MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
MeSH term | MeSH ID | Detail |
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Melanoma | D008545 | 69 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bessoff K et al. | Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth. | 2013 | Antimicrob. Agents Chemother. | pmid:23380723 |
Bowman JD et al. | Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. | 2014 | Antimicrob. Agents Chemother. | pmid:24247137 |
Testa CA and Johnson LJ | A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. | 2012 | Antimicrob. Agents Chemother. | pmid:22777049 |
Ku B et al. | Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | 2005 | Appl. Environ. Microbiol. | pmid:16269684 |
Withers ST et al. | Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. | 2007 | Appl. Environ. Microbiol. | pmid:17693564 |
Chou HH and Keasling JD | Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. | 2012 | Appl. Environ. Microbiol. | pmid:22941086 |
Singkaravanit S et al. | Geranylgeranyl diphosphate synthase genes in entomopathogenic fungi. | 2010 | Appl. Microbiol. Biotechnol. | pmid:19690851 |
Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
Kim SJ et al. | Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16532312 |
Zahiri HS et al. | Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16896603 |