| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Withers ST et al. | Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. | 2007 | Appl. Environ. Microbiol. | pmid:17693564 |
| Bessoff K et al. | Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth. | 2013 | Antimicrob. Agents Chemother. | pmid:23380723 |
| Bowman JD et al. | Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. | 2014 | Antimicrob. Agents Chemother. | pmid:24247137 |
| Testa CA and Johnson LJ | A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. | 2012 | Antimicrob. Agents Chemother. | pmid:22777049 |
| Mönkkönen H et al. | Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth. | 2008 | Anticancer Drugs | pmid:18454049 |
| Zhao L et al. | Methylerythritol phosphate pathway of isoprenoid biosynthesis. | 2013 | Annu. Rev. Biochem. | pmid:23746261 |
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| Teufel R et al. | One-pot enzymatic synthesis of merochlorin A and B. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25115835 |
| Zhou C et al. | Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. | 2013 | Anal. Biochem. | pmid:23747531 |
| Nagel R et al. | Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. | 2012 | Anal. Biochem. | pmid:22266300 |
| Bruenger E and Rilling HC | Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. | 1988 | Anal. Biochem. | pmid:3189812 |
| Dozier JK and Distefano MD | An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. | 2012 | Anal. Biochem. | pmid:22085443 |
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| Tait RM | Development of a radiometric spot-wash assay for squalene synthase. | 1992 | Anal. Biochem. | pmid:1416027 |
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| Pires PW et al. | Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26453324 |
| Riedel DJ et al. | Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells. | 2009 | AIDS | pmid:19609200 |
| Boylston WH et al. | Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. | 2004 | Aging Cell | pmid:15379852 |
| Sahm H et al. | Biochemistry and physiology of hopanoids in bacteria. | 1993 | Adv. Microb. Physiol. | pmid:8310881 |
| Byres E et al. | A preliminary crystallographic analysis of the putative mevalonate diphosphate decarboxylase from Trypanosoma brucei. | 2005 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:16511101 |