MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hunter WN | Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. | 2011 | Curr Top Med Chem | pmid:21619509 |
Rogers TL and Holen I | Tumour macrophages as potential targets of bisphosphonates. | 2011 | J Transl Med | pmid:22005011 |
Luo H et al. | Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. | 2011 | BMC Genomics | pmid:22369100 |
Silverman SL et al. | Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid. | 2011 | Osteoporos Int | pmid:21116816 |
Ohno K et al. | Computational insights into binding of bisphosphates to farnesyl pyrophosphate synthase. | 2011 | Curr. Med. Chem. | pmid:21110804 |
Bang S et al. | Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels. | 2011 | Pain | pmid:21353389 |
Davey MS et al. | Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. | 2011 | PLoS Pathog. | pmid:21589907 |
Baumeister S et al. | Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. | 2011 | PLoS ONE | pmid:21573242 |
Schmidt A et al. | Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). | 2011 | Plant Mol. Biol. | pmid:22002747 |
Meier S et al. | A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. | 2011 | BMC Syst Biol | pmid:21595952 |