Fujikura K et al. |
Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26. |
2000 |
J. Biochem. |
pmid:11098133
|
Kawasaki T et al. |
Interconversion of the product specificity of type I eubacterial farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase through one amino acid substitution. |
2003 |
J. Biochem. |
pmid:12761202
|
Fujisaki S et al. |
Biosynthesis of isoprenoids in intact cells of Escherichia coli. |
1986 |
J. Biochem. |
pmid:3519600
|
Fujisaki S et al. |
Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis. |
1986 |
J. Biochem. |
pmid:3519603
|
Koyama T et al. |
Isoprenoid enzyme systems of silkworm. II. Formation of the juvenile hormone skeletons by farnesyl pyrophosphate synthetase II. |
1985 |
J. Biochem. |
pmid:4066650
|
Koyama T et al. |
Two forms of farnesyl pyrophosphate synthetase from hog liver. |
1977 |
J. Biochem. |
pmid:599144
|
Fujisaki S et al. |
Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. |
2005 |
J. Biochem. |
pmid:15809342
|
Takahashi I and Ogura K |
Farnesyl pyrophosphate synthetase from Bacillus subtilis. |
1981 |
J. Biochem. |
pmid:6792191
|
Nakanishi S et al. |
Preparation of 14C-labeled and unlabeled sterol intermediates from yeast using metabolic inhibitors. |
1984 |
J. Biochem. |
pmid:6397465
|
Sagami H and Ogura K |
Geranylgeranyl pyrophosphate synthetase lacking geranyl-transferring activity from Micrococcus luteus. |
1981 |
J. Biochem. |
pmid:7275954
|
Sagami H and Ogura K |
Multiple forms of isopentenyl pyrophosphate isomerase of avian liver. |
1983 |
J. Biochem. |
pmid:6643431
|
Ohnuma S et al. |
Effects of random mutagenesis in a putative substrate-binding domain of geranylgeranyl diphosphate synthase upon intermediate formation and substrate specificity. |
1997 |
J. Biochem. |
pmid:9163520
|
Sutherlin A et al. |
Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis. |
2002 |
J. Bacteriol. |
pmid:12107122
|
Kuzuyama T et al. |
Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis. |
2000 |
J. Bacteriol. |
pmid:10648511
|
Hahn FM et al. |
1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. |
2001 |
J. Bacteriol. |
pmid:11114895
|
Nakatani H et al. |
Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae. |
2012 |
J. Bacteriol. |
pmid:22505674
|
Takagi M et al. |
A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190. |
2000 |
J. Bacteriol. |
pmid:10894721
|
Wilding EI et al. |
Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci. |
2000 |
J. Bacteriol. |
pmid:10894743
|
Fujisaki S et al. |
Isolation and characterization of an Escherichia coli mutant having temperature-sensitive farnesyl diphosphate synthase. |
1989 |
J. Bacteriol. |
pmid:2676985
|
Balibar CJ et al. |
The mevalonate pathway of Staphylococcus aureus. |
2009 |
J. Bacteriol. |
pmid:19028897
|
Altincicek B et al. |
GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. |
2001 |
J. Bacteriol. |
pmid:11274098
|
Grochowski LL et al. |
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. |
2006 |
J. Bacteriol. |
pmid:16621811
|
Ershov YV et al. |
Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. |
2002 |
J. Bacteriol. |
pmid:12193620
|
Inoue A et al. |
Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli. |
2008 |
J. Bacteriol. |
pmid:18708495
|
Cunningham FX et al. |
Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. |
2000 |
J. Bacteriol. |
pmid:11004185
|
Hedl M et al. |
Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis. |
2002 |
J. Bacteriol. |
pmid:11914342
|
Poliquin K et al. |
Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. |
2004 |
J. Bacteriol. |
pmid:15231801
|
Morikawa S et al. |
Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins. |
2005 |
J. Atheroscler. Thromb. |
pmid:16020911
|
Terano T et al. |
Geranylgeranylpyrophosphate plays a key role for the G1 to S transition in vascular smooth muscle cells. |
1998 |
J. Atheroscler. Thromb. |
pmid:10077451
|
Zenitani S et al. |
Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. |
2003 |
J. Antibiot. |
pmid:14513904
|
Kawasaki T et al. |
A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. |
2003 |
J. Antibiot. |
pmid:14763562
|
Rekittke I et al. |
Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. |
2008 |
J. Am. Chem. Soc. |
pmid:19035630
|
Wouters J et al. |
A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase. |
2005 |
J. Am. Chem. Soc. |
pmid:15643873
|
Wu Z et al. |
Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate. |
2005 |
J. Am. Chem. Soc. |
pmid:16332094
|
Heaps NA and Poulter CD |
Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism. |
2011 |
J. Am. Chem. Soc. |
pmid:22047048
|
Chen AP et al. |
Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase. |
