MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Koyama T et al. | Isoprenoid enzyme systems of silkworm. I. Partial purification of isopentenyl pyrophosphate isomerase, farnesyl pyrophosphate synthetase, and geranylgeranyl pyrophosphate synthetase. | 1985 | J. Biochem. | pmid:4066649 |
Koyama T et al. | Isoprenoid enzyme systems of silkworm. II. Formation of the juvenile hormone skeletons by farnesyl pyrophosphate synthetase II. | 1985 | J. Biochem. | pmid:4066650 |
Popják G and Hadley C | Inhibition of liver prenyltransferase by citronellyl and geranyl phosphonate and phosphonylphosphate. | 1985 | J. Lipid Res. | pmid:4067435 |
Skilleter DN and Kekwick RG | The enzymes forming isopentenyl pyrophosphate from 5-phosphomevalonate (mevalonate 5-phosphate) in the latex of Hevea brasiliensis. | 1971 | Biochem. J. | pmid:4333851 |
Momose K and Rudney H | 3-Polyprenyl-4-hydroxybenzoate synthesis in the inner membrane of mitochondria from p-hydroxybenzoate and isopentenylpyrophosphate. A demonstration of isoprenoid synthesis in rat liver mitochondria. | 1972 | J. Biol. Chem. | pmid:4338233 |
Thomas G and Threlfall DR | Polyprenyl pyrophosphate-p-hydroxybenzoate polyprenyltransferase activity in mitochondria of broad-bean seeds and yeast. | 1973 | Biochem. J. | pmid:4356126 |
Koyama T et al. | Studies on isopentenyl pyrophosphate isomerase with artificial substrates. | 1973 | J. Biol. Chem. | pmid:4356618 |
Jedlicki E et al. | Stereospecificity of isopentenylpyrophosphate isomerase and prenyl transferase from pinus and citrus. | 1972 | Arch. Biochem. Biophys. | pmid:4635785 |
Milborrow BV | Stereochemical aspects of the formation of double bonds in abscisic acid. | 1972 | Biochem. J. | pmid:4643698 |
Banthorpe DV and Le Patourel GN | The biosynthesis of (+)- -pinene in Pinus species. | 1972 | Biochem. J. | pmid:4656792 |