| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
Cross Reference
Introduction
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Isopentenyl pyrophosphate?
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Isopentenyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Isopentenyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Isopentenyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Isopentenyl pyrophosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Boëdec A et al. | Synthesis and biological activity of phosphonate analogues and geometric isomers of the highly potent phosphoantigen (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate. | 2008 | J. Med. Chem. | pmid:18303828 |
| Lee M et al. | Biosynthesis of isoprenoids: crystal structure of the [4Fe-4S] cluster protein IspG. | 2010 | J. Mol. Biol. | pmid:20932974 |
| Span I et al. | Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. | 2012 | J. Mol. Biol. | pmid:22137895 |
| Wang W et al. | The structural basis of chain length control in Rv1086. | 2008 | J. Mol. Biol. | pmid:18597781 |
| Byres E et al. | Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity. | 2007 | J. Mol. Biol. | pmid:17583736 |
| Itoh D et al. | Nonequivalent labeling of the phytyl side chain of chlorophyll a in callus of the hornwort Anthoceros punctatus. | 2000 | J. Nat. Prod. | pmid:10978203 |
| Crick DC et al. | Characterization and localization of a long-chain isoprenyltransferase activity in porcine brain: proposed role in the biosynthesis of dolichyl phosphate. | 1991 | J. Neurochem. | pmid:1895109 |
| Holte D et al. | An approach to mimicking the sesquiterpene cyclase phase by nickel-promoted diene/alkyne cooligomerization. | 2012 | J. Org. Chem. | pmid:22229741 |
| Amslinger S et al. | Biosynthesis of terpenes. Preparation of (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate, an intermediate of the deoxyxylulose phosphate pathway. | 2002 | J. Org. Chem. | pmid:12076162 |
| Heaps NA and Poulter CD | Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase. | 2011 | J. Org. Chem. | pmid:21344952 |
| Phan RM and Poulter CD | Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. | 2001 | J. Org. Chem. | pmid:11578224 |
| Krasutsky SG et al. | Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. | 2014 | J. Org. Chem. | pmid:25184438 |
| Dolzhenko Y et al. | UV-B modulates the interplay between terpenoids and flavonoids in peppermint (Mentha x piperita L.). | 2010 | J. Photochem. Photobiol. B, Biol. | pmid:20627615 |
| Thabet I et al. | The subcellular localization of periwinkle farnesyl diphosphate synthase provides insight into the role of peroxisome in isoprenoid biosynthesis. | 2011 | J. Plant Physiol. | pmid:21872968 |
| Wang Y et al. | The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. | 2008 | J. Proteome Res. | pmid:18303831 |
| Berkun Y et al. | GammadeltaT cells in juvenile idiopathic arthritis: higher percentages of synovial Vdelta1+ and Vgamma9+ T cell subsets are associated with milder disease. | 2011 | J. Rheumatol. | pmid:21406498 |
| Begley DW et al. | Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. | 2011 | J. Struct. Funct. Genomics | pmid:21359640 |
| Qin G et al. | Type 1 responses of human Vγ9Vδ2 T cells to influenza A viruses. | 2011 | J. Virol. | pmid:21752902 |
| Modi ND and Lentzsch S | Bisphosphonates as antimyeloma drugs. | 2012 | Leukemia | pmid:22005788 |
| Mönkkönen H et al. | Zoledronic acid-induced IPP/ApppI production in vivo. | 2007 | Life Sci. | pmid:17850825 |