2002 |
J. Am. Chem. Soc. |
pmid:12487597
|
Thulasiram HV and Poulter CD |
Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. |
2006 |
J. Am. Chem. Soc. |
pmid:17147392
|
Thibodeaux CJ et al. |
Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. |
2010 |
J. Am. Chem. Soc. |
pmid:20593767
|
Kakinuma K et al. |
New approach to multiply deuterated isoprenoids using triply engineered Escherichia coli and its potential as a tool for mechanistic enzymology. |
2001 |
J. Am. Chem. Soc. |
pmid:11456682
|
Jonnalagadda V et al. |
Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. |
2012 |
J. Am. Chem. Soc. |
pmid:22471428
|
Kondo M et al. |
Expansion of human peripheral blood γδ T cells using zoledronate. |
2011 |
J Vis Exp |
pmid:21931292
|
Pan J et al. |
ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer. |
2011 |
J Transl Med |
pmid:22152132
|
Rogers TL and Holen I |
Tumour macrophages as potential targets of bisphosphonates. |
2011 |
J Transl Med |
pmid:22005011
|
French CE |
Synthetic biology and biomass conversion: a match made in heaven? |
2009 |
J R Soc Interface |
pmid:19454530
|
Gresh N et al. |
Analysis of the interactions taking place in the recognition site of a bimetallic Mg(II)-Zn(II) enzyme, isopentenyl diphosphate isomerase. a parallel quantum-chemical and polarizable molecular mechanics study. |
2010 |
J Phys Chem B |
pmid:20329783
|
Hussain MS et al. |
Current approaches toward production of secondary plant metabolites. |
2012 |
J Pharm Bioallied Sci |
pmid:22368394
|
Brannian J et al. |
Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study. |
2009 |
J Ovarian Res |
pmid:19650929
|
Bock O et al. |
Common musculoskeletal adverse effects of oral treatment with once weekly alendronate and risedronate in patients with osteoporosis and ways for their prevention. |
2007 Apr-Jun |
J Musculoskelet Neuronal Interact |
pmid:17627083
|
de Souza W and Rodrigues JC |
Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. |
2009 |
Interdiscip Perspect Infect Dis |
pmid:19680554
|
Zhang J et al. |
Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases. |
2012 |
Int. J. Biochem. Cell Biol. |
pmid:22982238
|
Puan KJ et al. |
Preferential recognition of a microbial metabolite by human Vgamma2Vdelta2 T cells. |
2007 |
Int. Immunol. |
pmid:17446209
|
Chang CW et al. |
Identification and categorization of liver toxicity markers induced by a related pair of drugs. |
2011 |
Int J Mol Sci |
pmid:21845099
|
Song AA et al. |
Functional expression of an orchid fragrance gene in Lactococcus lactis. |
2012 |
Int J Mol Sci |
pmid:22408409
|
Iriti M and Faoro F |
Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. |
2009 |
Int J Mol Sci |
pmid:20111684
|
Li X et al. |
Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus. |
2009 |
Int J Microbiol |
pmid:20016671
|
Diaz ME et al. |
Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. |
2012 |
Insect Biochem. Mol. Biol. |
pmid:22782071
|
Kinjoh T et al. |
Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata. |
2007 |
Insect Biochem. Mol. Biol. |
pmid:17628279
|
Sicard H and Fournie JJ |
Metabolic routes as targets for immunological discrimination of host and parasite. |
2000 |
Infect. Immun. |
pmid:10899832
|
Xia M et al. |
A Subset of Protective γ9δ2 T Cells Is Activated by Novel Mycobacterial Glycolipid Components. |
2016 |
Infect. Immun. |
pmid:27297390
|
Srivastava A et al. |
Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target. |
2008 |
Infect Disord Drug Targets |
pmid:18473904
|
Gogoi D and Chiplunkar SV |
Targeting gamma delta T cells for cancer immunotherapy: bench to bedside. |
2013 |
Indian J. Med. Res. |
pmid:24434328
|
Srivastava NK and Srivastava AK |
Influence of Some Heavy Metals on Growth, Alkaloid Content and Composition in Catharanthus roseus L. |
2010 |
Indian J Pharm Sci |
pmid:21969751
|
Martini F et al. |
gammadelta T-cell anergy in human immunodeficiency virus-infected persons with opportunistic infections and recovery after highly active antiretroviral therapy. |
2000 |
Immunology |
pmid:10929075
|
Kunzmann V et al. |
Polyinosinic-polycytidylic acid-mediated stimulation of human gammadelta T cells via CD11c dendritic cell-derived type I interferons. |
2004 |
Immunology |
pmid:15196204
|
Li H and David Pauza C |
Interplay of T-cell receptor and interleukin-2 signalling in Vγ2Vδ2 T-cell cytotoxicity. |
2011 |
Immunology |
pmid:20738419
|
Campos Alberto EJ et al. |
Differential effects of tumour necrosis factor-alpha and interleukin-12 on isopentenyl pyrophosphate-stimulated interferon-gamma production by cord blood Vgamma9 T cells. |
2009 |
Immunology |
pmid:19019091
|
Cairo C et al. |
