:23090405 |
Kamińska J et al. | Rsp5 ubiquitin ligase affects isoprenoid pathway and cell wall organization in S. cerevisiae. | 2005 | Acta Biochim. Pol. | pmid:15827618 |
Szkopińska A and Płochocka D | Farnesyl diphosphate synthase; regulation of product specificity. | 2005 | Acta Biochim. Pol. | pmid:15827605 |
Wanke M et al. | Isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate/2-C-methyl-D-erythritol 4-phosphate (DOXP/MEP) pathway. | 2001 | Acta Biochim. Pol. | pmid:11833775 |
Dellas N and Noel JP | Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. | 2010 | ACS Chem. Biol. | pmid:20392112 |