| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Na-Bangchang K et al. | Pharmacokinetics and pharmacodynamics of fosmidomycin monotherapy and combination therapy with clindamycin in the treatment of multidrug resistant falciparum malaria. | 2007 | Malar. J. | pmid:17531088 |
| Clizbe DB et al. | IDI2, a second isopentenyl diphosphate isomerase in mammals. | 2007 | J. Biol. Chem. | pmid:17202134 |
| Bulashevska S et al. | New insights into the genetic regulation of Plasmodium falciparum obtained by Bayesian modeling. | 2007 | Gene Regul Syst Bio | pmid:19936084 |
| Sgraja T et al. | Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. | 2007 | BMC Struct. Biol. | pmid:17397541 |
| Puan KJ et al. | Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. | 2007 | Int. Immunol. | pmid:17446209 |
| Henriksson LM et al. | Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. | 2007 | J. Biol. Chem. | pmid:17491006 |
| Rothman SC et al. | Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. | 2007 | Biochemistry | pmid:17428035 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Glickman JF and Schmid A | Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. | 2007 | Assay Drug Dev Technol | pmid:17477829 |
| Hebbeler AM et al. | Individual Vgamma2-Jgamma1.2+ T cells respond to both isopentenyl pyrophosphate and Daudi cell stimulation: generating tumor effectors with low molecular weight phosphoantigens. | 2007 | Cancer Immunol. Immunother. | pmid:17131122 |
| Scott KM et al. | The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. | 2006 | PLoS Biol. | pmid:17105352 |
| Kloer DP et al. | Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. | 2006 | Biochemistry | pmid:17176041 |
| Gibon Y et al. | Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. | 2006 | Genome Biol. | pmid:16916443 |
| Thulasiram HV and Poulter CD | Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. | 2006 | J. Am. Chem. Soc. | pmid:17147392 |
| Forster AC and Church GM | Towards synthesis of a minimal cell. | 2006 | Mol. Syst. Biol. | pmid:16924266 |
| Depasquale I and Wheatley DN | Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines. | 2006 | Cancer Cell Int. | pmid:16573823 |
| Chang TH et al. | Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination. | 2006 | J. Biol. Chem. | pmid:16554305 |
| Kharel Y et al. | Manipulation of prenyl chain length determination mechanism of cis-prenyltransferases. | 2006 | FEBS J. | pmid:16420487 |
| Goffinet M et al. | Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells. | 2006 | BMC Cancer | pmid:16539721 |
| Houde M et al. | Wheat EST resources for functional genomics of abiotic stress. | 2006 | BMC Genomics | pmid:16772040 |
| Chemler JA et al. | Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. | 2006 | Microb. Cell Fact. | pmid:16719921 |
| Kim SJ et al. | Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16532312 |
| Workalemahu G et al. | Expression of metalloproteinase-7 (matrilysin) in human blood and bronchoalveolar gamma/delta T-lymphocytes. Selective upregulation by the soluble non-peptidic mycobacterial phosphoantigen (isopentenyl pyrophosphate). | 2006 | J. Cell. Physiol. | pmid:16250011 |
| Zahiri HS et al. | Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. | 2006 | Metab. Eng. | pmid:16815062 |
| Caccamo N et al. | Sex-specific phenotypical and functional differences in peripheral human Vgamma9/Vdelta2 T cells. | 2006 | J. Leukoc. Biol. | pmid:16461739 |
| Scholte AA and Vederas JC | Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis. | 2006 | Org. Biomol. Chem. | pmid:16467948 |
| Fischbach MA and Walsh CT | Biochemistry. Directing biosynthesis. | 2006 | Science | pmid:17068249 |
| Theivagt AE et al. | Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity. | 2006 | Biochemistry | pmid:17128979 |
| Zahiri HS et al. | Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16896603 |
| Muñoz-Bertomeu J et al. | Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. | 2006 | Plant Physiol. | pmid:16980564 |
| Herzig C et al. | Bovine T cell receptor gamma variable and constant genes: combinatorial usage by circulating gammadelta T cells. | 2006 | Immunogenetics | pmid:16541255 |
| Cervantes-Cervantes M et al. | Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. | 2006 | Plant Physiol. | pmid:16581875 |
| Yoon SH et al. | Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. | 2006 | Biotechnol. Bioeng. | pmid:16547999 |
| Maurice T et al. | Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection. | 2006 | Pharmacol. Biochem. Behav. | pmid:16945406 |
| Grochowski LL et al. | Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. | 2006 | J. Bacteriol. | pmid:16621811 |
| Kavanagh KL et al. | The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. | 2006 | J. Biol. Chem. | pmid:16698791 |
| Hsiao YY et al. | Comparison of transcripts in Phalaenopsis bellina and Phalaenopsis equestris (Orchidaceae) flowers to deduce monoterpene biosynthesis pathway. | 2006 | BMC Plant Biol. | pmid:16836766 |
| Thompson K et al. | Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. | 2006 | Blood | pmid:16179378 |
| Vadali RV et al. | Enhanced lycopene productivity by manipulation of carbon flow to isopentenyl diphosphate in Escherichia coli. | 2005 Sep-Oct | Biotechnol. Prog. | pmid:16209562 |
| da Costa BM et al. | Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. | 2005 Jan-Feb | Biomacromolecules | pmid:15638531 |
| Re F et al. | Skewed representation of functionally distinct populations of Vgamma9Vdelta2 T lymphocytes in aging. | 2005 Jan-Feb | Exp. Gerontol. | pmid:15664733 |
| Ku B et al. | Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | 2005 | Appl. Environ. Microbiol. | pmid:16269684 |
| Park YC et al. | Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15459799 |
| Seker T et al. | Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15448940 |
| Chen AP et al. | Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. | 2005 | Biochem. J. | pmid:15447632 |
| Dudareva N et al. | The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15630092 |
| Conti L et al. | Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines. | 2005 | J. Immunol. | pmid:15611247 |
| Kao CL et al. | Stereochemical analysis of isopentenyl diphosphate isomerase type II from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. | 2005 | Org. Lett. | pmid:16321020 |