The Vgamma2/Vdelta2 T-cell repertoire in Macaca fascicularis: functional responses to phosphoantigen stimulation by the Vgamma2/Jgamma1.2 subset. |
2005 |
Immunology |
pmid:15885125
|
Evans PS et al. |
In vitro stimulation with a non-peptidic alkylphosphate expands cells expressing Vgamma2-Jgamma1.2/Vdelta2 T-cell receptors. |
2001 |
Immunology |
pmid:11576216
|
Herzig C et al. |
Bovine T cell receptor gamma variable and constant genes: combinatorial usage by circulating gammadelta T cells. |
2006 |
Immunogenetics |
pmid:16541255
|
Amslinger S et al. |
Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. |
2007 |
Immunobiology |
pmid:17270709
|
Omoigui S |
The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. |
2007 |
Immun Ageing |
pmid:17374166
|
Derhovanessian E et al. |
Immunity, ageing and cancer. |
2008 |
Immun Ageing |
pmid:18816370
|
Sireci G et al. |
Patterns of phosphoantigen stimulation of human Vgamma9/Vdelta2 T cell clones include Th0 cytokines. |
1997 |
Hum. Immunol. |
pmid:9475336
|
Klein O and Porra RJ |
The participation of the Shemin and C5 pathways in 5-aminolaevulinate and chlorophyll formation in higher plants and facultative photosynthetic bacteria. |
1982 |
Hoppe-Seyler's Z. Physiol. Chem. |
pmid:7106702
|
Smit A and Mushegian A |
Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway. |
2000 |
Genome Res. |
pmid:11042147
|
Gibon Y et al. |
Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. |
2006 |
Genome Biol. |
pmid:16916443
|
Hackl H et al. |
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. |
2005 |
Genome Biol. |
pmid:16420668
|
Huang J and Gogarten JP |
Did an ancient chlamydial endosymbiosis facilitate the establishment of primary plastids? |
2007 |
Genome Biol. |
pmid:17547748
|
Glazko GV and Mushegian AR |
Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns. |
2004 |
Genome Biol. |
pmid:15128446
|
Sharman A |
The many uses of a genome sequence. |
2001 |
Genome Biol. |
pmid:11423005
|
Kastenmüller G et al. |
Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes. |
2009 |
Genome Biol. |
pmid:19284550
|
Wille A et al. |
Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana. |
2004 |
Genome Biol. |
pmid:15535868
|
Whitaker JW et al. |
The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. |
2009 |
Genome Biol. |
pmid:19368726
|
Desmond E and Gribaldo S |
Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature. |
2009 |
Genome Biol Evol |
pmid:20333205
|
Bulashevska S et al. |
New insights into the genetic regulation of Plasmodium falciparum obtained by Bayesian modeling. |
2007 |
Gene Regul Syst Bio |
pmid:19936084
|
Hümbelin M et al. |
Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens. |
2002 |
Gene |
pmid:12384294
|
Sawai S and Saito K |
Triterpenoid biosynthesis and engineering in plants. |
2011 |
Front Plant Sci |
pmid:22639586
|
Wurtzel ET et al. |
Maize provitamin a carotenoids, current resources, and future metabolic engineering challenges. |
2012 |
Front Plant Sci |
pmid:22645578
|
Lamsen EN and Atsumi S |
Recent progress in synthetic biology for microbial production of C3-C10 alcohols. |
2012 |
Front Microbiol |
pmid:22701113
|
Grolle S et al. |
Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. |
2000 |
FEMS Microbiol. Lett. |
pmid:11004410
|
Horbach S et al. |
Isoprenoid biosynthesis in bacteria: two different pathways? |
1993 |
FEMS Microbiol. Lett. |
pmid:8405922
|
Disch A and Rohmer M |
On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. |
1998 |
FEMS Microbiol. Lett. |
pmid:9835029
|
Jomaa H et al. |
Vgamma9/Vdelta2 T cell activation induced by bacterial low molecular mass compounds depends on the 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid biosynthesis. |
1999 |
FEMS Immunol. Med. Microbiol. |
pmid:10497868
|
Tritsch D et al. |
Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures. |
2010 |
FEBS Lett. |
pmid:19903472
|
Ohnuma S et al. |
Kinetic studies on the prenyl chain elongation by undecaprenyl diphosphate synthase with artificial substrate homologues. |
1989 |
FEBS Lett. |
pmid:2509247
|
Lichtenthaler HK et al. |
Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. |
1997 |
FEBS Lett. |
pmid:9009212
|
Schwender J et al. |
Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. |
1997 |
FEBS Lett. |
pmid:9305746
|
Contin A et al. |
The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture. |
1998 |
FEBS Lett. |
pmid:9742965
|
RodrÃguez-Concepción M et al. |
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. |
2000 |
FEBS Lett. |
pmid:10818234
|
Miller B et al. |
Functional involvement of a deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. |
2000 |
FEBS Lett. |
pmid:11007968
|