MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
---|---|---|
Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zhou C et al. | Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. | 2013 | Anal. Biochem. | pmid:23747531 |
Nagel R et al. | Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. | 2012 | Anal. Biochem. | pmid:22266300 |
Bruenger E and Rilling HC | Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis. | 1988 | Anal. Biochem. | pmid:3189812 |
Dozier JK and Distefano MD | An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. | 2012 | Anal. Biochem. | pmid:22085443 |
Tait RM | Development of a radiometric spot-wash assay for squalene synthase. | 1992 | Anal. Biochem. | pmid:1416027 |
Tong H et al. | Quantitative determination of isopentenyl diphosphate in cultured mammalian cells. | 2013 | Anal. Biochem. | pmid:23000003 |
Gräwert T et al. | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19569147 |
Teufel R et al. | One-pot enzymatic synthesis of merochlorin A and B. | 2014 | Angew. Chem. Int. Ed. Engl. | pmid:25115835 |
Zhao L et al. | Methylerythritol phosphate pathway of isoprenoid biosynthesis. | 2013 | Annu. Rev. Biochem. | pmid:23746261 |
Mönkkönen H et al. | Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth. | 2008 | Anticancer Drugs | pmid:18454049 |